Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_001138828                                                           16    5631
NP_001138827                                                           16    5631
NP_001078926                                                           16    5631
NP_001020087                                                           16    5631
NP_060961                                                              16    5631
NP_958861                                                              16    5631
NP_001273765                                                           16    5631
XP_005277698                                                           16    5631
XP_006717179                                                           16    5631
XP_005277697                                                           16    5631
XP_005277696                                                           16    5631
XP_005252048                                                           16    5631
XP_005277694                                                           16    5631
XP_006716978                                                           16    5631
XP_005272812                                                           16    5631
XP_005272811                                                           16    5631
XP_006716977                                                           16    5631
XP_005272808                                                           16    5631
XP_005272807                                                           16    5631
XP_005272806                                                           16    5631
XP_005272805                                                           16    5631
XP_005251574                                                           16    5631
XP_005251573                                                           16    5631
XP_005251572                                                           16    5631
XP_005251571                                                           16    5631
XP_005251570                                                           16    5631
XP_005263663                                                           16    5631
XP_005263662                                                           16    5631
XP_005263661                                                           16    5631
XP_005263660                                                           16    5631
XP_005263659                                                           16    5631
XP_005263657                                                           16    5631
NP_742000                                                              16    5631
NP_490597                                                              16    7355
NP_055114                                                              16    7355
NP_005568                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EKSTAVSQQ 9
           EKST VSQQ
Sbjct: 238 EKSTTVSQQ 246
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EKSTAVSQQ 9
          EKST VSQQ
Sbjct: 33 EKSTTVSQQ 41
>NP_001138828
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_001138827
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 49 EKSLAVSQ 56
>NP_001078926
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_001020087
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_060961
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_958861
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_001273765
          Length = 113

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005277698
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_006717179
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005277697
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005277696
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005252048
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005277694
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_006716978
          Length = 210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272812
          Length = 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272811
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_006716977
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272808
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272807
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272806
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005272805
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005251574
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005251573
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 49 EKSLAVSQ 56
>XP_005251572
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005251571
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005251570
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005263663
          Length = 241

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005263662
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 49 EKSLAVSQ 56
>XP_005263661
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005263660
          Length = 359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 49 EKSLAVSQ 56
>XP_005263659
          Length = 366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>XP_005263657
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_742000
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  EKSTAVSQ 8
          EKS AVSQ
Sbjct: 85 EKSLAVSQ 92
>NP_490597
          Length = 1362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKSTAVSQQ 9
           EKS+ VS+Q
Sbjct: 345 EKSSKVSEQ 353
>NP_055114
          Length = 722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EKSTAVSQQ 9
           EKS+ VS+Q
Sbjct: 345 EKSSKVSEQ 353
>NP_005568
          Length = 2040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    STAVSQQ 9
            STAVS+Q
Sbjct: 1256 STAVSEQ 1262
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.275   0.0883    0.182 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 261,723
Number of extensions: 374
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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