Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001025031                                                           17    3301
NP_036466                                                              17    4312
NP_001158238                                                           17    4312
NP_008816                                                              17    4312
XP_005256014                                                           17    4312
XP_006714538                                                           17    4312
NP_055524                                                              16    5631
NP_001135758                                                           16    7355
NP_689997                                                              16    7355
NP_055754                                                              16    7355
NP_078900                                                              16    7355
NP_065202                                                              16    7355
XP_006725017                                                           16    7355
XP_005258292                                                           16    7355
XP_006722483                                                           16    7355
XP_005258291                                                           16    7355
XP_005258290                                                           16    7355
XP_005262685                                                           16    7355
XP_006711144                                                           16    7355
NP_689991                                                              15    9605
NP_775771                                                              15    9605
NP_665739                                                              15    9605
NP_997054                                                              15    9605
NP_001181866                                                           15    9605
NP_055915                                                              15    9605
NP_001181867                                                           15    9605
NP_001229658                                                           15    9605
NP_085135                                                              15    9605
NP_001122312                                                           15    9605
NP_001122311                                                           15    9605
NP_000711                                                              15    9605
NP_055833                                                              15    9605
NP_001186871                                                           15    9605
NP_065171                                                              15    9605
NP_001133                                                              15    9605
NP_001134                                                              15    9605
XP_005258413                                                           15    9605
XP_006720466                                                           15    9605
XP_005254230                                                           15    9605
XP_006720465                                                           15    9605
XP_005254228                                                           15    9605
XP_006717822                                                           15    9605
XP_006717821                                                           15    9605
XP_005269749                                                           15    9605
XP_006717820                                                           15    9605
XP_006715464                                                           15    9605
XP_006715463                                                           15    9605
XP_006715462                                                           15    9605
XP_006715461                                                           15    9605
XP_006715460                                                           15    9605
XP_006715459                                                           15    9605
XP_006715458                                                           15    9605
XP_006715457                                                           15    9605
XP_006715456                                                           15    9605
XP_006714307                                                           15    9605
XP_005262955                                                           15    9605
XP_005262954                                                           15    9605
XP_005262953                                                           15    9605
XP_005262950                                                           15    9605
XP_005265505                                                           15    9605
XP_006713388                                                           15    9605
XP_006711300                                                           15    9605
XP_005245063                                                           15    9605
XP_005245062                                                           15    9605
XP_005245061                                                           15    9605
XP_005245060                                                           15    9605
XP_005245057                                                           15    9605
XP_005245058                                                           15    9605
XP_005245056                                                           15    9605
NP_065081                                                              15    9605
NP_001017415                                                           15    9605
NP_003359                                                              15    9605
NP_001017416                                                           15    9605
>NP_001025031
          Length = 708

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           E+LTPL+ S
Sbjct: 604 EVLTPLASS 612
>NP_036466
          Length = 2058

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EILTPLSM 8
           EILTPL++
Sbjct: 384 EILTPLNV 391
>NP_001158238
          Length = 2789

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    EILTPLSMS 9
            EILTP S S
Sbjct: 1459 EILTPTSSS 1467
>NP_008816
          Length = 3703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    EILTPLSMS 9
            EILTP S S
Sbjct: 2373 EILTPTSSS 2381
>XP_005256014
          Length = 3702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    EILTPLSMS 9
            EILTP S S
Sbjct: 2372 EILTPTSSS 2380
>XP_006714538
          Length = 2035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EILTPLSM 8
           EILTPL++
Sbjct: 384 EILTPLNV 391
>NP_055524
          Length = 3546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EILTPLSMS 9
            E+LTP S S
Sbjct: 3378 EVLTPTSTS 3386
>NP_001135758
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ILTPLSMS 9
            +LTP SMS
Sbjct: 1047 LLTPQSMS 1054
>NP_689997
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           EILTPL
Sbjct: 351 EILTPL 356
>NP_055754
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPLS S
Sbjct: 966 VLTPLSPS 973
>NP_078900
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ILTPLSMS 9
            +LTP SMS
Sbjct: 1047 LLTPQSMS 1054
>NP_065202
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           EILTPL
Sbjct: 223 EILTPL 228
>XP_006725017
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           EILTPL
Sbjct: 183 EILTPL 188
>XP_005258292
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPLS S
Sbjct: 692 VLTPLSPS 699
>XP_006722483
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPLS S
Sbjct: 967 VLTPLSPS 974
>XP_005258291
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPLS S
Sbjct: 967 VLTPLSPS 974
>XP_005258290
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPLS S
Sbjct: 967 VLTPLSPS 974
>XP_005262685
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ILTPLSMS 9
            +LTP SMS
Sbjct: 1069 LLTPQSMS 1076
>XP_006711144
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           EILTPL
Sbjct: 183 EILTPL 188
>NP_689991
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILTPLSM 8
           I+TPL+M
Sbjct: 289 IITPLTM 295
>NP_775771
          Length = 1244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EILTPLS 7
            E+LTP S
Sbjct: 1018 EVLTPFS 1024
>NP_665739
          Length = 1315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 804 ELLTPLA 810
>NP_997054
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 846 ELLTPLA 852
>NP_001181866
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 890 ELLTPLA 896
>NP_055915
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 899 ELLTPLA 905
>NP_001181867
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 837 ELLTPLA 843
>NP_001229658
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ILTPLS 7
           ILTPLS
Sbjct: 419 ILTPLS 424
>NP_085135
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPL +S
Sbjct: 183 VLTPLKVS 190
>NP_001122312
          Length = 2161

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           EI++PL +S
Sbjct: 608 EIMSPLGIS 616
>NP_001122311
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           EI++PL +S
Sbjct: 608 EIMSPLGIS 616
>NP_000711
          Length = 2181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           EI++PL +S
Sbjct: 628 EIMSPLGIS 636
>NP_055833
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>NP_001186871
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1804 ELLGPISMN 1812
>NP_065171
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 185 EVLTPL 190
>NP_001133
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  EILTPL 6
          E+LTPL
Sbjct: 34 EVLTPL 39
>NP_001134
          Length = 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  EILTPL 6
          E+LTPL
Sbjct: 34 EVLTPL 39
>XP_005258413
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPL +S
Sbjct: 184 VLTPLKVS 191
>XP_006720466
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   EILTPLS 7
           E+LTP S
Sbjct: 949 EVLTPFS 955
>XP_005254230
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   EILTPLS 7
           E+LTP S
Sbjct: 949 EVLTPFS 955
>XP_006720465
          Length = 1239

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EILTPLS 7
            E+LTP S
Sbjct: 1013 EVLTPFS 1019
>XP_005254228
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    EILTPLS 7
            E+LTP S
Sbjct: 1024 EVLTPFS 1030
>XP_006717822
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006717821
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_005269749
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006717820
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 431 EVLTPL 436
>XP_006715464
          Length = 2027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>XP_006715463
          Length = 2434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>XP_006715462
          Length = 2452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1780 ELLGPISMN 1788
>XP_006715461
          Length = 2456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1804 ELLGPISMN 1812
>XP_006715460
          Length = 2465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>XP_006715459
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1803 ELLGPISMN 1811
>XP_006715458
          Length = 2476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1804 ELLGPISMN 1812
>XP_006715457
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>XP_006715456
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EILTPLSMS 9
            E+L P+SM+
Sbjct: 1813 ELLGPISMN 1821
>XP_006714307
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ILTPLS 7
           ILTPLS
Sbjct: 201 ILTPLS 206
>XP_005262955
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILTPLSM 8
           I+TPL+M
Sbjct: 289 IITPLTM 295
>XP_005262954
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILTPLSM 8
           I+TPL+M
Sbjct: 222 IITPLTM 228
>XP_005262953
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILTPLSM 8
           I+TPL+M
Sbjct: 240 IITPLTM 246
>XP_005262950
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILTPLSM 8
           I+TPL+M
Sbjct: 289 IITPLTM 295
>XP_005265505
          Length = 2146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           EI++PL +S
Sbjct: 608 EIMSPLGIS 616
>XP_006713388
          Length = 2194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EILTPLSMS 9
           EI++PL +S
Sbjct: 628 EIMSPLGIS 636
>XP_006711300
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 837 ELLTPLA 843
>XP_005245063
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 846 ELLTPLA 852
>XP_005245062
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 846 ELLTPLA 852
>XP_005245061
          Length = 1357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 846 ELLTPLA 852
>XP_005245060
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 890 ELLTPLA 896
>XP_005245057
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 899 ELLTPLA 905
>XP_005245058
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 899 ELLTPLA 905
>XP_005245056
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EILTPLS 7
           E+LTPL+
Sbjct: 899 ELLTPLA 905
>NP_065081
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EILTPL 6
           E+LTPL
Sbjct: 431 EVLTPL 436
>NP_001017415
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPL +S
Sbjct: 556 LLTPLKLS 563
>NP_003359
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPL +S
Sbjct: 556 LLTPLKLS 563
>NP_001017416
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILTPLSMS 9
           +LTPL +S
Sbjct: 556 LLTPLKLS 563
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.125    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 592,975
Number of extensions: 690
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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