Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     509
NP_653080                                                              20     509
XP_005267292                                                           20     509
XP_005267291                                                           20     509
XP_005267290                                                           20     509
NP_001073922                                                           17    2528
NP_899631                                                              17    4312
NP_899630                                                              17    4312
NP_003707                                                              17    4312
XP_006713441                                                           17    4312
XP_006713440                                                           17    4312
XP_006713439                                                           17    4312
XP_006713438                                                           17    4312
XP_006713437                                                           17    4312
XP_006713436                                                           17    4312
XP_006713435                                                           17    4312
XP_006713434                                                           17    4312
XP_006713433                                                           17    4312
XP_006713432                                                           17    4312
XP_006713431                                                           17    4312
XP_006713430                                                           17    4312
XP_006713429                                                           17    4312
XP_006713428                                                           17    4312
XP_006713427                                                           17    4312
XP_006713426                                                           17    4312
XP_006713425                                                           17    4312
NP_001157570                                                           16    5631
NP_004376                                                              16    5631
NP_001611                                                              16    5631
NP_076965                                                              16    5631
XP_006718751                                                           16    5631
XP_006718750                                                           16    5631
XP_005274303                                                           16    5631
XP_006718749                                                           16    5631
XP_005274302                                                           16    5631
XP_005274301                                                           16    5631
XP_005274300                                                           16    5631
XP_005274299                                                           16    5631
XP_005274298                                                           16    5631
XP_005274297                                                           16    5631
NP_775866                                                              16    7355
NP_055939                                                              16    7355
XP_006724233                                                           16    7355
XP_005261457                                                           16    7355
XP_005261456                                                           16    7355
XP_005261455                                                           16    7355
XP_005261454                                                           16    7355
XP_006724232                                                           16    7355
XP_006724231                                                           16    7355
XP_005261453                                                           16    7355
NP_008952                                                              15    9605
NP_001153699                                                           15    9605
NP_002078                                                              15    9605
NP_079413                                                              15    9605
NP_055523                                                              15    9605
XP_005257310                                                           15    9605
XP_006720764                                                           15    9605
XP_005254752                                                           15    9605
XP_006720763                                                           15    9605
XP_006720762                                                           15    9605
XP_005254751                                                           15    9605
XP_006719769                                                           15    9605
>NP_005091
          Length = 1782

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EETTTEMLT 9
            EET TEMLT
Sbjct: 1565 EETATEMLT 1573
>NP_653080
          Length = 1684

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EETTTEMLT 9
            EET TEMLT
Sbjct: 1467 EETATEMLT 1475
>XP_005267292
          Length = 1677

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EETTTEMLT 9
            EET TEMLT
Sbjct: 1460 EETATEMLT 1468
>XP_005267291
          Length = 1684

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EETTTEMLT 9
            EET TEMLT
Sbjct: 1467 EETATEMLT 1475
>XP_005267290
          Length = 1782

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EETTTEMLT 9
            EET TEMLT
Sbjct: 1565 EETATEMLT 1573
>NP_001073922
          Length = 2190

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   EETTTEML 8
           EET TEML
Sbjct: 785 EETRTEML 792
>NP_899631
          Length = 1314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1132 EETVKEMIT 1140
>NP_899630
          Length = 1274

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1092 EETVKEMIT 1100
>NP_003707
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1171 EETVKEMIT 1179
>XP_006713441
          Length = 1125

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 943 EETVKEMIT 951
>XP_006713440
          Length = 1127

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 945 EETVKEMIT 953
>XP_006713439
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 952 EETVKEMIT 960
>XP_006713438
          Length = 1148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 966 EETVKEMIT 974
>XP_006713437
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 972 EETVKEMIT 980
>XP_006713436
          Length = 1164

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           EET  EM+T
Sbjct: 982 EETVKEMIT 990
>XP_006713435
          Length = 1174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 992  EETVKEMIT 1000
>XP_006713434
          Length = 1180

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 998  EETVKEMIT 1006
>XP_006713433
          Length = 1183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1001 EETVKEMIT 1009
>XP_006713432
          Length = 1184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1002 EETVKEMIT 1010
>XP_006713431
          Length = 1190

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1008 EETVKEMIT 1016
>XP_006713430
          Length = 1197

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1015 EETVKEMIT 1023
>XP_006713429
          Length = 1203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1021 EETVKEMIT 1029
>XP_006713428
          Length = 1206

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1024 EETVKEMIT 1032
>XP_006713427
          Length = 1207

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1025 EETVKEMIT 1033
>XP_006713426
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1028 EETVKEMIT 1036
>XP_006713425
          Length = 1213

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EETTTEMLT 9
            EET  EM+T
Sbjct: 1031 EETVKEMIT 1039
>NP_001157570
          Length = 1642

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EETTTE 6
            EETTTE
Sbjct: 1166 EETTTE 1171
>NP_004376
          Length = 3396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    EETTTE 6
            EETTTE
Sbjct: 1166 EETTTE 1171
>NP_001611
          Length = 5890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>NP_076965
          Length = 149

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_006718751
          Length = 3489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_006718750
          Length = 4001

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274303
          Length = 4506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_006718749
          Length = 4596

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274302
          Length = 5438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274301
          Length = 5762

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274300
          Length = 5762

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274299
          Length = 5762

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274298
          Length = 5890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>XP_005274297
          Length = 5890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EETTTEML 8
          EETT E+L
Sbjct: 4  EETTRELL 11
>NP_775866
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   EETTTEML 8
           +++TTEML
Sbjct: 835 QDSTTEML 842
>NP_055939
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 103 EETNAEML 110
>XP_006724233
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 103 EETNAEML 110
>XP_005261457
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 129 EETNAEML 136
>XP_005261456
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 103 EETNAEML 110
>XP_005261455
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 103 EETNAEML 110
>XP_005261454
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 129 EETNAEML 136
>XP_006724232
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 126 EETNAEML 133
>XP_006724231
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 129 EETNAEML 136
>XP_005261453
          Length = 604

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EETTTEML 8
           EET  EML
Sbjct: 129 EETNAEML 136
>NP_008952
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  ETTTEML 8
          ETT EML
Sbjct: 17 ETTEEML 23
>NP_001153699
          Length = 2330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>NP_002078
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           E  TT++LT
Sbjct: 264 ENATTDLLT 272
>NP_079413
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>NP_055523
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ETTTEML 8
           ETT EML
Sbjct: 484 ETTQEML 490
>XP_005257310
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EETTTEMLT 9
           E  TT++LT
Sbjct: 264 ENATTDLLT 272
>XP_006720764
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>XP_005254752
          Length = 2357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1222 EKTTTEEL 1229
>XP_006720763
          Length = 2395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>XP_006720762
          Length = 2397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>XP_005254751
          Length = 2407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EETTTEML 8
            E+TTTE L
Sbjct: 1308 EKTTTEEL 1315
>XP_006719769
          Length = 2209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ETTTEML 8
           ETT EML
Sbjct: 484 ETTQEML 490
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286    0.101    0.230 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 403,177
Number of extensions: 734
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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