Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006209                                                              20     390
XP_006713721                                                           20     390
NP_004251                                                              17    4312
NP_006258                                                              16    5631
NP_001157935                                                           16    5631
NP_001019628                                                           16    5631
NP_001116835                                                           16    5631
NP_005045                                                              16    5631
NP_060089                                                              16    5631
NP_872394                                                              16    5631
NP_001071638                                                           16    5631
NP_001137485                                                           16    5631
XP_006718546                                                           16    5631
XP_005263879                                                           16    5631
XP_005263878                                                           16    5631
XP_005263877                                                           16    5631
XP_005263876                                                           16    5631
XP_006712857                                                           16    5631
XP_005263813                                                           16    5631
XP_005263812                                                           16    5631
XP_005263810                                                           16    5631
XP_005263805                                                           16    5631
XP_005263804                                                           16    5631
XP_006712771                                                           16    5631
XP_005264064                                                           16    5631
XP_005264063                                                           16    5631
XP_005264062                                                           16    5631
XP_005264061                                                           16    5631
XP_005264060                                                           16    5631
XP_005264059                                                           16    5631
XP_006712517                                                           16    5631
XP_005264592                                                           16    5631
XP_005264371                                                           16    5631
XP_006712081                                                           16    5631
XP_005264370                                                           16    5631
XP_005264369                                                           16    5631
NP_055992                                                              16    5631
XP_006717377                                                           16    7355
XP_006717376                                                           16    7355
XP_005272289                                                           16    7355
XP_006717375                                                           16    7355
XP_005270453                                                           16    7355
XP_005270452                                                           16    7355
XP_005270451                                                           16    7355
NP_003925                                                              16    7355
NP_006836                                                              16    7355
NP_001138303                                                           15    9605
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_001231509                                                           15    9605
NP_003487                                                              15    9605
NP_001810                                                              15    9605
NP_001254629                                                           15    9605
NP_149079                                                              15    9605
NP_001257697                                                           15    9605
NP_659457                                                              15    9605
NP_003176                                                              15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_006722482                                                           15    9605
XP_006719430                                                           15    9605
XP_006719429                                                           15    9605
XP_006719428                                                           15    9605
XP_005253933                                                           15    9605
XP_006711057                                                           15    9605
NP_001084                                                              15    9605
>NP_006209
          Length = 1068

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EITAQEKDF 9
           EIT QEKDF
Sbjct: 542 EITEQEKDF 550
>XP_006713721
          Length = 1068

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EITAQEKDF 9
           EIT QEKDF
Sbjct: 542 EITEQEKDF 550
>NP_004251
          Length = 1208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    EITAQEKD 8
            ++TA+EKD
Sbjct: 1042 DLTAEEKD 1049
>NP_006258
          Length = 3224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2441 TAQEKD 2446
>NP_001157935
          Length = 1765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>NP_001019628
          Length = 1748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1450 TAQEKD 1455
>NP_001116835
          Length = 1765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>NP_005045
          Length = 1765

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>NP_060089
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  EITAQEKD 8
          E+TA+EK+
Sbjct: 37 ELTAEEKE 44
>NP_872394
          Length = 1758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1466 TAQEKD 1471
>NP_001071638
          Length = 1756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>NP_001137485
          Length = 1758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1466 TAQEKD 1471
>XP_006718546
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TAQEKD 8
           TAQEKD
Sbjct: 508 TAQEKD 513
>XP_005263879
          Length = 1480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1180 TAQEKD 1185
>XP_005263878
          Length = 1660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>XP_005263877
          Length = 1686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>XP_005263876
          Length = 1739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1439 TAQEKD 1444
>XP_006712857
          Length = 1748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1448 TAQEKD 1453
>XP_005263813
          Length = 1480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1180 TAQEKD 1185
>XP_005263812
          Length = 1660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>XP_005263810
          Length = 1739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1439 TAQEKD 1444
>XP_005263805
          Length = 1480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1180 TAQEKD 1185
>XP_005263804
          Length = 1660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>XP_006712771
          Length = 1766

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1466 TAQEKD 1471
>XP_005264064
          Length = 2282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1465 TAQEKD 1470
>XP_005264063
          Length = 3136

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2319 TAQEKD 2324
>XP_005264062
          Length = 3232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2415 TAQEKD 2420
>XP_005264061
          Length = 3232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2441 TAQEKD 2446
>XP_005264060
          Length = 3250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2441 TAQEKD 2446
>XP_005264059
          Length = 3258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 2441 TAQEKD 2446
>XP_006712517
          Length = 1757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1466 TAQEKD 1471
>XP_005264592
          Length = 1653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>XP_005264371
          Length = 1653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>XP_006712081
          Length = 1679

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>XP_005264370
          Length = 1756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>XP_005264369
          Length = 1756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    TAQEKD 8
            TAQEKD
Sbjct: 1458 TAQEKD 1463
>NP_055992
          Length = 619

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TAQEKD 8
           TAQEKD
Sbjct: 614 TAQEKD 619
>XP_006717377
          Length = 377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITAQEKD 8
           +TAQE+D
Sbjct: 127 LTAQERD 133
>XP_006717376
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITAQEKD 8
           +TAQE+D
Sbjct: 235 LTAQERD 241
>XP_005272289
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITAQEKD 8
           +TAQE+D
Sbjct: 322 LTAQERD 328
>XP_006717375
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITAQEKD 8
           +TAQE+D
Sbjct: 321 LTAQERD 327
>XP_005270453
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ITAQEKD 8
          ITAQE D
Sbjct: 68 ITAQEND 74
>XP_005270452
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ITAQEKD 8
           ITAQE D
Sbjct: 122 ITAQEND 128
>XP_005270451
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ITAQEKD 8
           ITAQE D
Sbjct: 113 ITAQEND 119
>NP_003925
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITAQEKD 8
           +TAQE+D
Sbjct: 322 LTAQERD 328
>NP_006836
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ITAQEKD 8
           ITAQE D
Sbjct: 122 ITAQEND 128
>NP_001138303
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EITAQEKDF 9
           E+T + KDF
Sbjct: 167 ELTERAKDF 175
>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EITAQEKD 8
            E TAQEK+
Sbjct: 1897 EETAQEKE 1904
>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EITAQEKD 8
            E TAQEK+
Sbjct: 1897 EETAQEKE 1904
>NP_001231509
          Length = 3859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    ITAQEKDF 9
            + AQEK F
Sbjct: 1231 VAAQEKSF 1238
>NP_003487
          Length = 3830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    ITAQEKDF 9
            + AQEK F
Sbjct: 1231 VAAQEKSF 1238
>NP_001810
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EITAQEKDF 9
           E+T  EK+F
Sbjct: 554 ELTLNEKNF 562
>NP_001254629
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EITAQEKDF 9
           E+T + KDF
Sbjct: 167 ELTERAKDF 175
>NP_149079
          Length = 837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EITAQEK 7
           E+TA+EK
Sbjct: 134 EVTAREK 140
>NP_001257697
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EITAQEK 7
          E+TA+EK
Sbjct: 39 EVTAREK 45
>NP_659457
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EITAQEKDF 9
           E  AQEK+F
Sbjct: 352 EEKAQEKEF 360
>NP_003176
          Length = 1085

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TAQEKDF 9
           TAQ+K+F
Sbjct: 920 TAQQKNF 926
>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EITAQEKD 8
            E TAQEK+
Sbjct: 1897 EETAQEKE 1904
>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EITAQEKD 8
            E TAQEK+
Sbjct: 1896 EETAQEKE 1903
>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EITAQEKD 8
            E TAQEK+
Sbjct: 1897 EETAQEKE 1904
>XP_006722482
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EITAQEKDF 9
           E  AQEK+F
Sbjct: 153 EEKAQEKEF 161
>XP_006719430
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ITAQEKDF 9
            + AQEK+F
Sbjct: 1262 LIAQEKEF 1269
>XP_006719429
          Length = 2395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ITAQEKDF 9
            + AQEK+F
Sbjct: 1401 LIAQEKEF 1408
>XP_006719428
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ITAQEKDF 9
            + AQEK+F
Sbjct: 1464 LIAQEKEF 1471
>XP_005253933
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ITAQEKDF 9
            + AQEK+F
Sbjct: 1464 LIAQEKEF 1471
>XP_006711057
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EITAQEK 7
           E+TA+EK
Sbjct: 135 EVTAREK 141
>NP_001084
          Length = 2458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ITAQEKDF 9
            + AQEK+F
Sbjct: 1464 LIAQEKEF 1471
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.125    0.316 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 623,149
Number of extensions: 1026
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package