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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001265723                                                           17    4312
NP_005963                                                              17    4312
NP_001265724                                                           17    4312
XP_005277701                                                           17    4312
XP_006717608                                                           17    4312
NP_079130                                                              16    5631
XP_006719216                                                           16    5631
NP_000248                                                              16    7355
NP_203752                                                              16    7355
NP_001139381                                                           16    7355
XP_005267754                                                           16    7355
XP_005267753                                                           16    7355
XP_006712877                                                           16    7355
XP_006712876                                                           16    7355
XP_006712875                                                           16    7355
XP_006712874                                                           16    7355
XP_006712873                                                           16    7355
XP_006712872                                                           16    7355
XP_005246976                                                           16    7355
XP_005246975                                                           16    7355
NP_006197                                                              15    9605
NP_002600                                                              15    9605
NP_071328                                                              15    9605
XP_005268521                                                           15    9605
XP_005265800                                                           15    9605
XP_006714103                                                           15    9605
XP_006714102                                                           15    9605

>NP_001265723
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           EFLA K+V
Sbjct: 193 EFLADKVV 200



>NP_005963
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           EFLA K+V
Sbjct: 193 EFLADKVV 200



>NP_001265724
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           EFLA K+V
Sbjct: 193 EFLADKVV 200



>XP_005277701
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           EFLA K+V
Sbjct: 193 EFLADKVV 200



>XP_006717608
          Length = 375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           EFLA K+V
Sbjct: 193 EFLADKVV 200



>NP_079130
          Length = 500

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EFLASKIVS 9
           EFL SK+++
Sbjct: 191 EFLTSKLIA 199



>XP_006719216
          Length = 259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EFLASKIVS 9
           EFL SK+++
Sbjct: 191 EFLTSKLIA 199



>NP_000248
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EFLASKIVS 9
          EF+ +KIVS
Sbjct: 45 EFVKAKIVS 53



>NP_203752
          Length = 1861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 496 KYLASKVVA 504



>NP_001139381
          Length = 1390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 488 KYLASKVVA 496



>XP_005267754
          Length = 1087

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EFLASKIVS 9
          EF+ +KIVS
Sbjct: 45 EFVKAKIVS 53



>XP_005267753
          Length = 1935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EFLASKIVS 9
          EF+ +KIVS
Sbjct: 45 EFVKAKIVS 53



>XP_006712877
          Length = 1677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 312 KYLASKVVA 320



>XP_006712876
          Length = 1783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 418 KYLASKVVA 426



>XP_006712875
          Length = 1826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 461 KYLASKVVA 469



>XP_006712874
          Length = 1836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 471 KYLASKVVA 479



>XP_006712873
          Length = 1861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 496 KYLASKVVA 504



>XP_006712872
          Length = 1861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 496 KYLASKVVA 504



>XP_005246976
          Length = 1864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 499 KYLASKVVA 507



>XP_005246975
          Length = 1871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EFLASKIVS 9
           ++LASK+V+
Sbjct: 506 KYLASKVVA 514



>NP_006197
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 807 EFLASK 812



>NP_002600
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 815 EFLASK 820



>NP_071328
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   EFLASKIV 8
           +FLA KI+
Sbjct: 277 DFLAKKII 284



>XP_005268521
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 751 EFLASK 756



>XP_005265800
          Length = 1089

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 807 EFLASK 812



>XP_006714103
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 829 EFLASK 834



>XP_006714102
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EFLASK 6
           EFLASK
Sbjct: 832 EFLASK 837



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.130    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 261,000
Number of extensions: 373
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)