Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              17    3301
NP_005913                                                              17    3301
XP_005267046                                                           17    3301
XP_005267045                                                           17    3301
NP_001165375                                                           16    7355
NP_055518                                                              16    7355
XP_005276812                                                           16    7355
XP_006713491                                                           16    7355
XP_005276811                                                           16    7355
XP_006713490                                                           16    7355
XP_005276810                                                           16    7355
XP_005276809                                                           16    7355
XP_006713489                                                           16    7355
XP_005276808                                                           16    7355
>NP_006715
          Length = 1558

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELSLLSIKQ 9
           E SLLSIKQ
Sbjct: 642 EPSLLSIKQ 650
>NP_005913
          Length = 1608

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELSLLSIKQ 9
           E SLLSIKQ
Sbjct: 642 EPSLLSIKQ 650
>XP_005267046
          Length = 1554

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELSLLSIKQ 9
           E SLLSIKQ
Sbjct: 642 EPSLLSIKQ 650
>XP_005267045
          Length = 1604

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELSLLSIKQ 9
           E SLLSIKQ
Sbjct: 642 EPSLLSIKQ 650
>NP_001165375
          Length = 1506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 738 LSLLSIK 744
>NP_055518
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_005276812
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_006713491
          Length = 1425

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 657 LSLLSIK 663
>XP_005276811
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_006713490
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_005276810
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_005276809
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_006713489
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
>XP_005276808
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LSLLSIK 8
           LSLLSIK
Sbjct: 739 LSLLSIK 745
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.128    0.279 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 270,781
Number of extensions: 257
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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