Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    2528
XP_006714104                                                           17    2528
XP_005265800                                                           17    2528
XP_006714103                                                           17    2528
XP_006714102                                                           17    2528
NP_001269618                                                           17    4312
NP_076982                                                              17    4312
NP_001269619                                                           17    4312
NP_001269617                                                           17    4312
XP_005252259                                                           17    4312
XP_006717345                                                           17    4312
XP_005252255                                                           17    4312
XP_005252253                                                           17    4312
XP_005252252                                                           17    4312
XP_005252250                                                           17    4312
NP_006005                                                              15    9605
>NP_006197
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           ELTVAA VL
Sbjct: 524 ELTVAAAVL 532
>XP_006714104
          Length = 832

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           ELTVAA VL
Sbjct: 549 ELTVAAAVL 557
>XP_005265800
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           ELTVAA VL
Sbjct: 524 ELTVAAAVL 532
>XP_006714103
          Length = 1111

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           ELTVAA VL
Sbjct: 546 ELTVAAAVL 554
>XP_006714102
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           ELTVAA VL
Sbjct: 549 ELTVAAAVL 557
>NP_001269618
          Length = 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 691 ELTVAAR 697
>NP_076982
          Length = 854

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 764 ELTVAAR 770
>NP_001269619
          Length = 786

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 696 ELTVAAR 702
>NP_001269617
          Length = 853

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 763 ELTVAAR 769
>XP_005252259
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 465 ELTVAAR 471
>XP_006717345
          Length = 781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 691 ELTVAAR 697
>XP_005252255
          Length = 786

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 696 ELTVAAR 702
>XP_005252253
          Length = 815

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 725 ELTVAAR 731
>XP_005252252
          Length = 816

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 726 ELTVAAR 732
>XP_005252250
          Length = 824

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   ELTVAAR 7
           ELTVAAR
Sbjct: 734 ELTVAAR 740
>NP_006005
          Length = 143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELTVAARVL 9
           +LTV+ R+L
Sbjct: 96  DLTVSGRIL 104
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.133    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 213,143
Number of extensions: 116
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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