Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              17    2528
NP_444254                                                              17    2528
NP_444253                                                              17    2528
NP_444255                                                              17    2528
NP_573572                                                              17    2528
NP_001106962                                                           17    2528
XP_006724686                                                           17    2528
XP_005262147                                                           17    2528
XP_005262146                                                           17    2528
XP_005262145                                                           17    2528
XP_005262144                                                           17    2528
XP_005247551                                                           17    2528
XP_005247550                                                           17    2528
XP_006713712                                                           17    2528
XP_005247549                                                           17    2528
NP_001035203                                                           17    4312
NP_074035                                                              17    4312
NP_001035202                                                           17    4312
NP_002465                                                              17    4312
NP_064592                                                              16    7355
NP_001278413                                                           16    7355
NP_001010895                                                           16    7355
NP_004354                                                              16    7355
NP_003001                                                              16    7355
NP_001268364                                                           16    7355
NP_001077415                                                           16    7355
NP_699195                                                              16    7355
NP_055668                                                              16    7355
NP_076951                                                              16    7355
XP_005258472                                                           16    7355
XP_006721677                                                           16    7355
XP_006721676                                                           16    7355
XP_005256812                                                           16    7355
XP_006721631                                                           16    7355
XP_005256810                                                           16    7355
XP_005265535                                                           16    7355
XP_005264468                                                           16    7355
XP_005264467                                                           16    7355
NP_653337                                                              16    7355
NP_001091979                                                           16    7355
NP_689836                                                              15    9605
NP_001139206                                                           15    9605
NP_001163873                                                           15    9605
NP_001244255                                                           15    9605
NP_001155                                                              15    9605
NP_001244250                                                           15    9605
NP_001244252                                                           15    9605
NP_663722                                                              15    9605
NP_001244249                                                           15    9605
NP_001244254                                                           15    9605
NP_001244248                                                           15    9605
NP_060275                                                              15    9605
XP_005259081                                                           15    9605
XP_006723314                                                           15    9605
XP_005259080                                                           15    9605
XP_006723313                                                           15    9605
XP_006718279                                                           15    9605
XP_006718278                                                           15    9605
XP_006718277                                                           15    9605
XP_006718276                                                           15    9605
XP_006718275                                                           15    9605
XP_006718274                                                           15    9605
XP_006718273                                                           15    9605
XP_006718272                                                           15    9605
>NP_444256
          Length = 1794

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1311 ELATCRSTS 1319
>NP_444254
          Length = 1845

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1311 ELATCRSTS 1319
>NP_444253
          Length = 1914

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1380 ELATCRSTS 1388
>NP_444255
          Length = 1863

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1380 ELATCRSTS 1388
>NP_573572
          Length = 675

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 148 ELATARSTN 156
>NP_001106962
          Length = 1084

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 557 ELATARSTN 565
>XP_006724686
          Length = 675

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 148 ELATARSTN 156
>XP_005262147
          Length = 675

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 148 ELATARSTN 156
>XP_005262146
          Length = 1084

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 557 ELATARSTN 565
>XP_005262145
          Length = 1084

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 557 ELATARSTN 565
>XP_005262144
          Length = 1084

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   ELATGRSTS 9
           ELAT RST+
Sbjct: 557 ELATARSTN 565
>XP_005247551
          Length = 1855

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1321 ELATCRSTS 1329
>XP_005247550
          Length = 1856

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1390 ELATCRSTS 1398
>XP_006713712
          Length = 1923

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1390 ELATCRSTS 1398
>XP_005247549
          Length = 1924

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RSTS
Sbjct: 1390 ELATCRSTS 1398
>NP_001035203
          Length = 1979

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RST+
Sbjct: 1779 ELATERSTA 1787
>NP_074035
          Length = 1938

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RST+
Sbjct: 1772 ELATERSTA 1780
>NP_001035202
          Length = 1945

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RST+
Sbjct: 1779 ELATERSTA 1787
>NP_002465
          Length = 1972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ELATGRSTS 9
            ELAT RST+
Sbjct: 1772 ELATERSTA 1780
>NP_064592
          Length = 1561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 360 ELATGR 365
>NP_001278413
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LATGR+ S
Sbjct: 660 LATGRNNS 667
>NP_001010895
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 360 ELATGR 365
>NP_004354
          Length = 702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LATGR+ S
Sbjct: 660 LATGRNNS 667
>NP_003001
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 299 ELATGR 304
>NP_001268364
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 310 ELATGR 315
>NP_001077415
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LATGRSTS 9
          +ATG+ST+
Sbjct: 83 MATGKSTA 90
>NP_699195
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELATGRS 7
           +LATGRS
Sbjct: 141 KLATGRS 147
>NP_055668
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ TGR+T
Sbjct: 407 EMGTGRAT 414
>NP_076951
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 100 ELATGR 105
>XP_005258472
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LATGR+ S
Sbjct: 378 LATGRNNS 385
>XP_006721677
          Length = 1028

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ TGR+T
Sbjct: 429 EMGTGRAT 436
>XP_006721676
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ TGR+T
Sbjct: 429 EMGTGRAT 436
>XP_005256812
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 153 ELATGR 158
>XP_006721631
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 181 ELATGR 186
>XP_005256810
          Length = 281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 181 ELATGR 186
>XP_005265535
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ELATGR 6
           ELATGR
Sbjct: 100 ELATGR 105
>XP_005264468
          Length = 370

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LATGRSTS 9
           +ATG+ST+
Sbjct: 110 MATGKSTA 117
>XP_005264467
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LATGRSTS 9
          +ATG+ST+
Sbjct: 68 MATGKSTA 75
>NP_653337
          Length = 441

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LATGRSTS 9
           +ATG+ST+
Sbjct: 110 MATGKSTA 117
>NP_001091979
          Length = 1006

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ TGR+T
Sbjct: 407 EMGTGRAT 414
>NP_689836
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ATG+ T
Sbjct: 459 EIATGQGT 466
>NP_001139206
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ATG+ T
Sbjct: 417 EIATGQGT 424
>NP_001163873
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           E+ATG+ T
Sbjct: 459 EIATGQGT 466
>NP_001244255
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 125 ELAPGRSS 132
>NP_001155
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 384 ELAPGRSS 391
>NP_001244250
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 125 ELAPGRSS 132
>NP_001244252
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 164 ELAPGRSS 171
>NP_663722
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 384 ELAPGRSS 391
>NP_001244249
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 125 ELAPGRSS 132
>NP_001244254
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 149 ELAPGRSS 156
>NP_001244248
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 164 ELAPGRSS 171
>NP_060275
          Length = 963

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LAT RST+
Sbjct: 165 LATARSTA 172
>XP_005259081
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LAT RST+
Sbjct: 266 LATARSTA 273
>XP_006723314
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LAT RST+
Sbjct: 266 LATARSTA 273
>XP_005259080
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LAT RST+
Sbjct: 266 LATARSTA 273
>XP_006723313
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATGRSTS 9
           LAT RST+
Sbjct: 266 LATARSTA 273
>XP_006718279
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 476 ELAPGRSS 483
>XP_006718278
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 476 ELAPGRSS 483
>XP_006718277
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 481 ELAPGRSS 488
>XP_006718276
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 384 ELAPGRSS 391
>XP_006718275
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 481 ELAPGRSS 488
>XP_006718274
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 389 ELAPGRSS 396
>XP_006718273
          Length = 898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 476 ELAPGRSS 483
>XP_006718272
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELATGRST 8
           ELA GRS+
Sbjct: 481 ELAPGRSS 488
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.107    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 424,186
Number of extensions: 443
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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