Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_055335                                                              17    3301
NP_001099008                                                           17    3301
XP_005256470                                                           17    3301
NP_002664                                                              17    4312
NP_001123554                                                           17    4312
XP_006713269                                                           17    4312
NP_079408                                                              16    5631
NP_001073883                                                           16    5631
NP_001186948                                                           16    5631
NP_851853                                                              16    5631
NP_872588                                                              16    5631
NP_000904                                                              16    5631
XP_006723863                                                           16    5631
XP_005260263                                                           16    5631
XP_006723862                                                           16    5631
XP_005267748                                                           16    5631
XP_006714089                                                           16    5631
XP_006714088                                                           16    5631
XP_005262715                                                           16    5631
NP_002461                                                              16    7355
NP_694551                                                              16    7355
NP_055950                                                              16    7355
XP_006726466                                                           16    7355
XP_006721591                                                           16    7355
XP_005250292                                                           16    7355
XP_006712969                                                           16    7355
XP_005275995                                                           16    7355
NP_620688                                                              15    9605
NP_776297                                                              15    9605
NP_001230301                                                           15    9605
NP_001820                                                              15    9605
NP_001230303                                                           15    9605
NP_005537                                                              15    9605
NP_001243000                                                           15    9605
NP_036329                                                              15    9605
NP_001135741                                                           15    9605
NP_000812                                                              15    9605
NP_542165                                                              15    9605
NP_899662                                                              15    9605
NP_002886                                                              15    9605
NP_005795                                                              15    9605
NP_001271204                                                           15    9605
NP_037511                                                              15    9605
NP_004631                                                              15    9605
NP_001138490                                                           15    9605
XP_006723905                                                           15    9605
XP_005257603                                                           15    9605
XP_006722058                                                           15    9605
XP_005257602                                                           15    9605
XP_005254929                                                           15    9605
XP_006718884                                                           15    9605
XP_006718882                                                           15    9605
XP_006718879                                                           15    9605
XP_006717146                                                           15    9605
XP_005266132                                                           15    9605
XP_006717095                                                           15    9605
XP_006717094                                                           15    9605
XP_005251923                                                           15    9605
XP_005262783                                                           15    9605
XP_005264316                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4451 ELALRRGLQ 4459
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4467 ELALRRGLQ 4475
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4468 ELALRRGLQ 4476
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4499 ELALRRGLQ 4507
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4523 ELALRRGLQ 4531
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4522 ELALRRGLQ 4530
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4522 ELALRRGLQ 4530
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4522 ELALRRGLQ 4530
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ELALRRDLQ 9
            ELALRR LQ
Sbjct: 4523 ELALRRGLQ 4531
>NP_055335
          Length = 1328

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ELALRRDLQ 9
           E ALRRD Q
Sbjct: 817 EKALRRDFQ 825
>NP_001099008
          Length = 1332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ELALRRDLQ 9
           E ALRRD Q
Sbjct: 817 EKALRRDFQ 825
>XP_005256470
          Length = 1120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ELALRRDLQ 9
           E ALRRD Q
Sbjct: 817 EKALRRDFQ 825
>NP_002664
          Length = 2135

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L LRRDLQ
Sbjct: 231 LFLRRDLQ 238
>NP_001123554
          Length = 2135

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L LRRDLQ
Sbjct: 231 LFLRRDLQ 238
>XP_006713269
          Length = 2052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L LRRDLQ
Sbjct: 148 LFLRRDLQ 155
>NP_079408
          Length = 1342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L +RRDLQ
Sbjct: 750 LEMRRDLQ 757
>NP_001073883
          Length = 2028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRDL+
Sbjct: 798 ALRRDLE 804
>NP_001186948
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 338 ALRRDVQ 344
>NP_851853
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ELALRRDLQ 9
          +L LRR+LQ
Sbjct: 6  DLELRRELQ 14
>NP_872588
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 338 ALRRDVQ 344
>NP_000904
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 338 ALRRDVQ 344
>XP_006723863
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 257 ALRRDVQ 263
>XP_005260263
          Length = 365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 333 ALRRDVQ 339
>XP_006723862
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRD+Q
Sbjct: 338 ALRRDVQ 344
>XP_005267748
          Length = 1535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           ALRRDL+
Sbjct: 798 ALRRDLE 804
>XP_006714089
          Length = 1281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L +RRDLQ
Sbjct: 750 LEMRRDLQ 757
>XP_006714088
          Length = 1283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L +RRDLQ
Sbjct: 691 LEMRRDLQ 698
>XP_005262715
          Length = 1320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L +RRDLQ
Sbjct: 728 LEMRRDLQ 735
>NP_002461
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LALRRDLQ 9
            L LRRDL+
Sbjct: 1173 LKLRRDLE 1180
>NP_694551
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LRRDLQ 9
           LRRDLQ
Sbjct: 464 LRRDLQ 469
>NP_055950
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LALRRDLQ 9
           ++LRRDL+
Sbjct: 433 ISLRRDLE 440
>XP_006726466
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELALRRD 7
           ELALRR+
Sbjct: 130 ELALRRE 136
>XP_006721591
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LALRRDLQ 9
            L LRRDL+
Sbjct: 1173 LKLRRDLE 1180
>XP_005250292
          Length = 1654

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LALRRDLQ 9
          ++LRRDL+
Sbjct: 75 ISLRRDLE 82
>XP_006712969
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELALRRD 7
           ELALRR+
Sbjct: 130 ELALRRE 136
>XP_005275995
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELALRRD 7
           ELALRR+
Sbjct: 130 ELALRRE 136
>NP_620688
          Length = 1095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L LRRDL+
Sbjct: 94  LQLRRDLR 101
>NP_776297
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 707 ALRRDL 712
>NP_001230301
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 680 ALRRDL 685
>NP_001820
          Length = 818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 707 ALRRDL 712
>NP_001230303
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 680 ALRRDL 685
>NP_005537
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ELALRRD 7
           ELALRR+
Sbjct: 189 ELALRRN 195
>NP_001243000
          Length = 5207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LALRRDL 8
            LAL+RDL
Sbjct: 4788 LALQRDL 4794
>NP_036329
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELALRRDL 8
           ++ALR+DL
Sbjct: 867 KIALRKDL 874
>NP_001135741
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELALRRDL 8
           ELAL +DL
Sbjct: 551 ELALEQDL 558
>NP_000812
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELALRRDL 8
           ELAL +DL
Sbjct: 608 ELALEQDL 615
>NP_542165
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELALRRDLQ 9
           +L +RRD+Q
Sbjct: 204 QLDMRRDVQ 212
>NP_899662
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           +LRRD+Q
Sbjct: 631 SLRRDMQ 637
>NP_002886
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           +LRRD+Q
Sbjct: 631 SLRRDMQ 637
>NP_005795
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELALRRDLQ 9
           +L +RRD+Q
Sbjct: 203 QLDMRRDVQ 211
>NP_001271204
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ELALRRDLQ 9
          E+ +RR+LQ
Sbjct: 9  EIKVRRELQ 17
>NP_037511
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 144 ALRRDL 149
>NP_004631
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELALRRDLQ 9
           +L +RRD+Q
Sbjct: 204 QLDMRRDVQ 212
>NP_001138490
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LALRRD 7
          LALRRD
Sbjct: 45 LALRRD 50
>XP_006723905
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ALRRDLQ 9
           +LRRD+Q
Sbjct: 459 SLRRDMQ 465
>XP_005257603
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LALRRDL 8
            LAL+RDL
Sbjct: 4837 LALQRDL 4843
>XP_006722058
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LALRRDL 8
            LAL+RDL
Sbjct: 4837 LALQRDL 4843
>XP_005257602
          Length = 5256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LALRRDL 8
            LAL+RDL
Sbjct: 4837 LALQRDL 4843
>XP_005254929
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LALRRDLQ 9
           L LRRDL+
Sbjct: 94  LQLRRDLR 101
>XP_006718884
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LALRRD 7
          LALRRD
Sbjct: 45 LALRRD 50
>XP_006718882
          Length = 182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LALRRD 7
          LALRRD
Sbjct: 45 LALRRD 50
>XP_006718879
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  LALRRD 7
          LALRRD
Sbjct: 45 LALRRD 50
>XP_006717146
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 144 ALRRDL 149
>XP_005266132
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 144 ALRRDL 149
>XP_006717095
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELALRRDL 8
           ++ALR+DL
Sbjct: 698 KIALRKDL 705
>XP_006717094
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELALRRDL 8
           ++ALR+DL
Sbjct: 867 KIALRKDL 874
>XP_005251923
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELALRRDL 8
           ++ALR+DL
Sbjct: 867 KIALRKDL 874
>XP_005262783
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ALRRDL 8
           ALRRDL
Sbjct: 680 ALRRDL 685
>XP_005264316
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ELALRRDL 8
           ELAL +DL
Sbjct: 608 ELALEQDL 615
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.143    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 448,128
Number of extensions: 719
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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