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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1935
NP_671714                                                              18    1935
XP_006715890                                                           18    1935
XP_005250160                                                           18    1935
XP_005250159                                                           18    1935
NP_038477                                                              17    3301
XP_006719271                                                           17    3301
XP_005268661                                                           17    3301
XP_005268660                                                           17    3301
XP_005268659                                                           17    3301
XP_005268657                                                           17    3301
XP_006719270                                                           17    3301
XP_005268656                                                           17    3301
XP_005268654                                                           17    3301
XP_005268653                                                           17    3301
NP_006874                                                              16    5631
NP_000442                                                              16    5631
NP_006875                                                              16    5631
NP_001157150                                                           16    5631
NP_003021                                                              16    5631
XP_006713792                                                           16    5631
XP_006713791                                                           16    5631
XP_006713790                                                           16    5631
NP_001077415                                                           15    9605
NP_849188                                                              15    9605
NP_036367                                                              15    9605
XP_005265029                                                           15    9605
XP_005265028                                                           15    9605
XP_005265027                                                           15    9605
XP_005265026                                                           15    9605
XP_005265025                                                           15    9605
XP_005265024                                                           15    9605
XP_006713097                                                           15    9605
XP_005264468                                                           15    9605
XP_005264467                                                           15    9605
NP_653337                                                              15    9605

>NP_005742
          Length = 3907

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            ELSQRLV S
Sbjct: 1820 ELSQRLVRS 1828



>NP_671714
          Length = 3899

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            ELSQRLV S
Sbjct: 1820 ELSQRLVRS 1828



>XP_006715890
          Length = 3860

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            ELSQRLV S
Sbjct: 1773 ELSQRLVRS 1781



>XP_005250160
          Length = 3939

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            ELSQRLV S
Sbjct: 1852 ELSQRLVRS 1860



>XP_005250159
          Length = 3952

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            ELSQRLV S
Sbjct: 1852 ELSQRLVRS 1860



>NP_038477
          Length = 1905

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1523 ELEQRVIMS 1531



>XP_006719271
          Length = 1555

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1542 ELEQRVIMS 1550



>XP_005268661
          Length = 1657

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1275 ELEQRVIMS 1283



>XP_005268660
          Length = 1875

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1493 ELEQRVIMS 1501



>XP_005268659
          Length = 1894

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1512 ELEQRVIMS 1520



>XP_005268657
          Length = 1903

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1521 ELEQRVIMS 1529



>XP_006719270
          Length = 1903

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1521 ELEQRVIMS 1529



>XP_005268656
          Length = 1903

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1521 ELEQRVIMS 1529



>XP_005268654
          Length = 1923

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1542 ELEQRVIMS 1550



>XP_005268653
          Length = 1924

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ELSQRLVMS 9
            EL QR++MS
Sbjct: 1542 ELEQRVIMS 1550



>NP_006874
          Length = 225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 149 ELSQRLGLS 157



>NP_000442
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 149 ELSQRLGLS 157



>NP_006875
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 172 ELSQRLGLS 180



>NP_001157150
          Length = 319

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 172 ELSQRLGLS 180



>NP_003021
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 196 ELSQRLGLS 204



>XP_006713792
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ELSQRLVMS 9
          ELSQRL +S
Sbjct: 43 ELSQRLGLS 51



>XP_006713791
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  ELSQRLVMS 9
          ELSQRL +S
Sbjct: 43 ELSQRLGLS 51



>XP_006713790
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQRL +S
Sbjct: 196 ELSQRLGLS 204



>NP_001077415
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQR+ ++
Sbjct: 186 ELSQRIALT 194



>NP_849188
          Length = 2400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ELSQRLVMS 9
          ELSQR+ +S
Sbjct: 67 ELSQRVPLS 75



>NP_036367
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 515 LAQRLIMA 522



>XP_005265029
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 123 LAQRLIMA 130



>XP_005265028
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 123 LAQRLIMA 130



>XP_005265027
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 123 LAQRLIMA 130



>XP_005265026
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 260 LAQRLIMA 267



>XP_005265025
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 260 LAQRLIMA 267



>XP_005265024
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 515 LAQRLIMA 522



>XP_006713097
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LSQRLVMS 9
           L+QRL+M+
Sbjct: 515 LAQRLIMA 522



>XP_005264468
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQR+ ++
Sbjct: 213 ELSQRIALT 221



>XP_005264467
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQR+ ++
Sbjct: 242 ELSQRIALT 250



>NP_653337
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELSQRLVMS 9
           ELSQR+ ++
Sbjct: 284 ELSQRIALT 292



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.124    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 246,454
Number of extensions: 210
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)