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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_056342                                                              17    4312
XP_005267654                                                           17    4312
NP_060045                                                              16    5631
XP_005256627                                                           16    5631
XP_006721558                                                           16    5631
XP_006721557                                                           16    5631
XP_006721556                                                           16    5631
XP_005256626                                                           16    5631
XP_005270208                                                           16    5631
XP_005270207                                                           16    5631
XP_005270206                                                           16    5631
NP_077302                                                              16    5631
NP_001243757                                                           16    7355
NP_001269255                                                           16    7355
NP_001243756                                                           16    7355
NP_061159                                                              16    7355
XP_005256628                                                           16    7355
XP_005254625                                                           16    7355
XP_005254624                                                           16    7355
XP_006710433                                                           16    7355
XP_006710432                                                           16    7355
XP_006710431                                                           16    7355
XP_006710430                                                           16    7355
XP_006710429                                                           16    7355
NP_612486                                                              15    9605
NP_001013860                                                           15    9605
XP_006721205                                                           15    9605
XP_005255864                                                           15    9605
XP_006721204                                                           15    9605
XP_006721203                                                           15    9605
XP_006721202                                                           15    9605
XP_006721201                                                           15    9605
XP_005254235                                                           15    9605
XP_005254233                                                           15    9605
XP_005254234                                                           15    9605
XP_006714554                                                           15    9605
XP_005248410                                                           15    9605
XP_006714553                                                           15    9605
XP_005248407                                                           15    9605
XP_005248404                                                           15    9605
XP_005248403                                                           15    9605
XP_006714552                                                           15    9605
XP_005248402                                                           15    9605

>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2446 ELDELALRA 2454



>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 1098 ELDELALRA 1106



>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2098 ELDELALRA 2106



>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2440 ELDELALRA 2448



>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2446 ELDELALRA 2454



>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2446 ELDELALRA 2454



>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELDGLALRA 9
            ELD LALRA
Sbjct: 2446 ELDELALRA 2454



>NP_056342
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ELDGLALR 8
           E++GLALR
Sbjct: 295 EINGLALR 302



>XP_005267654
          Length = 212

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELDGLALRA 9
           EL+GL +RA
Sbjct: 176 ELEGLRMRA 184



>NP_060045
          Length = 1419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 704 MDGLAIRS 711




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELDGLA 6
            ELDGLA
Sbjct: 1282 ELDGLA 1287



>XP_005256627
          Length = 899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 704 MDGLAIRS 711



>XP_006721558
          Length = 909

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 704 MDGLAIRS 711



>XP_006721557
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 704 MDGLAIRS 711



>XP_006721556
          Length = 1357

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 704 MDGLAIRS 711




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELDGLA 6
            ELDGLA
Sbjct: 1220 ELDGLA 1225



>XP_005256626
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LDGLALRA 9
           +DGLA+R+
Sbjct: 673 MDGLAIRS 680




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    ELDGLA 6
            ELDGLA
Sbjct: 1251 ELDGLA 1256



>XP_005270208
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDGLALR 8
           +DGLALR
Sbjct: 153 VDGLALR 159



>XP_005270207
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDGLALR 8
           +DGLALR
Sbjct: 153 VDGLALR 159



>XP_005270206
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDGLALR 8
           +DGLALR
Sbjct: 240 VDGLALR 246



>NP_077302
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LDGLALR 8
           +DGLALR
Sbjct: 153 VDGLALR 159



>NP_001243757
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELDGLA 6
           ELDGLA
Sbjct: 374 ELDGLA 379



>NP_001269255
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELDGLA 6
           ELDGLA
Sbjct: 193 ELDGLA 198



>NP_001243756
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELDGLA 6
           ELDGLA
Sbjct: 374 ELDGLA 379



>NP_061159
          Length = 1361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELDGLALRA 9
           E+DG+ +RA
Sbjct: 481 EIDGVDMRA 489



>XP_005256628
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELDGLA 6
           ELDGLA
Sbjct: 374 ELDGLA 379



>XP_005254625
          Length = 1361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELDGLALRA 9
           E+DG+ +RA
Sbjct: 481 EIDGVDMRA 489



>XP_005254624
          Length = 1361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELDGLALRA 9
           E+DG+ +RA
Sbjct: 481 EIDGVDMRA 489



>XP_006710433
          Length = 1169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DGLALRA 9
           DGL LRA
Sbjct: 107 DGLGLRA 113



>XP_006710432
          Length = 1202

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DGLALRA 9
           DGL LRA
Sbjct: 107 DGLGLRA 113



>XP_006710431
          Length = 1205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DGLALRA 9
           DGL LRA
Sbjct: 107 DGLGLRA 113



>XP_006710430
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DGLALRA 9
           DGL LRA
Sbjct: 107 DGLGLRA 113



>XP_006710429
          Length = 1238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DGLALRA 9
           DGL LRA
Sbjct: 107 DGLGLRA 113



>NP_612486
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELDGLAL 7
           EL+GLAL
Sbjct: 597 ELNGLAL 603



>NP_001013860
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 483 LDGLAL 488



>XP_006721205
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 483 LDGLAL 488



>XP_005255864
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 447 LDGLAL 452



>XP_006721204
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 447 LDGLAL 452



>XP_006721203
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 483 LDGLAL 488



>XP_006721202
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 483 LDGLAL 488



>XP_006721201
          Length = 1430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDGLAL 7
           LDGLAL
Sbjct: 483 LDGLAL 488



>XP_005254235
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELDGLAL 7
           EL+GLAL
Sbjct: 598 ELNGLAL 604



>XP_005254233
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELDGLAL 7
           EL+GLAL
Sbjct: 598 ELNGLAL 604



>XP_005254234
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELDGLAL 7
           EL+GLAL
Sbjct: 598 ELNGLAL 604



>XP_006714554
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LDGLALRA 9
           LDG +LRA
Sbjct: 868 LDGKSLRA 875



>XP_005248410
          Length = 2132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 1558 LDGKSLRA 1565



>XP_006714553
          Length = 2792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2677 LDGKSLRA 2684



>XP_005248407
          Length = 3208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2634 LDGKSLRA 2641



>XP_005248404
          Length = 3250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2676 LDGKSLRA 2683



>XP_005248403
          Length = 3250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2676 LDGKSLRA 2683



>XP_006714552
          Length = 3251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2677 LDGKSLRA 2684



>XP_005248402
          Length = 3251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LDGLALRA 9
            LDG +LRA
Sbjct: 2677 LDGKSLRA 2684



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.143    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,295
Number of extensions: 661
Number of successful extensions: 53
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)