Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     299
XP_005262424                                                           20     299
NP_055907                                                              18    1135
XP_005255242                                                           18    1135
XP_005255241                                                           18    1135
XP_005255240                                                           18    1135
XP_005255239                                                           18    1135
NP_789787                                                              17    3301
NP_001193784                                                           17    4312
NP_001243398                                                           17    4312
NP_036462                                                              17    4312
NP_001243397                                                           17    4312
NP_003218                                                              17    4312
XP_005269721                                                           17    4312
XP_005250611                                                           17    4312
XP_006716166                                                           17    4312
XP_005250610                                                           17    4312
NP_071351                                                              16    5631
NP_001274420                                                           16    5631
NP_079414                                                              16    5631
NP_001248385                                                           16    5631
NP_002339                                                              16    5631
NP_001248386                                                           16    5631
XP_005266602                                                           16    5631
XP_006712026                                                           16    5631
XP_005264244                                                           16    5631
XP_006711388                                                           16    5631
XP_006711387                                                           16    5631
XP_006711386                                                           16    5631
XP_006711385                                                           16    5631
XP_006711384                                                           16    5631
XP_006711383                                                           16    5631
XP_005245221                                                           16    5631
NP_055935                                                              16    7355
NP_055625                                                              16    7355
NP_001171671                                                           16    7355
NP_006768                                                              16    7355
XP_006711734                                                           16    7355
XP_006711733                                                           16    7355
XP_006711732                                                           16    7355
XP_006711731                                                           16    7355
XP_006711730                                                           16    7355
XP_006711729                                                           16    7355
XP_005245695                                                           16    7355
NP_001013375                                                           16    7355
NP_079085                                                              15    9605
NP_001137322                                                           15    9605
NP_005849                                                              15    9605
NP_001073908                                                           15    9605
NP_005115                                                              15    9605
NP_001265138                                                           15    9605
NP_001265139                                                           15    9605
NP_001138548                                                           15    9605
NP_061936                                                              15    9605
NP_054872                                                              15    9605
NP_055127                                                              15    9605
NP_060745                                                              15    9605
XP_005259763                                                           15    9605
XP_005255329                                                           15    9605
XP_006720940                                                           15    9605
XP_005255327                                                           15    9605
XP_006719668                                                           15    9605
XP_006715354                                                           15    9605
XP_005249564                                                           15    9605
XP_006715353                                                           15    9605
XP_006712055                                                           15    9605
XP_006712054                                                           15    9605
XP_005264324                                                           15    9605
>NP_722576
          Length = 3080

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EKLSTPLNN 9
           EKLSTPL+N
Sbjct: 891 EKLSTPLDN 899
>XP_005262424
          Length = 2875

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EKLSTPLNN 9
           EKLSTPL+N
Sbjct: 686 EKLSTPLDN 694
>NP_055907
          Length = 3661

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EKL TPLN
Sbjct: 2053 EKLKTPLN 2060
>XP_005255242
          Length = 3609

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EKL TPLN
Sbjct: 2001 EKLKTPLN 2008
>XP_005255241
          Length = 3637

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EKL TPLN
Sbjct: 2001 EKLKTPLN 2008
>XP_005255240
          Length = 3663

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EKL TPLN
Sbjct: 2027 EKLKTPLN 2034
>XP_005255239
          Length = 3689

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EKL TPLN
Sbjct: 2053 EKLKTPLN 2060
>NP_789787
          Length = 333

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EKLSTPLNN 9
          +KLS PLN+
Sbjct: 82 QKLSEPLNH 90
>NP_001193784
          Length = 630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLSTPLNN 9
           + STP+NN
Sbjct: 234 RTSTPINN 241
>NP_001243398
          Length = 1781

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSTPLNN 9
            LSTPL+N
Sbjct: 1557 LSTPLSN 1563
>NP_036462
          Length = 2073

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSTPLNN 9
            LSTPL+N
Sbjct: 1849 LSTPLSN 1855
>NP_001243397
          Length = 1890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSTPLNN 9
            LSTPL+N
Sbjct: 1666 LSTPLSN 1672
>NP_003218
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLSTPLNN 9
           + STP+NN
Sbjct: 405 RTSTPINN 412
>XP_005269721
          Length = 2073

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LSTPLNN 9
            LSTPL+N
Sbjct: 1849 LSTPLSN 1855
>XP_005250611
          Length = 763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLSTPLNN 9
           + STP+NN
Sbjct: 405 RTSTPINN 412
>XP_006716166
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLSTPLNN 9
           + STP+NN
Sbjct: 405 RTSTPINN 412
>XP_005250610
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLSTPLNN 9
           + STP+NN
Sbjct: 405 RTSTPINN 412
>NP_071351
          Length = 2752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EKLSTPLNN 9
            +KLS PL N
Sbjct: 2551 DKLSFPLKN 2559
>NP_001274420
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EKLSTP 6
            EKLSTP
Sbjct: 1179 EKLSTP 1184
>NP_079414
          Length = 944

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LSTPLN 8
           LSTPLN
Sbjct: 666 LSTPLN 671
>NP_001248385
          Length = 641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 502 EKLDTPL 508
>NP_002339
          Length = 655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 516 EKLDTPL 522
>NP_001248386
          Length = 565

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 426 EKLDTPL 432
>XP_005266602
          Length = 922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LSTPLN 8
           LSTPLN
Sbjct: 644 LSTPLN 649
>XP_006712026
          Length = 937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EKLSTP 6
           EKLSTP
Sbjct: 321 EKLSTP 326
>XP_005264244
          Length = 1795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EKLSTP 6
            EKLSTP
Sbjct: 1179 EKLSTP 1184
>XP_006711388
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 412 EKLDTPL 418
>XP_006711387
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 412 EKLDTPL 418
>XP_006711386
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 426 EKLDTPL 432
>XP_006711385
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 502 EKLDTPL 508
>XP_006711384
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 516 EKLDTPL 522
>XP_006711383
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 502 EKLDTPL 508
>XP_005245221
          Length = 664

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EKLSTPL 7
           EKL TPL
Sbjct: 516 EKLDTPL 522
>NP_055935
          Length = 4169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    EKLSTPLN 8
            EK+ TPL+
Sbjct: 3184 EKMKTPLS 3191
>NP_055625
          Length = 3117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2713 EKLCTPL 2719
>NP_001171671
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EKLSTPLN 8
           +KL TP+N
Sbjct: 247 QKLPTPVN 254
>NP_006768
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EKLSTPLN 8
           +KL TP+N
Sbjct: 247 QKLPTPVN 254
>XP_006711734
          Length = 3136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2732 EKLCTPL 2738
>XP_006711733
          Length = 3137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2733 EKLCTPL 2739
>XP_006711732
          Length = 3154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2750 EKLCTPL 2756
>XP_006711731
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2753 EKLCTPL 2759
>XP_006711730
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2753 EKLCTPL 2759
>XP_006711729
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2754 EKLCTPL 2760
>XP_005245695
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    EKLSTPL 7
            EKL TPL
Sbjct: 2754 EKLCTPL 2760
>NP_001013375
          Length = 309

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EKLSTPL 7
          EKL+TP+
Sbjct: 53 EKLNTPM 59
>NP_079085
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 368 TPLNN 372
>NP_001137322
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 367 TPLNN 371
>NP_005849
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           E LSTP N
Sbjct: 218 EPLSTPWN 225
>NP_001073908
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LSTPLN 8
          LSTP+N
Sbjct: 5  LSTPIN 10
>NP_005115
          Length = 1475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>NP_001265138
          Length = 1506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>NP_001265139
          Length = 1433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>NP_001138548
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           EKLS P N
Sbjct: 808 EKLSLPQN 815
>NP_061936
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           EKLS P N
Sbjct: 866 EKLSLPQN 873
>NP_054872
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 380 TPLNN 384
>NP_055127
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  EKLSTPL 7
          E LSTPL
Sbjct: 31 EPLSTPL 37
>NP_060745
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 436 TPLNN 440
>XP_005259763
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           E LSTP N
Sbjct: 205 EPLSTPWN 212
>XP_005255329
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 367 TPLNN 371
>XP_006720940
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 380 TPLNN 384
>XP_005255327
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 380 TPLNN 384
>XP_006719668
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   TPLNN 9
           TPLNN
Sbjct: 368 TPLNN 372
>XP_006715354
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>XP_005249564
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>XP_006715353
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EKLSTPL 7
           EK+S+PL
Sbjct: 316 EKMSSPL 322
>XP_006712055
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           EKLS P N
Sbjct: 798 EKLSLPQN 805
>XP_006712054
          Length = 934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           EKLS P N
Sbjct: 819 EKLSLPQN 826
>XP_005264324
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EKLSTPLN 8
           EKLS P N
Sbjct: 877 EKLSLPQN 884
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.293    0.117    0.306 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 782,413
Number of extensions: 1181
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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