Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
XP_006726436                                                           18    1935
XP_006726410                                                           18    1935
XP_006711784                                                           18    1935
XP_006711719                                                           18    1935
XP_006711718                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
XP_006711164                                                           18    1935
XP_005276153                                                           18    1935
XP_003846805                                                           18    1935
XP_006710122                                                           18    1935
NP_055524                                                              16    5631
NP_060899                                                              16    5631
XP_006725524                                                           16    5631
XP_006725523                                                           16    5631
XP_005276828                                                           16    5631
XP_006726279                                                           16    5631
XP_006714722                                                           16    5631
XP_006714721                                                           16    5631
NP_056051                                                              16    7355
XP_006714219                                                           16    7355
XP_006714218                                                           16    7355
XP_006714217                                                           16    7355
XP_006714216                                                           16    7355
NP_001135451                                                           15    9605
NP_005648                                                              15    9605
NP_001135452                                                           15    9605
XP_006720729                                                           15    9605
XP_005254692                                                           15    9605
XP_005254691                                                           15    9605
XP_006716126                                                           15    9605
XP_005250566                                                           15    9605
XP_005250565                                                           15    9605
NP_001120829                                                           15    9605
NP_001120830                                                           15    9605
NP_065165                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2139 EESASLLTM 2147
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2245 EESASLLTM 2253
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2245 EESASLLTM 2253
>XP_006726436
          Length = 178

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EESAFLLTM 9
          EESA LLTM
Sbjct: 23 EESASLLTM 31
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 1986 EESASLLTM 1994
>XP_006711784
          Length = 178

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EESAFLLTM 9
          EESA LLTM
Sbjct: 23 EESASLLTM 31
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2201 EESASLLTM 2209
>XP_006711718
          Length = 1436

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 1252 EESASLLTM 1260
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2201 EESASLLTM 2209
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2310 EESASLLTM 2318
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2244 EESASLLTM 2252
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2245 EESASLLTM 2253
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2248 EESASLLTM 2256
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2289 EESASLLTM 2297
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2298 EESASLLTM 2306
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2310 EESASLLTM 2318
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2311 EESASLLTM 2319
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2408 EESASLLTM 2416
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2408 EESASLLTM 2416
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2328 EESASLLTM 2336
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2408 EESASLLTM 2416
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2369 EESASLLTM 2377
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2408 EESASLLTM 2416
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2407 EESASLLTM 2415
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 2408 EESASLLTM 2416
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EESA LLTM
Sbjct: 1986 EESASLLTM 1994
>XP_005276153
          Length = 267

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EESAFLLTM 9
           EESA LLTM
Sbjct: 202 EESASLLTM 210
>XP_003846805
          Length = 306

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EESAFLLTM 9
           EESA LLTM
Sbjct: 241 EESASLLTM 249
>XP_006710122
          Length = 126

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  EESAFLLTM 9
          EESA LLTM
Sbjct: 23 EESASLLTM 31
>NP_055524
          Length = 3546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            EES FLL++
Sbjct: 2455 EESQFLLSL 2463
>NP_060899
          Length = 2624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2282 DEQAFILTL 2290
>XP_006725524
          Length = 2584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2282 DEQAFILTL 2290
>XP_006725523
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2281 DEQAFILTL 2289
>XP_005276828
          Length = 2584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2282 DEQAFILTL 2290
>XP_006726279
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2281 DEQAFILTL 2289
>XP_006714722
          Length = 2584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2282 DEQAFILTL 2290
>XP_006714721
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EESAFLLTM 9
            +E AF+LT+
Sbjct: 2281 DEQAFILTL 2289
>NP_056051
          Length = 1469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EESAFLL 7
           EESAF+L
Sbjct: 674 EESAFVL 680
>XP_006714219
          Length = 806

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EESAFLL 7
           EESAF+L
Sbjct: 240 EESAFVL 246
>XP_006714218
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EESAFLL 7
          EESAF+L
Sbjct: 45 EESAFVL 51
>XP_006714217
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EESAFLL 7
           EESAF+L
Sbjct: 227 EESAFVL 233
>XP_006714216
          Length = 1026

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EESAFLL 7
           EESAF+L
Sbjct: 240 EESAFVL 246
>NP_001135451
          Length = 1975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AFLLTM 9
            AFLLTM
Sbjct: 1736 AFLLTM 1741
>NP_005648
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AFLLTM 9
            AFLLTM
Sbjct: 1733 AFLLTM 1738
>NP_001135452
          Length = 1977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AFLLTM 9
            AFLLTM
Sbjct: 1738 AFLLTM 1743
>XP_006720729
          Length = 940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AFLLTM 9
           AFLLTM
Sbjct: 701 AFLLTM 706
>XP_005254692
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AFLLTM 9
           AFLLTM
Sbjct: 778 AFLLTM 783
>XP_005254691
          Length = 1972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    AFLLTM 9
            AFLLTM
Sbjct: 1733 AFLLTM 1738
>XP_006716126
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 561 SAFLLTI 567
>XP_005250566
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>XP_005250565
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>NP_001120829
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 604 SAFLLTI 610
>NP_001120830
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 600 SAFLLTI 606
>NP_065165
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SAFLLTM 9
           SAFLLT+
Sbjct: 600 SAFLLTI 606
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.127    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,599
Number of extensions: 577
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package