Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1135
NP_005913                                                              18    1135
XP_005267046                                                           18    1135
XP_005267045                                                           18    1135
NP_001242910                                                           17    4312
NP_570968                                                              17    4312
NP_001242909                                                           17    4312
NP_001242908                                                           17    4312
NP_001242907                                                           17    4312
XP_006711235                                                           17    4312
NP_056276                                                              16    5631
XP_005258298                                                           16    5631
XP_006722500                                                           16    5631
XP_006722499                                                           16    5631
XP_003960384                                                           16    7355
XP_003118572                                                           16    7355
XP_003119970                                                           16    7355
NP_006289                                                              15    9605
NP_001265048                                                           15    9605
NP_001072990                                                           15    9605
NP_001257943                                                           15    9605
NP_001139187                                                           15    9605
NP_004977                                                              15    9605
XP_006720204                                                           15    9605
XP_006720203                                                           15    9605
XP_006720202                                                           15    9605
XP_006720201                                                           15    9605
XP_006716050                                                           15    9605
XP_005249439                                                           15    9605
NP_443089                                                              15    9605
NP_001072989                                                           15    9605
>NP_006715
          Length = 1558

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQTLISQS 9
            EL+TLISQS
Sbjct: 1226 ELRTLISQS 1234
>NP_005913
          Length = 1608

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQTLISQS 9
            EL+TLISQS
Sbjct: 1276 ELRTLISQS 1284
>XP_005267046
          Length = 1554

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQTLISQS 9
            EL+TLISQS
Sbjct: 1222 ELRTLISQS 1230
>XP_005267045
          Length = 1604

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQTLISQS 9
            EL+TLISQS
Sbjct: 1272 ELRTLISQS 1280
>NP_001242910
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 259 QLQTLIAQT 267
>NP_570968
          Length = 395

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 279 QLQTLIAQT 287
>NP_001242909
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 259 QLQTLIAQT 267
>NP_001242908
          Length = 395

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 279 QLQTLIAQT 287
>NP_001242907
          Length = 395

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 279 QLQTLIAQT 287
>XP_006711235
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ELQTLISQS 9
           +LQTLI+Q+
Sbjct: 259 QLQTLIAQT 267
>NP_056276
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELQTLISQS 9
           ELQTL++ S
Sbjct: 857 ELQTLLTNS 865
>XP_005258298
          Length = 1091

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELQTLISQS 9
           ELQTL++ S
Sbjct: 637 ELQTLLTNS 645
>XP_006722500
          Length = 1218

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELQTLISQS 9
           ELQTL++ S
Sbjct: 857 ELQTLLTNS 865
>XP_006722499
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELQTLISQS 9
           ELQTL++ S
Sbjct: 857 ELQTLLTNS 865
>XP_003960384
          Length = 884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTLIS+
Sbjct: 431 KLQTLISE 438
>XP_003118572
          Length = 884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTLIS+
Sbjct: 431 KLQTLISE 438
>XP_003119970
          Length = 884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTLIS+
Sbjct: 431 KLQTLISE 438
>NP_006289
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           ELQTL+ +
Sbjct: 106 ELQTLVKE 113
>NP_001265048
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           ELQTL+ +
Sbjct: 106 ELQTLVKE 113
>NP_001072990
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>NP_001257943
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>NP_001139187
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           E QTL+SQ
Sbjct: 492 ESQTLLSQ 499
>NP_004977
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>XP_006720204
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>XP_006720203
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>XP_006720202
          Length = 1329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>XP_006720201
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
>XP_006716050
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           E QTL+SQ
Sbjct: 492 ESQTLLSQ 499
>XP_005249439
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           ELQTL+ +
Sbjct: 106 ELQTLVKE 113
>NP_443089
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELQTLISQ 8
           ELQ L+SQ
Sbjct: 356 ELQDLLSQ 363
>NP_001072989
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELQTLISQ 8
           +LQTL+S+
Sbjct: 716 KLQTLVSE 723
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.115    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 334,625
Number of extensions: 567
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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