Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     869
NP_671714                                                              19     869
XP_006715890                                                           19     869
XP_005250160                                                           19     869
XP_005250159                                                           19     869
NP_003213                                                              18    1935
NP_001171536                                                           17    3301
NP_000379                                                              17    3301
NP_001273903                                                           17    3301
NP_003789                                                              17    3301
XP_005252348                                                           17    3301
XP_005247894                                                           17    3301
XP_006713853                                                           17    3301
XP_005247893                                                           17    3301
XP_006713852                                                           17    3301
NP_001180401                                                           16    5631
NP_001180400                                                           16    5631
NP_001180402                                                           16    5631
NP_001014986                                                           16    5631
NP_004467                                                              16    5631
NP_710163                                                              16    5631
NP_055211                                                              16    5631
NP_001615                                                              16    5631
XP_006718839                                                           16    5631
XP_005252896                                                           16    5631
XP_005266896                                                           16    5631
NP_542198                                                              16    5631
NP_001257903                                                           16    7355
NP_077816                                                              16    7355
NP_695001                                                              16    7355
NP_542138                                                              16    7355
XP_006723606                                                           16    7355
XP_006721269                                                           16    7355
XP_006720682                                                           16    7355
XP_005268318                                                           16    7355
NP_001243034                                                           15    9605
NP_003383                                                              15    9605
NP_659455                                                              15    9605
NP_060899                                                              15    9605
XP_006725524                                                           15    9605
XP_006725523                                                           15    9605
XP_005276828                                                           15    9605
XP_006726279                                                           15    9605
XP_006714722                                                           15    9605
XP_006714721                                                           15    9605
XP_006713387                                                           15    9605
>NP_005742
          Length = 3907

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EFTEIISQF 9
            E TEIISQF
Sbjct: 2816 EVTEIISQF 2824
>NP_671714
          Length = 3899

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EFTEIISQF 9
            E TEIISQF
Sbjct: 2808 EVTEIISQF 2816
>XP_006715890
          Length = 3860

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EFTEIISQF 9
            E TEIISQF
Sbjct: 2769 EVTEIISQF 2777
>XP_005250160
          Length = 3939

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EFTEIISQF 9
            E TEIISQF
Sbjct: 2848 EVTEIISQF 2856
>XP_005250159
          Length = 3952

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EFTEIISQF 9
            E TEIISQF
Sbjct: 2861 EVTEIISQF 2869
>NP_003213
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EFTEIISQ 8
           EFTE++SQ
Sbjct: 361 EFTELLSQ 368
>NP_001171536
          Length = 1088

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFTEIISQF 9
           +F+E+ISQ+
Sbjct: 238 DFSELISQY 246
>NP_000379
          Length = 1078

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFTEIISQF 9
           +F+E+ISQ+
Sbjct: 238 DFSELISQY 246
>NP_001273903
          Length = 718

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EFTEIISQF 9
           EF +I SQF
Sbjct: 189 EFVQIFSQF 197
>NP_003789
          Length = 734

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EFTEIISQF 9
           EF +I SQF
Sbjct: 189 EFVQIFSQF 197
>XP_005252348
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EFTEIISQF 9
           EF +I SQF
Sbjct: 189 EFVQIFSQF 197
>XP_005247894
          Length = 917

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EFTEIISQF 9
          +F+E+ISQ+
Sbjct: 77 DFSELISQY 85
>XP_006713853
          Length = 1078

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFTEIISQF 9
           +F+E+ISQ+
Sbjct: 238 DFSELISQY 246
>XP_005247893
          Length = 1078

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFTEIISQF 9
           +F+E+ISQ+
Sbjct: 238 DFSELISQY 246
>XP_006713852
          Length = 1078

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFTEIISQF 9
           +F+E+ISQ+
Sbjct: 238 DFSELISQY 246
>NP_001180401
          Length = 704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 624 FTEIASKF 631
>NP_001180400
          Length = 735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 624 FTEIASKF 631
>NP_001180402
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 331 FTEIASKF 338
>NP_001014986
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 639 FTEIASKF 646
>NP_004467
          Length = 750

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 639 FTEIASKF 646
>NP_710163
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 331 FTEIASKF 338
>NP_055211
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           + EI+SQF
Sbjct: 258 YVEIVSQF 265
>NP_001615
          Length = 1723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFTEIISQ 8
           +FTEII Q
Sbjct: 699 KFTEIIKQ 706
>XP_006718839
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 622 FTEIASKF 629
>XP_005252896
          Length = 582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           FTEI S+F
Sbjct: 471 FTEIASKF 478
>XP_005266896
          Length = 2131

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EFTEIISQ 8
            +FTEII Q
Sbjct: 1107 KFTEIIKQ 1114
>NP_542198
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTEIISQF 9
           + EI+SQF
Sbjct: 233 YVEIVSQF 240
>NP_001257903
          Length = 5121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EFTEII 6
            EFTEII
Sbjct: 3634 EFTEII 3639
>NP_077816
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FTEIISQF 9
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>NP_695001
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FTEIISQF 9
           F EII QF
Sbjct: 302 FREIIDQF 309
>NP_542138
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FTEIISQF 9
           F EII QF
Sbjct: 301 FREIIDQF 308
>XP_006723606
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   FTEIISQF 9
           F EII QF
Sbjct: 249 FREIIDQF 256
>XP_006721269
          Length = 5138

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EFTEII 6
            EFTEII
Sbjct: 3651 EFTEII 3656
>XP_006720682
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FTEIISQF 9
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>XP_005268318
          Length = 1499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   FTEIISQF 9
           F+E++S+F
Sbjct: 215 FSELVSEF 222
>NP_001243034
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TEIISQF 9
           TEI+ QF
Sbjct: 356 TEIVDQF 362
>NP_003383
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TEIISQF 9
           TEI+ QF
Sbjct: 371 TEIVDQF 377
>NP_659455
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFTEIISQ 8
           EFT I+SQ
Sbjct: 244 EFTCIVSQ 251
>NP_060899
          Length = 2624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2300 EFTDATAQF 2308
>XP_006725524
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2300 EFTDATAQF 2308
>XP_006725523
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2299 EFTDATAQF 2307
>XP_005276828
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2300 EFTDATAQF 2308
>XP_006726279
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2299 EFTDATAQF 2307
>XP_006714722
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2300 EFTDATAQF 2308
>XP_006714721
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    EFTEIISQF 9
            EFT+  +QF
Sbjct: 2299 EFTDATAQF 2307
>XP_006713387
          Length = 365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TEIISQF 9
           TEI+ QF
Sbjct: 356 TEIVDQF 362
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.141    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,760
Number of extensions: 569
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package