Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_001185763                                                           18    1135
NP_055459                                                              18    1135
XP_006726436                                                           18    1135
XP_006726410                                                           18    1135
XP_006711784                                                           18    1135
XP_006711719                                                           18    1135
XP_006711718                                                           18    1135
XP_006711717                                                           18    1135
XP_006711716                                                           18    1135
XP_006711715                                                           18    1135
XP_006711714                                                           18    1135
XP_006711713                                                           18    1135
XP_006711712                                                           18    1135
XP_006711711                                                           18    1135
XP_006711710                                                           18    1135
XP_006711709                                                           18    1135
XP_005277503                                                           18    1135
XP_005273038                                                           18    1135
XP_006711708                                                           18    1135
XP_005277500                                                           18    1135
XP_006711707                                                           18    1135
XP_005277499                                                           18    1135
XP_006711706                                                           18    1135
XP_006711705                                                           18    1135
XP_006711164                                                           18    1135
XP_005276114                                                           18    1135
XP_006710122                                                           18    1135
XP_006717822                                                           17    4312
XP_006717821                                                           17    4312
XP_005269749                                                           17    4312
XP_006717820                                                           17    4312
NP_065081                                                              17    4312
NP_065194                                                              16    5631
NP_001129243                                                           16    5631
NP_064569                                                              16    5631
NP_002942                                                              16    5631
XP_006723915                                                           16    5631
XP_006723914                                                           16    5631
XP_005260548                                                           16    5631
XP_006723913                                                           16    5631
XP_006723912                                                           16    5631
XP_006714991                                                           16    5631
XP_006714990                                                           16    5631
XP_005263972                                                           16    5631
XP_005263971                                                           16    5631
NP_588610                                                              16    5631
NP_079390                                                              15    9605
NP_056036                                                              15    9605
NP_005362                                                              15    9605
NP_079143                                                              15    9605
XP_006719673                                                           15    9605
XP_005269218                                                           15    9605
XP_005269217                                                           15    9605
XP_006719672                                                           15    9605
XP_005269215                                                           15    9605
XP_005268930                                                           15    9605
XP_006717799                                                           15    9605
XP_006717798                                                           15    9605
XP_006714564                                                           15    9605
XP_006714563                                                           15    9605
XP_005248434                                                           15    9605
XP_005248433                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2175 ELRTKVSKQ 2183
>NP_001185763
          Length = 2362

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2281 ELRTKVSKQ 2289
>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2281 ELRTKVSKQ 2289
>XP_006726436
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ELRIKVSKQ 9
          ELR KVSKQ
Sbjct: 59 ELRTKVSKQ 67
>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2022 ELRTKVSKQ 2030
>XP_006711784
          Length = 178

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ELRIKVSKQ 9
          ELR KVSKQ
Sbjct: 59 ELRTKVSKQ 67
>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2237 ELRTKVSKQ 2245
>XP_006711718
          Length = 1436

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 1288 ELRTKVSKQ 1296
>XP_006711717
          Length = 2385

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2237 ELRTKVSKQ 2245
>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2346 ELRTKVSKQ 2354
>XP_006711715
          Length = 2428

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2280 ELRTKVSKQ 2288
>XP_006711714
          Length = 2429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2281 ELRTKVSKQ 2289
>XP_006711713
          Length = 2432

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2284 ELRTKVSKQ 2292
>XP_006711712
          Length = 2473

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2325 ELRTKVSKQ 2333
>XP_006711711
          Length = 2482

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2334 ELRTKVSKQ 2342
>XP_006711710
          Length = 2494

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2346 ELRTKVSKQ 2354
>XP_006711709
          Length = 2495

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2347 ELRTKVSKQ 2355
>XP_005277503
          Length = 2498

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2444 ELRTKVSKQ 2452
>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2444 ELRTKVSKQ 2452
>XP_006711708
          Length = 2512

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2364 ELRTKVSKQ 2372
>XP_005277500
          Length = 2525

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2444 ELRTKVSKQ 2452
>XP_006711707
          Length = 2553

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2405 ELRTKVSKQ 2413
>XP_005277499
          Length = 2561

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2444 ELRTKVSKQ 2452
>XP_006711706
          Length = 2591

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2443 ELRTKVSKQ 2451
>XP_006711705
          Length = 2592

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2444 ELRTKVSKQ 2452
>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR KVSKQ
Sbjct: 2022 ELRTKVSKQ 2030
>XP_005276114
          Length = 134

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ELRIKVSKQ 9
          ELR KVSKQ
Sbjct: 29 ELRTKVSKQ 37
>XP_006710122
          Length = 126

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ELRIKVSKQ 9
          ELR KVSKQ
Sbjct: 59 ELRTKVSKQ 67
>XP_006717822
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+R+K+S Q
Sbjct: 600 EMRVKISPQ 608
>XP_006717821
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+R+K+S Q
Sbjct: 600 EMRVKISPQ 608
>XP_005269749
          Length = 901

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+R+K+S Q
Sbjct: 600 EMRVKISPQ 608
>XP_006717820
          Length = 949

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+R+K+S Q
Sbjct: 600 EMRVKISPQ 608
>NP_065081
          Length = 951

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+R+K+S Q
Sbjct: 600 EMRVKISPQ 608
>NP_065194
          Length = 1819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ELRIKVSKQ 9
           ELR++++KQ
Sbjct: 662 ELRMEIAKQ 670
>NP_001129243
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 332 ELRVKISTE 340
>NP_064569
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           EL++K+S Q
Sbjct: 541 ELKVKISPQ 549
>NP_002942
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 364 ELRVKISTE 372
>XP_006723915
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 380 ELRVKISTE 388
>XP_006723914
          Length = 631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 380 ELRVKISTE 388
>XP_005260548
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 364 ELRVKISTE 372
>XP_006723913
          Length = 647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 380 ELRVKISTE 388
>XP_006723912
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ELR+K+S +
Sbjct: 380 ELRVKISTE 388
>XP_006714991
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+RI VS+Q
Sbjct: 103 EVRINVSRQ 111
>XP_006714990
          Length = 941

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+RI VS+Q
Sbjct: 103 EVRINVSRQ 111
>XP_005263972
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           EL++K+S Q
Sbjct: 541 ELKVKISPQ 549
>XP_005263971
          Length = 796

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           EL++K+S Q
Sbjct: 541 ELKVKISPQ 549
>NP_588610
          Length = 842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           E+RI VS+Q
Sbjct: 103 EVRINVSRQ 111
>NP_079390
          Length = 2479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ELRIKVSK 8
            EL+++VSK
Sbjct: 1147 ELKVEVSK 1154
>NP_056036
          Length = 1577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ++ IKVSKQ
Sbjct: 832 QMVIKVSKQ 840
>NP_005362
          Length = 276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ELRIKVS 7
           E+R+KVS
Sbjct: 107 EIRVKVS 113
>NP_079143
          Length = 1822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR+K+ ++
Sbjct: 1343 ELRVKIKEE 1351
>XP_006719673
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELRIKVSK 8
           EL+++VSK
Sbjct: 665 ELKVEVSK 672
>XP_005269218
          Length = 2009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELRIKVSK 8
           EL+++VSK
Sbjct: 677 ELKVEVSK 684
>XP_005269217
          Length = 2353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ELRIKVSK 8
            EL+++VSK
Sbjct: 1178 ELKVEVSK 1185
>XP_006719672
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ELRIKVSK 8
            EL+++VSK
Sbjct: 1178 ELKVEVSK 1185
>XP_005269215
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ELRIKVSK 8
            EL+++VSK
Sbjct: 1178 ELKVEVSK 1185
>XP_005268930
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ELRIKVS 7
          E+R+KVS
Sbjct: 64 EIRVKVS 70
>XP_006717799
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ++ IKVSKQ
Sbjct: 832 QMVIKVSKQ 840
>XP_006717798
          Length = 1534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELRIKVSKQ 9
           ++ IKVSKQ
Sbjct: 832 QMVIKVSKQ 840
>XP_006714564
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR+K+ ++
Sbjct: 1343 ELRVKIKEE 1351
>XP_006714563
          Length = 1766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR+K+ ++
Sbjct: 1286 ELRVKIKEE 1294
>XP_005248434
          Length = 1818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR+K+ ++
Sbjct: 1338 ELRVKIKEE 1346
>XP_005248433
          Length = 1823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    ELRIKVSKQ 9
            ELR+K+ ++
Sbjct: 1343 ELRVKIKEE 1351
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.128    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 326,554
Number of extensions: 417
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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