Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
NP_001077086                                                           16    5631
NP_055596                                                              16    5631
XP_006716555                                                           16    5631
XP_006716554                                                           16    5631
NP_057336                                                              16    7355
NP_036597                                                              16    7355
NP_852469                                                              16    7355
NP_005641                                                              16    7355
XP_006725846                                                           16    7355
XP_006725845                                                           16    7355
XP_006725844                                                           16    7355
XP_005277014                                                           16    7355
XP_005277013                                                           16    7355
XP_005277012                                                           16    7355
XP_005261781                                                           16    7355
XP_005261780                                                           16    7355
XP_006724377                                                           16    7355
XP_006724376                                                           16    7355
XP_005261779                                                           16    7355
XP_006712120                                                           16    7355
XP_005264512                                                           16    7355
XP_005264511                                                           16    7355
XP_006712119                                                           16    7355
XP_005264510                                                           16    7355
XP_006712118                                                           16    7355
XP_005264509                                                           16    7355
XP_005264508                                                           16    7355
XP_006712117                                                           16    7355
XP_005264507                                                           16    7355
XP_005264506                                                           16    7355
NP_065905                                                              15    9605
XP_006722578                                                           15    9605
XP_005266789                                                           15    9605
XP_006722577                                                           15    9605
XP_006722576                                                           15    9605
XP_005266788                                                           15    9605
XP_005266787                                                           15    9605



>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EMAADKRVG 9
           E AADKRVG
Sbjct: 513 ETAADKRVG 521





>NP_001077086
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  MAADKRV 8
          MAAD+RV
Sbjct: 53 MAADRRV 59





>NP_055596
          Length = 1594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  MAADKRV 8
          MAAD+RV
Sbjct: 53 MAADRRV 59





>XP_006716555
          Length = 1539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2 MAADKRV 8
         MAAD+RV
Sbjct: 1 MAADRRV 7





>XP_006716554
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  MAADKRV 8
          MAAD+RV
Sbjct: 53 MAADRRV 59





>NP_057336
          Length = 4857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4779 QYSSDKRVG 4787





>NP_036597
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EMAADKRV 8
           E+AADK++
Sbjct: 608 ELAADKKM 615





>NP_852469
          Length = 1938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>NP_005641
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006725846
          Length = 1938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006725845
          Length = 1949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006725844
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005277014
          Length = 1938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005277013
          Length = 1949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005277012
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005261781
          Length = 1938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005261780
          Length = 1949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006724377
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006724376
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_005261779
          Length = 1960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 888 MSADTRIG 895





>XP_006712120
          Length = 4812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4734 QYSSDKRVG 4742





>XP_005264512
          Length = 4840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4762 QYSSDKRVG 4770





>XP_005264511
          Length = 4847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4769 QYSSDKRVG 4777





>XP_006712119
          Length = 4851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4773 QYSSDKRVG 4781





>XP_005264510
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4783 QYSSDKRVG 4791





>XP_006712118
          Length = 4864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4786 QYSSDKRVG 4794





>XP_005264509
          Length = 4870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4792 QYSSDKRVG 4800





>XP_005264508
          Length = 4875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4797 QYSSDKRVG 4805





>XP_006712117
          Length = 4878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4800 QYSSDKRVG 4808





>XP_005264507
          Length = 4880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4802 QYSSDKRVG 4810





>XP_005264506
          Length = 4884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EMAADKRVG 9
            + ++DKRVG
Sbjct: 4806 QYSSDKRVG 4814





>NP_065905
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 499 MSADSRLG 506





>XP_006722578
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 143 MSADSRLG 150





>XP_005266789
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 499 MSADSRLG 506





>XP_006722577
          Length = 1043

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 499 MSADSRLG 506





>XP_006722576
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 499 MSADSRLG 506





>XP_005266788
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 475 MSADSRLG 482





>XP_005266787
          Length = 1216

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   MAADKRVG 9
           M+AD R+G
Sbjct: 499 MSADSRLG 506





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.126    0.326 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 359,031
Number of extensions: 328
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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