Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     390
XP_006716142                                                           20     390
XP_005250088                                                           20     390
XP_006716141                                                           20     390
XP_005250085                                                           20     390
XP_006716140                                                           20     390
XP_005250084                                                           20     390
XP_005250083                                                           20     390
XP_005250082                                                           20     390
NP_689777                                                              16    5631
NP_060360                                                              16    5631
NP_116753                                                              16    5631
NP_116754                                                              16    5631
NP_056058                                                              16    5631
NP_001265548                                                           16    5631
NP_116755                                                              16    5631
NP_116749                                                              16    5631
NP_001161834                                                           16    5631
NP_001161832                                                           16    5631
NP_116750                                                              16    5631
NP_001161833                                                           16    5631
NP_116751                                                              16    5631
NP_001161835                                                           16    5631
NP_055337                                                              16    5631
XP_006716574                                                           16    5631
XP_006716573                                                           16    5631
XP_005250858                                                           16    5631
XP_005250857                                                           16    5631
NP_001177203                                                           16    7355
NP_079409                                                              16    7355
XP_005264631                                                           16    7355
XP_005264630                                                           16    7355
XP_005264629                                                           16    7355
NP_001188413                                                           15    9605
NP_116023                                                              15    9605
NP_690577                                                              15    9605
NP_001186189                                                           15    9605
NP_659471                                                              15    9605
NP_689500                                                              15    9605
NP_001106997                                                           15    9605
NP_001026873                                                           15    9605
NP_068834                                                              15    9605
NP_066278                                                              15    9605
NP_001258662                                                           15    9605
XP_005256385                                                           15    9605
XP_006721400                                                           15    9605
XP_005256381                                                           15    9605
XP_005251676                                                           15    9605
XP_005250186                                                           15    9605
XP_006715638                                                           15    9605
XP_005267216                                                           15    9605
XP_006713274                                                           15    9605
XP_005265300                                                           15    9605
XP_005265299                                                           15    9605
XP_005265298                                                           15    9605
XP_006713273                                                           15    9605
XP_005265297                                                           15    9605
XP_006713231                                                           15    9605
XP_006713229                                                           15    9605
XP_005244996                                                           15    9605
NP_115521                                                              15    9605
>NP_733751
          Length = 4911

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1625 ENDTMSNAQ 1633
>XP_006716142
          Length = 4927

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_005250088
          Length = 4928

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_006716141
          Length = 4959

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_005250085
          Length = 4979

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_006716140
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_005250084
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>XP_005250083
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1641 ENDTMSNAQ 1649
>XP_005250082
          Length = 4983

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDTMLNAQ 9
            ENDTM NAQ
Sbjct: 1642 ENDTMSNAQ 1650
>NP_689777
          Length = 3997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>NP_060360
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>NP_116753
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 723 DNDTGMNAE 731
>NP_116754
          Length = 1048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 734 DNDTGMNAE 742
>NP_056058
          Length = 863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>NP_001265548
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 723 DNDTGMNAE 731
>NP_116755
          Length = 1340

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 734 DNDTGMNAE 742
>NP_116749
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_001161834
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_001161832
          Length = 1339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_116750
          Length = 1347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_001161833
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_116751
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_001161835
          Length = 1329

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>NP_055337
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           +NDT +NA+
Sbjct: 702 DNDTGMNAE 710
>XP_006716574
          Length = 968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>XP_006716573
          Length = 1776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>XP_005250858
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>XP_005250857
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENDTMLNAQ 9
           EN+T+LN +
Sbjct: 619 ENETILNPE 627
>NP_001177203
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 747 ENDIFRNAQ 755
>NP_079409
          Length = 843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 663 ENDIFRNAQ 671
>XP_005264631
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 746 ENDIFRNAQ 754
>XP_005264630
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 746 ENDIFRNAQ 754
>XP_005264629
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 747 ENDIFRNAQ 755
>NP_001188413
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 267 ENDTLL 272
>NP_116023
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 267 ENDTLL 272
>NP_690577
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 267 ENDTLL 272
>NP_001186189
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ENDTMLNAQ 9
          END  +N+Q
Sbjct: 18 ENDPSVNSQ 26
>NP_659471
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ENDTMLNAQ 9
          END  +N+Q
Sbjct: 18 ENDPSVNSQ 26
>NP_689500
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 294 ENDKKQNAQ 302
>NP_001106997
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 369 ENDKKQNAQ 377
>NP_001026873
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 192 ENDILLN 198
>NP_068834
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 402 ENDTLL 407
>NP_066278
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NDTMLN 7
           NDT+LN
Sbjct: 629 NDTVLN 634
>NP_001258662
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NDTMLN 7
           NDT+LN
Sbjct: 593 NDTVLN 598
>XP_005256385
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 155 ENDKKQNAQ 163
>XP_006721400
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 294 ENDKKQNAQ 302
>XP_005256381
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ENDTMLNAQ 9
           END   NAQ
Sbjct: 352 ENDKKQNAQ 360
>XP_005251676
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 267 ENDTLL 272
>XP_005250186
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ENDTML 6
           ENDT+L
Sbjct: 284 ENDTLL 289
>XP_006715638
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NDTMLNAQ 9
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260
>XP_005267216
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NDTMLNAQ 9
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260
>XP_006713274
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 119 ENDILLN 125
>XP_005265300
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 143 ENDILLN 149
>XP_005265299
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 143 ENDILLN 149
>XP_005265298
          Length = 217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 143 ENDILLN 149
>XP_006713273
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 175 ENDILLN 181
>XP_005265297
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ENDTMLN 7
           END +LN
Sbjct: 189 ENDILLN 195
>XP_006713231
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NDTMLN 7
           NDT+LN
Sbjct: 529 NDTVLN 534
>XP_006713229
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NDTMLN 7
           NDT+LN
Sbjct: 584 NDTVLN 589
>XP_005244996
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ENDTMLNAQ 9
          END  +N+Q
Sbjct: 18 ENDPSVNSQ 26
>NP_115521
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NDTMLNAQ 9
           NDT  NAQ
Sbjct: 253 NDTNQNAQ 260
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.112    0.281 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,973
Number of extensions: 1035
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package