Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
XP_005266703                                                           19     665
NP_998763                                                              17    3301
NP_001138501                                                           17    3301
XP_006722388                                                           17    3301
NP_937762                                                              16    5631
NP_001121189                                                           16    5631
NP_008877                                                              16    5631
NP_689691                                                              16    5631
NP_001001668                                                           16    5631
XP_005258968                                                           16    5631
XP_005258967                                                           16    5631
XP_006723273                                                           16    5631
XP_005258616                                                           16    5631
XP_005258615                                                           16    5631
XP_005274250                                                           16    5631
XP_006718734                                                           16    5631
XP_006718733                                                           16    5631
XP_005274249                                                           16    5631
XP_006718732                                                           16    5631
NP_001153332                                                           16    5631
NP_001153333                                                           16    5631
NP_001269973                                                           16    7355
NP_003156                                                              16    7355
NP_653267                                                              16    7355
NP_055805                                                              16    7355
NP_001269972                                                           16    7355
NP_919277                                                              16    7355
XP_005267555                                                           16    7355
XP_006720166                                                           16    7355
XP_005267550                                                           16    7355
XP_005267549                                                           16    7355
XP_005267548                                                           16    7355
XP_006720165                                                           16    7355
XP_006720164                                                           16    7355
XP_006720163                                                           16    7355
XP_006720162                                                           16    7355
XP_006720161                                                           16    7355
NP_001027392                                                           16    7355
NP_001258625                                                           15    9605
NP_001258627                                                           15    9605
NP_004290                                                              15    9605
NP_001258628                                                           15    9605
NP_443723                                                              15    9605
NP_001258626                                                           15    9605
NP_004201                                                              15    9605
NP_055836                                                              15    9605
NP_006626                                                              15    9605
XP_005258479                                                           15    9605
XP_006723039                                                           15    9605
XP_005270327                                                           15    9605
XP_005270326                                                           15    9605
XP_006717590                                                           15    9605
XP_005248755                                                           15    9605
XP_005248754                                                           15    9605
NP_005459                                                              15    9605
>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ENALLAQHS 9
           ENA LAQHS
Sbjct: 700 ENASLAQHS 708
>XP_005266703
          Length = 1501

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ENALLAQHS 9
          ENA LAQHS
Sbjct: 31 ENASLAQHS 39
>NP_998763
          Length = 600

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NALL QH
Sbjct: 210 KNALLVQH 217
>NP_001138501
          Length = 1392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    ENALLAQHS 9
            ENAL+++H+
Sbjct: 1256 ENALVSEHA 1264
>XP_006722388
          Length = 1511

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    ENALLAQHS 9
            ENAL+++H+
Sbjct: 1375 ENALVSEHA 1383
>NP_937762
          Length = 3333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ENALLAQH 8
           EN LL QH
Sbjct: 889 ENCLLYQH 896
>NP_001121189
          Length = 3277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ENALLAQH 8
           EN LL QH
Sbjct: 889 ENCLLYQH 896
>NP_008877
          Length = 2390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1102 ALLAQHA 1108
>NP_689691
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 279 QNAHLAQH 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 475 QNAGLAQH 482
>NP_001001668
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 520 QNAHLAQH 527
>XP_005258968
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 520 QNAHLAQH 527
>XP_005258967
          Length = 666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 469 QNAHLAQH 476
>XP_006723273
          Length = 717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 520 QNAHLAQH 527
>XP_005258616
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 236 QNAHLAQH 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 432 QNAGLAQH 439
>XP_005258615
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 280 QNAHLAQH 287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 476 QNAGLAQH 483
>XP_005274250
          Length = 2390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1102 ALLAQHA 1108
>XP_006718734
          Length = 2390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1102 ALLAQHA 1108
>XP_006718733
          Length = 2390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1102 ALLAQHA 1108
>XP_005274249
          Length = 2390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1102 ALLAQHA 1108
>XP_006718732
          Length = 2397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    ALLAQHS 9
            ALLAQH+
Sbjct: 1109 ALLAQHA 1115
>NP_001153332
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 279 QNAHLAQH 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 475 QNAGLAQH 482
>NP_001153333
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 279 QNAHLAQH 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ENALLAQH 8
           +NA LAQH
Sbjct: 475 QNAGLAQH 482
>NP_001269973
          Length = 2083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1770 NAILKQHT 1777
>NP_003156
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ENALLAQ 7
           +NALLAQ
Sbjct: 197 DNALLAQ 203
>NP_653267
          Length = 4753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ENALLAQHS 9
            +N LLA HS
Sbjct: 3498 KNPLLATHS 3506
>NP_055805
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1723 NAILKQHT 1730
>NP_001269972
          Length = 2049

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1736 NAILKQHT 1743
>NP_919277
          Length = 2083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1723 NAILKQHT 1730
>XP_005267555
          Length = 1325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NALLAQHS 9
           NA+L QH+
Sbjct: 964 NAILKQHT 971
>XP_006720166
          Length = 2083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1770 NAILKQHT 1777
>XP_005267550
          Length = 2084

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1723 NAILKQHT 1730
>XP_005267549
          Length = 2130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1770 NAILKQHT 1777
>XP_005267548
          Length = 2131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 1770 NAILKQHT 1777
>XP_006720165
          Length = 2542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 2229 NAILKQHT 2236
>XP_006720164
          Length = 2542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 2229 NAILKQHT 2236
>XP_006720163
          Length = 2543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 2182 NAILKQHT 2189
>XP_006720162
          Length = 2589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 2229 NAILKQHT 2236
>XP_006720161
          Length = 2590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    NALLAQHS 9
            NA+L QH+
Sbjct: 2229 NAILKQHT 2236
>NP_001027392
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ENALLAQ 7
           +NALLAQ
Sbjct: 197 DNALLAQ 203
>NP_001258625
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3 ALLAQHS 9
         ALLA HS
Sbjct: 2 ALLAMHS 8
>NP_001258627
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3 ALLAQHS 9
         ALLA HS
Sbjct: 2 ALLAMHS 8
>NP_004290
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3 ALLAQHS 9
         ALLA HS
Sbjct: 2 ALLAMHS 8
>NP_001258628
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3 ALLAQHS 9
         ALLA HS
Sbjct: 2 ALLAMHS 8
>NP_443723
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ENALLAQHS 9
            EN L+++H+
Sbjct: 1220 ENTLVSEHA 1228
>NP_001258626
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3 ALLAQHS 9
         ALLA HS
Sbjct: 2 ALLAMHS 8
>NP_004201
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENALLAQHS 9
           +N+L +QHS
Sbjct: 275 QNSLNSQHS 283
>NP_055836
          Length = 2723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENALLAQHS 9
           EN+LLA  S
Sbjct: 879 ENSLLADRS 887
>NP_006626
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   ENALLAQH 8
           EN  L QH
Sbjct: 179 ENCFLVQH 186
>XP_005258479
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   ENALLAQH 8
           EN  L QH
Sbjct: 138 ENCFLVQH 145
>XP_006723039
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   ENALLAQH 8
           EN  L QH
Sbjct: 179 ENCFLVQH 186
>XP_005270327
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENALLAQHS 9
           +N+L +QHS
Sbjct: 200 QNSLNSQHS 208
>XP_005270326
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ENALLAQHS 9
           +N+L +QHS
Sbjct: 258 QNSLNSQHS 266
>XP_006717590
          Length = 1397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ENALLAQHS 9
            EN L+++H+
Sbjct: 1276 ENTLVSEHA 1284
>XP_005248755
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENALLAQHS 9
           EN+LLA  S
Sbjct: 621 ENSLLADRS 629
>XP_005248754
          Length = 2583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ENALLAQHS 9
           EN+LLA  S
Sbjct: 739 ENSLLADRS 747
>NP_005459
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ALLAQHS 9
           ALL QHS
Sbjct: 609 ALLEQHS 615
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.113    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 451,402
Number of extensions: 696
Number of successful extensions: 61
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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