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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001189394                                                           18    1935
NP_001189393                                                           18    1935
NP_006615                                                              18    1935
NP_001189395                                                           18    1935
NP_001189396                                                           18    1935
NP_997644                                                              18    1935
NP_001189397                                                           18    1935
XP_005252420                                                           18    1935
XP_006717439                                                           18    1935
XP_005252419                                                           18    1935
XP_005252418                                                           18    1935
XP_005252417                                                           18    1935
XP_005252416                                                           18    1935
NP_008949                                                              17    3301
XP_006717006                                                           17    3301
XP_006717005                                                           17    3301
XP_006717004                                                           17    3301
XP_006717003                                                           17    3301
XP_005251736                                                           17    3301
NP_002206                                                              16    7355
NP_002363                                                              16    7355
NP_001107                                                              15    9605
NP_001035519                                                           15    9605
NP_065904                                                              15    9605
XP_005255136                                                           15    9605
XP_005266415                                                           15    9605
XP_005266414                                                           15    9605
XP_005253507                                                           15    9605

>NP_001189394
          Length = 517

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 423 EKRQAVN 429



>NP_001189393
          Length = 548

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 454 EKRQAVN 460



>NP_006615
          Length = 602

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 508 EKRQAVN 514



>NP_001189395
          Length = 547

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 453 EKRQAVN 459



>NP_001189396
          Length = 514

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 454 EKRQAVN 460



>NP_997644
          Length = 567

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 507 EKRQAVN 513



>NP_001189397
          Length = 568

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 508 EKRQAVN 514



>XP_005252420
          Length = 547

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 453 EKRQAVN 459



>XP_006717439
          Length = 548

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 454 EKRQAVN 460



>XP_005252419
          Length = 548

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 454 EKRQAVN 460



>XP_005252418
          Length = 548

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 454 EKRQAVN 460



>XP_005252417
          Length = 601

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 507 EKRQAVN 513



>XP_005252416
          Length = 602

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   EKRQAVN 7
           EKRQAVN
Sbjct: 508 EKRQAVN 514



>NP_008949
          Length = 2325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1861 EKREAVNSL 1869



>XP_006717006
          Length = 1760

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1281 EKREAVNSL 1289



>XP_006717005
          Length = 1788

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1309 EKREAVNSL 1317



>XP_006717004
          Length = 2240

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1861 EKREAVNSL 1869



>XP_006717003
          Length = 2278

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1861 EKREAVNSL 1869



>XP_005251736
          Length = 2325

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EKRQAVNMM 9
            EKR+AVN +
Sbjct: 1861 EKREAVNSL 1869



>NP_002206
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EKRQAVN 7
          EKRQAV+
Sbjct: 39 EKRQAVD 45



>NP_002363
          Length = 1144

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKRQAVN 7
           EKR AVN
Sbjct: 985 EKRSAVN 991



>NP_001107
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EKRQAVNM 8
           EK++ VNM
Sbjct: 479 EKKEMVNM 486



>NP_001035519
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EKRQAVNMM 9
           E+R A+N+M
Sbjct: 775 EERNAMNVM 783



>NP_065904
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EKRQAVNM 8
           EKR+++N+
Sbjct: 366 EKRRSINL 373



>XP_005255136
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EKRQAVNM 8
           EK++ VNM
Sbjct: 479 EKKEMVNM 486



>XP_005266415
          Length = 1158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EKRQAVNMM 9
           E+R A+N+M
Sbjct: 775 EERNAMNVM 783



>XP_005266414
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EKRQAVNMM 9
           E+R A+N+M
Sbjct: 775 EERNAMNVM 783



>XP_005253507
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EKRQAVNM 8
           EKR+++N+
Sbjct: 366 EKRRSINL 373



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.117    0.284 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 370,391
Number of extensions: 305
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)