Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     665
NP_005913                                                              19     665
XP_005267046                                                           19     665
XP_005267045                                                           19     665
NP_056065                                                              17    2528
NP_001003800                                                           17    2528
NP_003322                                                              17    4312
NP_002635                                                              16    5631
XP_005273220                                                           16    5631
NP_001243143                                                           16    7355
NP_689509                                                              16    7355
NP_001243142                                                           16    7355
NP_000693                                                              16    7355
NP_001153705                                                           16    7355
NP_000692                                                              16    7355
NP_001153706                                                           16    7355
NP_056366                                                              16    7355
XP_005259010                                                           16    7355
XP_005265092                                                           16    7355
XP_005265091                                                           16    7355
XP_006710718                                                           16    7355
NP_001005283                                                           15    9605
NP_005087                                                              15    9605
NP_008877                                                              15    9605
NP_998821                                                              15    9605
NP_001164633                                                           15    9605
NP_066022                                                              15    9605
NP_963893                                                              15    9605
NP_003119                                                              15    9605
XP_005262367                                                           15    9605
XP_006724778                                                           15    9605
XP_005262366                                                           15    9605
XP_006723369                                                           15    9605
XP_005274250                                                           15    9605
XP_006718734                                                           15    9605
XP_006718733                                                           15    9605
XP_005274249                                                           15    9605
XP_006718732                                                           15    9605
XP_005264575                                                           15    9605
XP_006712150                                                           15    9605
XP_005264574                                                           15    9605
NP_842565                                                              15    9605
>NP_006715
          Length = 1558

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDRLVSIA 9
            ENDRL SIA
Sbjct: 1181 ENDRLASIA 1189
>NP_005913
          Length = 1608

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDRLVSIA 9
            ENDRL SIA
Sbjct: 1231 ENDRLASIA 1239
>XP_005267046
          Length = 1554

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDRLVSIA 9
            ENDRL SIA
Sbjct: 1177 ENDRLASIA 1185
>XP_005267045
          Length = 1604

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ENDRLVSIA 9
            ENDRL SIA
Sbjct: 1227 ENDRLASIA 1235
>NP_056065
          Length = 824

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENDRLVSIA 9
           EN+RL S+A
Sbjct: 138 ENERLASVA 146
>NP_001003800
          Length = 855

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENDRLVSIA 9
           EN+RL S+A
Sbjct: 138 ENERLASVA 146
>NP_003322
          Length = 1187

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ENDRLVSI 8
            +NDRLV I
Sbjct: 1032 DNDRLVKI 1039
>NP_002635
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENDRLVSI 8
           EN RLVS+
Sbjct: 522 ENSRLVSL 529
>XP_005273220
          Length = 773

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENDRLVSI 8
           EN RLVS+
Sbjct: 522 ENSRLVSL 529
>NP_001243143
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 849 NERLISMA 856
>NP_689509
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 836 NERLISMA 843
>NP_001243142
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 847 NERLISMA 854
>NP_000693
          Length = 1020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 843 NERLISMA 850
>NP_001153705
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 846 NERLISMA 853
>NP_000692
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 846 NERLISMA 853
>NP_001153706
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 815 NERLISMA 822
>NP_056366
          Length = 629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENDRLVSIA 9
           + DRLVSI+
Sbjct: 246 KQDRLVSIS 254
>XP_005259010
          Length = 1261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 836 NERLISMA 843
>XP_005265092
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ENDRLVSIA 9
          + DRLVSI+
Sbjct: 68 KQDRLVSIS 76
>XP_005265091
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ENDRLVSIA 9
           + DRLVSI+
Sbjct: 183 KQDRLVSIS 191
>XP_006710718
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   NDRLVSIA 9
           N+RL+S+A
Sbjct: 815 NERLISMA 822
>NP_001005283
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ENDRLVSI 8
           E DR+VS+
Sbjct: 269 EGDRVVSV 276
>NP_005087
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1148 ENNRMVNI 1155
>NP_008877
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 443 ENQRLVS 449
>NP_998821
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 163 ENSRLVS 169
>NP_001164633
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1136 ENNRMVNI 1143
>NP_066022
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 447 ENQRLVS 453
>NP_963893
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1148 ENNRMVNI 1155
>NP_003119
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 440 ENQRLVS 446
>XP_005262367
          Length = 1358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1136 ENNRMVNI 1143
>XP_006724778
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1148 ENNRMVNI 1155
>XP_005262366
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ENDRLVSI 8
            EN+R+V+I
Sbjct: 1148 ENNRMVNI 1155
>XP_006723369
          Length = 2394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 447 ENQRLVS 453
>XP_005274250
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 443 ENQRLVS 449
>XP_006718734
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 443 ENQRLVS 449
>XP_006718733
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 443 ENQRLVS 449
>XP_005274249
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 443 ENQRLVS 449
>XP_006718732
          Length = 2397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 450 ENQRLVS 456
>XP_005264575
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 427 ENQRLVS 433
>XP_006712150
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 440 ENQRLVS 446
>XP_005264574
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 440 ENQRLVS 446
>NP_842565
          Length = 2155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ENDRLVS 7
           EN RLVS
Sbjct: 427 ENQRLVS 433
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.130    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 479,043
Number of extensions: 798
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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