Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721991                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_055685                                                              16    5631
NP_001077090                                                           16    5631
NP_060626                                                              16    7355
NP_056193                                                              16    7355
NP_004870                                                              16    7355
NP_001277064                                                           16    7355
NP_004332                                                              16    7355
NP_061841                                                              16    7355
NP_078942                                                              16    7355
XP_006720746                                                           16    7355
XP_005254721                                                           16    7355
XP_005265204                                                           16    7355
XP_006713221                                                           16    7355
XP_006713220                                                           16    7355
XP_006713219                                                           16    7355
XP_006713218                                                           16    7355
XP_006713217                                                           16    7355
XP_005265196                                                           16    7355
XP_005265195                                                           16    7355
XP_006713216                                                           16    7355
XP_006713215                                                           16    7355
XP_006713214                                                           16    7355
XP_006713213                                                           16    7355
XP_005265192                                                           16    7355
XP_005265191                                                           16    7355
XP_005265190                                                           16    7355
XP_006713212                                                           16    7355
XP_006713211                                                           16    7355
XP_006713210                                                           16    7355
XP_006713209                                                           16    7355
XP_006713208                                                           16    7355
XP_006713207                                                           16    7355
XP_006713206                                                           16    7355
XP_006713205                                                           16    7355
XP_006713204                                                           16    7355
XP_006713203                                                           16    7355
XP_005264615                                                           16    7355
XP_006712164                                                           16    7355
XP_005264614                                                           16    7355
XP_005264613                                                           16    7355
XP_005264612                                                           16    7355
XP_006711953                                                           16    7355
XP_006711952                                                           16    7355
XP_006711951                                                           16    7355
NP_848695                                                              15    9605
NP_848696                                                              15    9605
NP_835465                                                              15    9605
NP_001361                                                              15    9605
XP_006721895                                                           15    9605
XP_006712019                                                           15    9605
>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1266 ELADSMQT 1273
>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1266 ELADSMQT 1273
>XP_006721991
          Length = 1632

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1266 ELADSMQT 1273
>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1263 ELADSMQT 1270
>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1266 ELADSMQT 1273
>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ELADSMQT 8
            ELADSMQT
Sbjct: 1276 ELADSMQT 1283
>NP_055685
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LADSMQTF 9
           LADS+Q F
Sbjct: 96  LADSLQMF 103
>NP_001077090
          Length = 1239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LADSMQTF 9
           LADS+Q F
Sbjct: 96  LADSLQMF 103
>NP_060626
          Length = 4363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LADSMQTF 9
            L D+MQT+
Sbjct: 1005 LVDTMQTY 1012
>NP_056193
          Length = 4388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LADSMQTF 9
            L D+MQT+
Sbjct: 1005 LVDTMQTY 1012
>NP_004870
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LADSMQTF 9
         +ADS++TF
Sbjct: 1 MADSVKTF 8
>NP_001277064
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2 LADSMQTF 9
         +ADS++TF
Sbjct: 1 MADSVKTF 8
>NP_004332
          Length = 2225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 2007 LADSVQT 2013
>NP_061841
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ADSMQTF 9
           ADS QTF
Sbjct: 310 ADSSQTF 316
>NP_078942
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ELADSMQTF 9
          E+A+S+Q F
Sbjct: 72 EIAESVQAF 80
>XP_006720746
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ELADSMQTF 9
          E+A+S+Q F
Sbjct: 72 EIAESVQAF 80
>XP_005254721
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ELADSMQTF 9
          E+A+S+Q F
Sbjct: 72 EIAESVQAF 80
>XP_005265204
          Length = 2256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1491 ELADSMK 1497
>XP_006713221
          Length = 2268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713220
          Length = 2274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1509 ELADSMK 1515
>XP_006713219
          Length = 2280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713218
          Length = 2282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1517 ELADSMK 1523
>XP_006713217
          Length = 2283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_005265196
          Length = 2297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1532 ELADSMK 1538
>XP_005265195
          Length = 2297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1532 ELADSMK 1538
>XP_006713216
          Length = 2300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1535 ELADSMK 1541
>XP_006713215
          Length = 2309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1544 ELADSMK 1550
>XP_006713214
          Length = 2311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1546 ELADSMK 1552
>XP_006713213
          Length = 2314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_005265192
          Length = 2314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1549 ELADSMK 1555
>XP_005265191
          Length = 2314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1549 ELADSMK 1555
>XP_005265190
          Length = 2314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1549 ELADSMK 1555
>XP_006713212
          Length = 2320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713211
          Length = 2323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1558 ELADSMK 1564
>XP_006713210
          Length = 2326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1561 ELADSMK 1567
>XP_006713209
          Length = 2326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1561 ELADSMK 1567
>XP_006713208
          Length = 2335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713207
          Length = 2335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1570 ELADSMK 1576
>XP_006713206
          Length = 2337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713205
          Length = 2340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1575 ELADSMK 1581
>XP_006713204
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_006713203
          Length = 2352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ELADSMQ 7
            ELADSM+
Sbjct: 1587 ELADSMK 1593
>XP_005264615
          Length = 2162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 1944 LADSVQT 1950
>XP_006712164
          Length = 2179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 1961 LADSVQT 1967
>XP_005264614
          Length = 2191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 1973 LADSVQT 1979
>XP_005264613
          Length = 2208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 1990 LADSVQT 1996
>XP_005264612
          Length = 2242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LADSMQT 8
            LADS+QT
Sbjct: 2024 LADSVQT 2030
>XP_006711953
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  ADSMQTF 9
          ADS QTF
Sbjct: 85 ADSSQTF 91
>XP_006711952
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ADSMQTF 9
           ADS QTF
Sbjct: 224 ADSSQTF 230
>XP_006711951
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ADSMQTF 9
           ADS QTF
Sbjct: 251 ADSSQTF 257
>NP_848695
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LADSMQ 7
           LADSMQ
Sbjct: 372 LADSMQ 377
>NP_848696
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LADSMQ 7
           LADSMQ
Sbjct: 372 LADSMQ 377
>NP_835465
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DSMQTF 9
           D+MQTF
Sbjct: 226 DNMQTF 231
>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LADSMQTF 9
            +ADS+Q F
Sbjct: 3793 MADSLQEF 3800
>XP_006721895
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DSMQTF 9
           D+MQTF
Sbjct: 226 DNMQTF 231
>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LADSMQTF 9
            +ADS+Q F
Sbjct: 3793 MADSLQEF 3800
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.122    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 352,204
Number of extensions: 553
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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