Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     509
NP_671714                                                              20     509
XP_006715890                                                           20     509
XP_005250160                                                           20     509
XP_005250159                                                           20     509
NP_005104                                                              17    3301
NP_001268735                                                           17    4312
NP_001007123                                                           17    4312
NP_001268734                                                           17    4312
XP_005272487                                                           17    4312
XP_005272486                                                           17    4312
XP_005272483                                                           17    4312
XP_005272482                                                           17    4312
NP_004235                                                              16    5631
NP_981961                                                              16    5631
NP_056473                                                              16    5631
XP_005253586                                                           16    5631
XP_005253585                                                           16    5631
NP_001128715                                                           16    7355
NP_001128717                                                           16    7355
NP_001128716                                                           16    7355
NP_000347                                                              16    7355
NP_001182070                                                           16    7355
NP_001034                                                              16    7355
NP_001165972                                                           16    7355
NP_001165973                                                           16    7355
NP_443078                                                              16    7355
NP_001165975                                                           16    7355
XP_006726603                                                           16    7355
XP_006725215                                                           16    7355
XP_006721326                                                           16    7355
XP_006719237                                                           16    7355
XP_005268564                                                           16    7355
XP_005268563                                                           16    7355
XP_005268562                                                           16    7355
XP_005268561                                                           16    7355
XP_005268560                                                           16    7355
XP_005268559                                                           16    7355
XP_005276075                                                           16    7355
NP_001273598                                                           15    9605
NP_001273599                                                           15    9605
NP_001273601                                                           15    9605
NP_001273600                                                           15    9605
NP_861522                                                              15    9605
NP_001273597                                                           15    9605
NP_001107604                                                           15    9605
NP_060164                                                              15    9605
NP_387467                                                              15    9605
XP_006726609                                                           15    9605
XP_006719787                                                           15    9605
XP_005269291                                                           15    9605
XP_005251223                                                           15    9605
XP_005265784                                                           15    9605
XP_005265783                                                           15    9605
XP_005265781                                                           15    9605
XP_005265778                                                           15    9605
XP_005246845                                                           15    9605
XP_006712765                                                           15    9605
XP_006712764                                                           15    9605
XP_005246844                                                           15    9605
XP_006712763                                                           15    9605
XP_006712762                                                           15    9605
XP_006712761                                                           15    9605
XP_005246712                                                           15    9605
XP_005246711                                                           15    9605
XP_006710027                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           EI+QLMGTV
Sbjct: 393 EIKQLMGTV 401
>NP_671714
          Length = 3899

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           EI+QLMGTV
Sbjct: 393 EIKQLMGTV 401
>XP_006715890
          Length = 3860

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           EI+QLMGTV
Sbjct: 393 EIKQLMGTV 401
>XP_005250160
          Length = 3939

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           EI+QLMGTV
Sbjct: 393 EIKQLMGTV 401
>XP_005250159
          Length = 3952

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           EI+QLMGTV
Sbjct: 393 EIKQLMGTV 401
>NP_005104
          Length = 731

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           EIQ+LMG +
Sbjct: 481 EIQKLMGQI 489
>NP_001268735
          Length = 704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>NP_001007123
          Length = 749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>NP_001268734
          Length = 704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>XP_005272487
          Length = 609

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>XP_005272486
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>XP_005272483
          Length = 749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>XP_005272482
          Length = 749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   EIQQLMGTV 9
           +++QLMG++
Sbjct: 358 DVEQLMGSI 366
>NP_004235
          Length = 1156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           EIQ+L+G V
Sbjct: 389 EIQRLLGKV 397
>NP_981961
          Length = 1121

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           EIQ+L+G V
Sbjct: 389 EIQRLLGKV 397
>NP_056473
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           ++QQL+G V
Sbjct: 569 QVQQLLGKV 577
>XP_005253586
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           EIQ+L+G V
Sbjct: 389 EIQRLLGKV 397
>XP_005253585
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EIQQLMGTV 9
           EIQ+L+G V
Sbjct: 389 EIQRLLGKV 397
>NP_001128715
          Length = 1488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1420 ELQKGMGTV 1428
>NP_001128717
          Length = 1412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1344 ELQKGMGTV 1352
>NP_001128716
          Length = 1451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1383 ELQKGMGTV 1391
>NP_000347
          Length = 1411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1343 ELQKGMGTV 1351
>NP_001182070
          Length = 1450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1382 ELQKGMGTV 1390
>NP_001034
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           +IQQ+MG
Sbjct: 504 DIQQMMG 510
>NP_001165972
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           +IQQ+MG
Sbjct: 504 DIQQMMG 510
>NP_001165973
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           +IQQ+MG
Sbjct: 399 DIQQMMG 405
>NP_443078
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IQQLMGTV 9
           +QQL GTV
Sbjct: 558 LQQLNGTV 565
>NP_001165975
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           +IQQ+MG
Sbjct: 504 DIQQMMG 510
>XP_006726603
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IQQLMGTV 9
           I QL+GTV
Sbjct: 146 ITQLLGTV 153
>XP_006725215
          Length = 1264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IQQLMGTV 9
           I QL+GTV
Sbjct: 146 ITQLLGTV 153
>XP_006721326
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           +IQQ+MG
Sbjct: 504 DIQQMMG 510
>XP_006719237
          Length = 1263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IQQLMGTV 9
           I QL+GTV
Sbjct: 146 ITQLLGTV 153
>XP_005268564
          Length = 1449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1381 ELQKGMGTV 1389
>XP_005268563
          Length = 1488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1420 ELQKGMGTV 1428
>XP_005268562
          Length = 1489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1421 ELQKGMGTV 1429
>XP_005268561
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1457 ELQKGMGTV 1465
>XP_005268560
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1457 ELQKGMGTV 1465
>XP_005268559
          Length = 1526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EIQQLMGTV 9
            E+Q+ MGTV
Sbjct: 1458 ELQKGMGTV 1466
>XP_005276075
          Length = 169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EIQQLMG 7
           E+QQL+G
Sbjct: 147 ELQQLLG 153
>NP_001273598
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 445 EIEKLVGT 452
>NP_001273599
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 113 EIEKLVGT 120
>NP_001273601
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 598 EIEKLVGT 605
>NP_001273600
          Length = 857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 598 EIEKLVGT 605
>NP_861522
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 598 EIEKLVGT 605
>NP_001273597
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 498 EIEKLVGT 505
>NP_001107604
          Length = 2694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1090 EIQSIMGYI 1098
>NP_060164
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EIQQLMGT 8
           EIQ L GT
Sbjct: 719 EIQPLQGT 726
>NP_387467
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++++GT
Sbjct: 243 EIEEILGT 250
>XP_006726609
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EIQQLMG 7
          EIQ+L+G
Sbjct: 78 EIQELLG 84
>XP_006719787
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EIQQLMG 7
          EIQ+L+G
Sbjct: 78 EIQELLG 84
>XP_005269291
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++++GT
Sbjct: 243 EIEEILGT 250
>XP_005251223
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EIQQLM 6
           EIQQLM
Sbjct: 187 EIQQLM 192
>XP_005265784
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 221 EIEKLVGT 228
>XP_005265783
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 445 EIEKLVGT 452
>XP_005265781
          Length = 942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 598 EIEKLVGT 605
>XP_005265778
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EIQQLMGT 8
           EI++L+GT
Sbjct: 598 EIEKLVGT 605
>XP_005246845
          Length = 1624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  EIQQLMGTV 9
          EIQ +MG +
Sbjct: 7  EIQSIMGYI 15
>XP_006712765
          Length = 2679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1062 EIQSIMGYI 1070
>XP_006712764
          Length = 2697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1119 EIQSIMGYI 1127
>XP_005246844
          Length = 2707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1090 EIQSIMGYI 1098
>XP_006712763
          Length = 2716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1119 EIQSIMGYI 1127
>XP_006712762
          Length = 2723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1119 EIQSIMGYI 1127
>XP_006712761
          Length = 2736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EIQQLMGTV 9
            EIQ +MG +
Sbjct: 1119 EIQSIMGYI 1127
>XP_005246712
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EIQQLMGT 8
           EIQ L GT
Sbjct: 719 EIQPLQGT 726
>XP_005246711
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EIQQLMGT 8
           EIQ L GT
Sbjct: 719 EIQPLQGT 726
>XP_006710027
          Length = 2837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  EIQQLMG 7
          EIQ+L+G
Sbjct: 78 EIQELLG 84
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.133    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,303
Number of extensions: 656
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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