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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_620055                                                              17    3301
NP_060214                                                              17    3301
NP_620056                                                              17    3301
NP_620057                                                              17    3301
XP_005271023                                                           17    3301
XP_006710772                                                           17    3301
XP_005271021                                                           17    3301
XP_005271020                                                           17    3301
NP_065944                                                              16    5631
NP_001161842                                                           16    5631
NP_001189479                                                           16    5631
NP_055595                                                              16    5631
XP_006715498                                                           16    5631
XP_006715497                                                           16    5631
XP_006715496                                                           16    5631
XP_006715348                                                           16    5631
XP_005249560                                                           16    5631
NP_055022                                                              16    5631
NP_060404                                                              16    7355
NP_001036182                                                           16    7355
NP_149098                                                              16    7355
XP_005248786                                                           16    7355
NP_008880                                                              15    9605
NP_001258963                                                           15    9605
NP_001120868                                                           15    9605
NP_689593                                                              15    9605
XP_006722914                                                           15    9605
XP_005271219                                                           15    9605
XP_005271218                                                           15    9605
NP_001127925                                                           15    9605

>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQAYPALM 9
            ELQAYPAL+
Sbjct: 3438 ELQAYPALV 3446



>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ELQAYPALM 9
            ELQAYPAL+
Sbjct: 3438 ELQAYPALV 3446



>NP_620055
          Length = 558

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 324 ELQAYP 329



>NP_060214
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 341 ELQAYP 346



>NP_620056
          Length = 544

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 341 ELQAYP 346



>NP_620057
          Length = 555

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 341 ELQAYP 346



>XP_005271023
          Length = 418

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 341 ELQAYP 346



>XP_006710772
          Length = 447

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 341 ELQAYP 346



>XP_005271021
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 219 ELQAYP 224



>XP_005271020
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELQAYP 6
           ELQAYP
Sbjct: 219 ELQAYP 224



>NP_065944
          Length = 1701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ELQAYPALM 9
           E+  YPA+M
Sbjct: 609 EVMEYPAIM 617



>NP_001161842
          Length = 1782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAYPALM 9
           QAYP+L+
Sbjct: 661 QAYPSLL 667



>NP_001189479
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQAYP L
Sbjct: 109 LQAYPLL 115



>NP_055595
          Length = 1698

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAYPALM 9
           QAYP+L+
Sbjct: 577 QAYPSLL 583



>XP_006715498
          Length = 378

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQAYP L
Sbjct: 109 LQAYPLL 115



>XP_006715497
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQAYP L
Sbjct: 109 LQAYPLL 115



>XP_006715496
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQAYP L
Sbjct: 109 LQAYPLL 115



>XP_006715348
          Length = 1734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAYPALM 9
           QAYP+L+
Sbjct: 609 QAYPSLL 615



>XP_005249560
          Length = 1750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   QAYPALM 9
           QAYP+L+
Sbjct: 629 QAYPSLL 635



>NP_055022
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           L AYPAL
Sbjct: 462 LSAYPAL 468



>NP_060404
          Length = 1821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    ELQAYP 6
            +LQAYP
Sbjct: 1189 DLQAYP 1194



>NP_001036182
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ELQAYPALM 9
           ELQ  PAL+
Sbjct: 188 ELQTKPALL 196



>NP_149098
          Length = 387

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ELQAYPALM 9
           ELQ  PAL+
Sbjct: 267 ELQTKPALL 275



>XP_005248786
          Length = 1820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    ELQAYP 6
            +LQAYP
Sbjct: 1188 DLQAYP 1193



>NP_008880
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ YPA+
Sbjct: 183 LQEYPAI 189



>NP_001258963
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ YPA+
Sbjct: 194 LQEYPAI 200



>NP_001120868
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ YPA+
Sbjct: 180 LQEYPAI 186



>NP_689593
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ+YP L
Sbjct: 304 LQSYPGL 310



>XP_006722914
          Length = 566

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ YPA+
Sbjct: 183 LQEYPAI 189



>XP_005271219
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ+YP L
Sbjct: 410 LQSYPGL 416



>XP_005271218
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LQAYPAL 8
           LQ+YP L
Sbjct: 443 LQSYPGL 449



>NP_001127925
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAYPALM 9
           LQA PAL+
Sbjct: 717 LQATPALL 724



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.131    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 518,675
Number of extensions: 553
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)