Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_006714104                                                           19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_062541                                                              17    3301
NP_671494                                                              17    3301
NP_006268                                                              17    3301
NP_055524                                                              17    3301
NP_001161067                                                           17    4312
NP_055139                                                              17    4312
NP_056107                                                              17    4312
NP_001171725                                                           17    4312
NP_001275925                                                           16    5631
NP_005206                                                              16    5631
NP_009162                                                              16    5631
NP_919258                                                              16    5631
NP_002709                                                              16    5631
NP_055031                                                              16    5631
NP_001136065                                                           16    5631
NP_001136066                                                           16    5631
NP_001275505                                                           16    5631
NP_001093881                                                           16    5631
NP_078857                                                              16    5631
XP_005258261                                                           16    5631
XP_006714144                                                           16    5631
XP_005262807                                                           16    5631
XP_005262806                                                           16    5631
XP_006713749                                                           16    5631
NP_004406                                                              16    7355
NP_036213                                                              16    7355
XP_006714638                                                           16    7355
XP_006714637                                                           16    7355
NP_066956                                                              15    9605
NP_982271                                                              15    9605
NP_001153774                                                           15    9605
NP_003886                                                              15    9605
NP_001153778                                                           15    9605
NP_077816                                                              15    9605
NP_996999                                                              15    9605
NP_996994                                                              15    9605
NP_060009                                                              15    9605
NP_001188291                                                           15    9605
XP_005261137                                                           15    9605
XP_006724126                                                           15    9605
XP_006724125                                                           15    9605
XP_006724124                                                           15    9605
XP_005261133                                                           15    9605
XP_006724123                                                           15    9605
XP_006724122                                                           15    9605
XP_006724121                                                           15    9605
XP_006721125                                                           15    9605
XP_005268318                                                           15    9605
XP_005249842                                                           15    9605
XP_005245468                                                           15    9605
XP_006710344                                                           15    9605
XP_006710343                                                           15    9605
XP_006710342                                                           15    9605
NP_001092763                                                           15    9605
NP_006305                                                              15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  EEVVQLNSS 9
          E+VVQLNSS
Sbjct: 36 EKVVQLNSS 44
>XP_006714104
          Length = 832

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  EEVVQLNSS 9
          E+VVQLNSS
Sbjct: 61 EKVVQLNSS 69
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  EEVVQLNSS 9
          E+VVQLNSS
Sbjct: 36 EKVVQLNSS 44
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  EEVVQLNSS 9
          E+VVQLNSS
Sbjct: 58 EKVVQLNSS 66
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  EEVVQLNSS 9
          E+VVQLNSS
Sbjct: 61 EKVVQLNSS 69
>NP_062541
          Length = 1670

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LNS
Sbjct: 479 EEIVRLNS 486
>NP_671494
          Length = 1249

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LNS
Sbjct: 479 EEIVRLNS 486
>NP_006268
          Length = 1697

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LNS
Sbjct: 479 EEIVRLNS 486
>NP_055524
          Length = 3546

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+VQ+NS
Sbjct: 801 EELVQINS 808
>NP_001161067
          Length = 394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EEVVQLNS 8
           EE+ QLNS
Sbjct: 362 EEIYQLNS 369
>NP_055139
          Length = 382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EEVVQLNS 8
           EE+ QLNS
Sbjct: 362 EEIYQLNS 369
>NP_056107
          Length = 1104

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EEV+Q+NS
Sbjct: 778 EEVLQVNS 785
>NP_001171725
          Length = 1114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EEV+Q+NS
Sbjct: 788 EEVLQVNS 795
>NP_001275925
          Length = 660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EE+V +NS+
Sbjct: 45 EEIVNINST 53
>NP_005206
          Length = 1447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EEVVQLNS 8
           EEV+QL S
Sbjct: 277 EEVIQLRS 284
>NP_009162
          Length = 642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           +E++Q+N S
Sbjct: 183 QEIIQMNKS 191
>NP_919258
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EE+V +NS+
Sbjct: 45 EEIVNINST 53
>NP_002709
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   EEVVQLNSS 9
           E+VVQL++S
Sbjct: 335 EDVVQLSAS 343
>NP_055031
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EVVQLNSS 9
          EVVQLN S
Sbjct: 37 EVVQLNLS 44
>NP_001136065
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EVVQLNSS 9
          EVVQLN S
Sbjct: 37 EVVQLNLS 44
>NP_001136066
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  EVVQLNSS 9
          EVVQLN S
Sbjct: 37 EVVQLNLS 44
>NP_001275505
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EEVVQLNSS 9
           EEV QLN +
Sbjct: 350 EEVTQLNEA 358
>NP_001093881
          Length = 971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EEVVQLNSS 9
           EEV QLN +
Sbjct: 350 EEVTQLNEA 358
>NP_078857
          Length = 1140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EEVVQLNSS 9
           EEV QLN +
Sbjct: 470 EEVTQLNEA 478
>XP_005258261
          Length = 1447

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EEVVQLNS 8
           EEV+QL S
Sbjct: 277 EEVIQLRS 284
>XP_006714144
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EE+V +NS+
Sbjct: 45 EEIVNINST 53
>XP_005262807
          Length = 749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EE+V +NS+
Sbjct: 45 EEIVNINST 53
>XP_005262806
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EE+V +NS+
Sbjct: 63 EEIVNINST 71
>XP_006713749
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   EEVVQLNSS 9
           E+VVQL++S
Sbjct: 335 EDVVQLSAS 343
>NP_004406
          Length = 2871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EEVVQLNSS 9
            +E+V+LN S
Sbjct: 1251 DEIVRLNDS 1259
>NP_036213
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           EE+ +LN+S
Sbjct: 494 EEIAKLNNS 502
>XP_006714638
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           EE+ +LN+S
Sbjct: 439 EEIAKLNNS 447
>XP_006714637
          Length = 589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           EE+ +LN+S
Sbjct: 494 EEIAKLNNS 502
>NP_066956
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           EEVVQL+
Sbjct: 548 EEVVQLS 554
>NP_982271
          Length = 1350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 629 EEMVELNA 636
>NP_001153774
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 590 EEMVELNA 597
>NP_003886
          Length = 1612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 629 EEMVELNA 636
>NP_001153778
          Length = 1526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 585 EEMVELNA 592
>NP_077816
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           EEV+ LN++
Sbjct: 910 EEVITLNAT 918
>NP_996999
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EEVVQLNS 8
          EEV+ LN+
Sbjct: 8  EEVIHLNN 15
>NP_996994
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EEVVQLNS 8
          EEV+ LN+
Sbjct: 8  EEVIHLNN 15
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    EVVQLNS 8
            E++Q+NS
Sbjct: 1820 EIIQMNS 1826
>NP_001188291
          Length = 95

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEVVQLNSS 9
          EEV+ +N+S
Sbjct: 86 EEVLSINTS 94
>XP_005261137
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 585 EEMVELNA 592
>XP_006724126
          Length = 1313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 593 EEMVELNA 600
>XP_006724125
          Length = 1313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 593 EEMVELNA 600
>XP_006724124
          Length = 1534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 593 EEMVELNA 600
>XP_005261133
          Length = 1557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 590 EEMVELNA 597
>XP_006724123
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 593 EEMVELNA 600
>XP_006724122
          Length = 1568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 585 EEMVELNA 592
>XP_006724121
          Length = 1576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EEVVQLNS 8
           EE+V+LN+
Sbjct: 593 EEMVELNA 600
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    EVVQLNS 8
            E++Q+NS
Sbjct: 1774 EIIQMNS 1780
>XP_005268318
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEVVQLNSS 9
           EEV+ LN++
Sbjct: 910 EEVITLNAT 918
>XP_005249842
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  EEVVQLNS 8
          EEV+ LN+
Sbjct: 8  EEVIHLNN 15
>XP_005245468
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           EEVVQL+
Sbjct: 548 EEVVQLS 554
>XP_006710344
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           +EVVQ+N
Sbjct: 241 DEVVQIN 247
>XP_006710343
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           +EVVQ+N
Sbjct: 282 DEVVQIN 288
>XP_006710342
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           +EVVQ+N
Sbjct: 282 DEVVQIN 288
>NP_001092763
          Length = 1234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEVVQLNSS 9
           +EVV+LN++
Sbjct: 524 KEVVELNNA 532
>NP_006305
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EEVVQLN 7
           +EVVQ+N
Sbjct: 241 DEVVQIN 247
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286    0.108    0.232 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,032
Number of extensions: 554
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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