Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     665
NP_055085                                                              19     665
NP_001229965                                                           19     665
NP_001119807                                                           19     665
XP_006723055                                                           19     665
XP_005258525                                                           19     665
XP_006718907                                                           19     665
XP_006718906                                                           19     665
XP_005271619                                                           19     665
XP_005271618                                                           19     665
NP_001271226                                                           18    1482
NP_001271227                                                           18    1482
XP_005254507                                                           18    1482
XP_005254506                                                           18    1482
XP_005254505                                                           18    1482
XP_006720635                                                           18    1482
XP_006720634                                                           18    1482
NP_004564                                                              18    1482
NP_001271279                                                           18    1935
NP_001025190                                                           18    1935
NP_689995                                                              18    1935
NP_001153699                                                           17    3301
NP_079413                                                              17    3301
XP_006720764                                                           17    3301
XP_005254752                                                           17    3301
XP_006720763                                                           17    3301
XP_006720762                                                           17    3301
XP_005254751                                                           17    3301
NP_689823                                                              16    5631
NP_055661                                                              16    7355
NP_060382                                                              16    7355
NP_002579                                                              16    7355
NP_115778                                                              16    7355
NP_001158608                                                           16    7355
XP_005251177                                                           16    7355
XP_005263140                                                           16    7355
XP_005264276                                                           16    7355
XP_005264275                                                           16    7355
NP_055962                                                              16    7355
NP_997192                                                              15    9605
NP_055872                                                              15    9605
NP_620168                                                              15    9605
NP_001171473                                                           15    9605
XP_006722719                                                           15    9605
XP_006722718                                                           15    9605
XP_006722717                                                           15    9605
XP_006719852                                                           15    9605
XP_005266357                                                           15    9605
XP_006719851                                                           15    9605
XP_006719850                                                           15    9605
XP_006719849                                                           15    9605
XP_006719848                                                           15    9605
XP_005266356                                                           15    9605
XP_006719847                                                           15    9605
XP_006719846                                                           15    9605
XP_006719845                                                           15    9605
XP_006719844                                                           15    9605
XP_006719843                                                           15    9605
XP_006719842                                                           15    9605
XP_006717380                                                           15    9605
XP_006713366                                                           15    9605
NP_443192                                                              15    9605
>NP_000042
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EISSLVNYF 9
           EISSLV YF
Sbjct: 96  EISSLVKYF 104
>NP_055085
          Length = 487

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           +I+SLVNYF
Sbjct: 370 DINSLVNYF 378
>NP_001229965
          Length = 487

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           +I+SLVNYF
Sbjct: 370 DINSLVNYF 378
>NP_001119807
          Length = 487

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           +I+SLVNYF
Sbjct: 370 DINSLVNYF 378
>XP_006723055
          Length = 260

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           +I+SLVNYF
Sbjct: 143 DINSLVNYF 151
>XP_005258525
          Length = 278

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           +I+SLVNYF
Sbjct: 161 DINSLVNYF 169
>XP_006718907
          Length = 3050

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EISSLVNYF 9
           EISSLV YF
Sbjct: 96  EISSLVKYF 104
>XP_006718906
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EISSLVNYF 9
           EISSLV YF
Sbjct: 96  EISSLVKYF 104
>XP_005271619
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EISSLVNYF 9
           EISSLV YF
Sbjct: 96  EISSLVKYF 104
>XP_005271618
          Length = 3056

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EISSLVNYF 9
           EISSLV YF
Sbjct: 96  EISSLVKYF 104
>NP_001271226
          Length = 1181

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 541 EMSSLVNY 548
>NP_001271227
          Length = 1170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>XP_005254507
          Length = 1070

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>XP_005254506
          Length = 1123

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>XP_005254505
          Length = 1124

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>XP_006720635
          Length = 1125

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>XP_006720634
          Length = 1184

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>NP_004564
          Length = 1185

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+SSLVNY
Sbjct: 545 EMSSLVNY 552
>NP_001271279
          Length = 345

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+S+LVNY
Sbjct: 153 EVSNLVNY 160
>NP_001025190
          Length = 357

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+S+LVNY
Sbjct: 165 EVSNLVNY 172
>NP_689995
          Length = 357

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           E+S+LVNY
Sbjct: 165 EVSNLVNY 172
>NP_001153699
          Length = 2330

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>NP_079413
          Length = 2443

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>XP_006720764
          Length = 1584

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>XP_005254752
          Length = 2357

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1301 EVKSLIQYF 1309
>XP_006720763
          Length = 2395

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>XP_006720762
          Length = 2397

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>XP_005254751
          Length = 2407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            E+ SL+ YF
Sbjct: 1387 EVKSLIQYF 1395
>NP_689823
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ISSLVNY 8
           +SSL+NY
Sbjct: 424 LSSLINY 430
>NP_055661
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EISSLVNY 8
           E+S ++NY
Sbjct: 773 EVSRIINY 780
>NP_060382
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           E+S+L+N++
Sbjct: 588 ELSNLLNFY 596
>NP_002579
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSLVNYF 9
           SSL NYF
Sbjct: 401 SSLKNYF 407
>NP_115778
          Length = 863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SSLVNYF 9
           SSL NYF
Sbjct: 401 SSLKNYF 407
>NP_001158608
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           E+S+L+N++
Sbjct: 588 ELSNLLNFY 596
>XP_005251177
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   EISSLVNY 8
           E+S ++NY
Sbjct: 625 EVSRIINY 632
>XP_005263140
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EISSLVNYF 9
           E+S+L+N++
Sbjct: 600 ELSNLLNFY 608
>XP_005264276
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>XP_005264275
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>NP_055962
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EISSLVNY 8
           ++SSLV+Y
Sbjct: 491 QVSSLVSY 498
>NP_997192
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EISSLVNY 8
           EIS LV+Y
Sbjct: 467 EISPLVSY 474
>NP_055872
          Length = 4678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3092 EISSALNMF 3100
>NP_620168
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSLVNYF 9
            +SLVN+F
Sbjct: 1089 TSLVNFF 1095
>NP_001171473
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSLVNYF 9
            +SLVN+F
Sbjct: 1052 TSLVNFF 1058
>XP_006722719
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSLVNYF 9
            +SLVN+F
Sbjct: 1013 TSLVNFF 1019
>XP_006722718
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSLVNYF 9
            +SLVN+F
Sbjct: 1099 TSLVNFF 1105
>XP_006722717
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    SSLVNYF 9
            +SLVN+F
Sbjct: 1099 TSLVNFF 1105
>XP_006719852
          Length = 4752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3169 EISSALNMF 3177
>XP_005266357
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3017 EISSALNMF 3025
>XP_006719851
          Length = 4689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3103 EISSALNMF 3111
>XP_006719850
          Length = 4697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3111 EISSALNMF 3119
>XP_006719849
          Length = 4703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3117 EISSALNMF 3125
>XP_006719848
          Length = 4737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3151 EISSALNMF 3159
>XP_005266356
          Length = 4755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3169 EISSALNMF 3177
>XP_006719847
          Length = 4761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3175 EISSALNMF 3183
>XP_006719846
          Length = 4763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3177 EISSALNMF 3185
>XP_006719845
          Length = 4772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3186 EISSALNMF 3194
>XP_006719844
          Length = 4789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3203 EISSALNMF 3211
>XP_006719843
          Length = 4794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3211 EISSALNMF 3219
>XP_006719842
          Length = 4797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EISSLVNYF 9
            EISS +N F
Sbjct: 3211 EISSALNMF 3219
>XP_006717380
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EISSLVNY 8
           EIS LV+Y
Sbjct: 467 EISPLVSY 474
>XP_006713366
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EISSLVNY 8
           E+S L+NY
Sbjct: 469 ELSCLLNY 476
>NP_443192
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  SSLVNYF 9
          SSL NYF
Sbjct: 56 SSLRNYF 62
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.137    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 411,701
Number of extensions: 720
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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