Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              19     665
NP_660337                                                              17    2528
XP_006720926                                                           17    2528
XP_006720925                                                           17    2528
XP_006720924                                                           17    2528
XP_006720923                                                           17    2528
XP_005255218                                                           17    2528
XP_005255217                                                           17    2528
NP_001182155                                                           16    5631
NP_001229808                                                           16    5631
NP_001229807                                                           16    5631
NP_001229805                                                           16    5631
NP_001274170                                                           16    5631
NP_113637                                                              16    5631
NP_001012534                                                           16    5631
NP_001012532                                                           16    5631
NP_057686                                                              16    5631
NP_112188                                                              16    5631
NP_057419                                                              16    5631
NP_064501                                                              16    5631
NP_001121899                                                           16    5631
NP_001121900                                                           16    5631
NP_001229806                                                           16    5631
NP_001229804                                                           16    5631
NP_060725                                                              16    5631
XP_006724999                                                           16    5631
XP_006724998                                                           16    5631
XP_005249931                                                           16    5631
XP_005249930                                                           16    5631
XP_005249929                                                           16    5631
XP_005249928                                                           16    5631
XP_005249927                                                           16    5631
XP_005249926                                                           16    5631
XP_005249925                                                           16    5631
XP_006715850                                                           16    5631
XP_005249924                                                           16    5631
XP_005249923                                                           16    5631
NP_777589                                                              16    5631
NP_872325                                                              16    7355
NP_001157887                                                           16    7355
NP_057237                                                              16    7355
NP_005928                                                              16    7355
XP_006725391                                                           16    7355
XP_006725390                                                           16    7355
XP_006725387                                                           16    7355
XP_005257438                                                           16    7355
XP_005257437                                                           16    7355
XP_005257436                                                           16    7355
XP_005256892                                                           16    7355
XP_005256891                                                           16    7355
XP_005256890                                                           16    7355
NP_001265354                                                           15    9605
NP_001138363                                                           15    9605
NP_057670                                                              15    9605
NP_001265352                                                           15    9605
NP_037460                                                              15    9605
NP_443124                                                              15    9605
NP_775834                                                              15    9605
XP_005267813                                                           15    9605
XP_005267812                                                           15    9605
XP_005267811                                                           15    9605
XP_006715090                                                           15    9605
XP_006715089                                                           15    9605
XP_006715088                                                           15    9605
XP_005249008                                                           15    9605
NP_001070248                                                           15    9605
>NP_005350
          Length = 552

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           ELAFQP IS
Sbjct: 307 ELAFQPPIS 315
>NP_660337
          Length = 1748

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_006720926
          Length = 1383

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_006720925
          Length = 1674

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_006720924
          Length = 1679

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_006720923
          Length = 1738

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_005255218
          Length = 1750

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>XP_005255217
          Length = 1751

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +L F+PAIS
Sbjct: 181 DLCFEPAIS 189
>NP_001182155
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPAIS
Sbjct: 278 FQPAIS 283
>NP_001229808
          Length = 756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 464 QVAFQPSI 471
>NP_001229807
          Length = 756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 464 QVAFQPSI 471
>NP_001229805
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 529 QVAFQPSI 536
>NP_001274170
          Length = 267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ELAFQPAIS 9
          +++FQPA++
Sbjct: 3  KISFQPAVA 11
>NP_113637
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 858 ELAFSPA 864
>NP_001012534
          Length = 230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ELAFQPAIS 9
          +++FQPA++
Sbjct: 3  KISFQPAVA 11
>NP_001012532
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ELAFQPAIS 9
          +++FQPA++
Sbjct: 3  KISFQPAVA 11
>NP_057686
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  AFQPAIS 9
          AFQP++S
Sbjct: 42 AFQPSVS 48
>NP_112188
          Length = 267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  ELAFQPAIS 9
          +++FQPA++
Sbjct: 3  KISFQPAVA 11
>NP_057419
          Length = 600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPAIS
Sbjct: 386 FQPAIS 391
>NP_064501
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +LAFQP+ +
Sbjct: 741 DLAFQPSFT 749
>NP_001121899
          Length = 846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +LAFQP+ +
Sbjct: 740 DLAFQPSFT 748
>NP_001121900
          Length = 837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +LAFQP+ +
Sbjct: 731 DLAFQPSFT 739
>NP_001229806
          Length = 800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 508 QVAFQPSI 515
>NP_001229804
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 599 QVAFQPSI 606
>NP_060725
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ELAFQPAI 8
           ++AFQP+I
Sbjct: 534 QVAFQPSI 541
>XP_006724999
          Length = 409

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPAIS
Sbjct: 195 FQPAIS 200
>XP_006724998
          Length = 600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPAIS
Sbjct: 386 FQPAIS 391
>XP_005249931
          Length = 862

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 800 ELAFSPA 806
>XP_005249930
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 826 ELAFSPA 832
>XP_005249929
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 832 ELAFSPA 838
>XP_005249928
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 835 ELAFSPA 841
>XP_005249927
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 841 ELAFSPA 847
>XP_005249926
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 858 ELAFSPA 864
>XP_005249925
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_006715850
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_005249924
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 867 ELAFSPA 873
>XP_005249923
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 867 ELAFSPA 873
>NP_777589
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ELAFQPA 7
           ELAF PA
Sbjct: 832 ELAFSPA 838
>NP_872325
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           +LAF PA++
Sbjct: 573 DLAFMPAMN 581
>NP_001157887
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ELAFQP 6
          E+AFQP
Sbjct: 65 EIAFQP 70
>NP_057237
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ELAFQP 6
          E+AFQP
Sbjct: 65 EIAFQP 70
>NP_005928
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 342 FQPAVS 347
>XP_006725391
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 369 FQPAVS 374
>XP_006725390
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 253 FQPAVS 258
>XP_006725387
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 369 FQPAVS 374
>XP_005257438
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 369 FQPAVS 374
>XP_005257437
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 253 FQPAVS 258
>XP_005257436
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FQPAIS 9
           FQPA+S
Sbjct: 369 FQPAVS 374
>XP_005256892
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LAFQPAIS 9
          L FQPA++
Sbjct: 18 LGFQPALA 25
>XP_005256891
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LAFQPAIS 9
          L FQPA++
Sbjct: 18 LGFQPALA 25
>XP_005256890
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LAFQPAIS 9
          L FQPA++
Sbjct: 18 LGFQPALA 25
>NP_001265354
          Length = 1774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           ++AFQ A+S
Sbjct: 186 DVAFQAAVS 194
>NP_001138363
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AFQPAI 8
          AFQPA+
Sbjct: 65 AFQPAL 70
>NP_057670
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AFQPAI 8
          AFQPA+
Sbjct: 65 AFQPAL 70
>NP_001265352
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           ++AFQ A+S
Sbjct: 186 DVAFQAAVS 194
>NP_037460
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LAFQPA 7
           +AFQPA
Sbjct: 109 MAFQPA 114
>NP_443124
          Length = 2459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           ++AFQ A+S
Sbjct: 871 DVAFQAAVS 879
>NP_775834
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELAFQPAI 8
           EL+F+P I
Sbjct: 413 ELSFKPTI 420
>XP_005267813
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AFQPAI 8
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_005267812
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AFQPAI 8
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_005267811
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  AFQPAI 8
          AFQPA+
Sbjct: 65 AFQPAL 70
>XP_006715090
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELAFQPAI 8
           EL+F+P I
Sbjct: 257 ELSFKPTI 264
>XP_006715089
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELAFQPAI 8
           EL+F+P I
Sbjct: 350 ELSFKPTI 357
>XP_006715088
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELAFQPAI 8
           EL+F+P I
Sbjct: 350 ELSFKPTI 357
>XP_005249008
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ELAFQPAI 8
           EL+F+P I
Sbjct: 404 ELSFKPTI 411
>NP_001070248
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ELAFQPAIS 9
           ++AFQ A+S
Sbjct: 871 DVAFQAAVS 879
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.131    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 573,113
Number of extensions: 557
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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