Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_570711                                                              21     175
NP_570712                                                              21     175
NP_570714                                                              21     175
NP_570713                                                              21     175
NP_570716                                                              21     175
NP_000235                                                              21     175
NP_570715                                                              21     175
XP_006718620                                                           21     175
XP_005274059                                                           21     175
XP_005274060                                                           21     175
XP_005274058                                                           21     175
XP_005276387                                                           17    2528
XP_005272420                                                           17    2528
XP_005250117                                                           17    2528
XP_005276080                                                           17    2528
NP_003583                                                              17    2528
NP_056993                                                              17    3301
NP_003384                                                              17    3301
NP_009049                                                              16    5631
XP_006725221                                                           16    5631
XP_006714558                                                           16    5631
NP_001129476                                                           16    7355
NP_001116203                                                           16    7355
NP_056056                                                              16    7355
NP_057057                                                              16    7355
NP_203751                                                              16    7355
XP_005261319                                                           16    7355
XP_006724151                                                           16    7355
XP_006724150                                                           16    7355
XP_006724149                                                           16    7355
XP_006724148                                                           16    7355
XP_006724147                                                           16    7355
XP_006724146                                                           16    7355
XP_006724145                                                           16    7355
XP_006724144                                                           16    7355
XP_006718643                                                           16    7355
XP_006714456                                                           16    7355
XP_005263376                                                           16    7355
NP_079042                                                              15    9605
NP_000354                                                              15    9605
NP_570897                                                              15    9605
NP_001193945                                                           15    9605
NP_001014364                                                           15    9605
NP_001121186                                                           15    9605
NP_002840                                                              15    9605
NP_001193944                                                           15    9605
NP_078779                                                              15    9605
NP_660337                                                              15    9605
NP_001035059                                                           15    9605
NP_001265168                                                           15    9605
NP_001265165                                                           15    9605
NP_060598                                                              15    9605
NP_116170                                                              15    9605
NP_008837                                                              15    9605
NP_001265167                                                           15    9605
XP_006720926                                                           15    9605
XP_006720925                                                           15    9605
XP_006720924                                                           15    9605
XP_006720923                                                           15    9605
XP_005255218                                                           15    9605
XP_005255217                                                           15    9605
XP_006714108                                                           15    9605
XP_005265813                                                           15    9605
XP_005265812                                                           15    9605
XP_005265811                                                           15    9605
XP_006714107                                                           15    9605
XP_005265809                                                           15    9605
XP_005264624                                                           15    9605
XP_006710871                                                           15    9605
XP_006710201                                                           15    9605
NP_065773                                                              15    9605
>NP_570711
          Length = 610

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 204 EDRRGQTVN 212
>NP_570712
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>NP_570714
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>NP_570713
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>NP_570716
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>NP_000235
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>NP_570715
          Length = 615

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 209 EDRRGQTVN 217
>XP_006718620
          Length = 610

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 204 EDRRGQTVN 212
>XP_005274059
          Length = 610

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 204 EDRRGQTVN 212
>XP_005274060
          Length = 610

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 204 EDRRGQTVN 212
>XP_005274058
          Length = 610

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EERRGQTVN 9
           E+RRGQTVN
Sbjct: 204 EDRRGQTVN 212
>XP_005276387
          Length = 262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EERRGQTVN 9
          +ERR QT N
Sbjct: 24 QERRAQTAN 32
>XP_005272420
          Length = 262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EERRGQTVN 9
          +ERR QT N
Sbjct: 24 QERRAQTAN 32
>XP_005250117
          Length = 776

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EERRGQTVN 9
           +ER G+T+N
Sbjct: 189 KERNGETIN 197
>XP_005276080
          Length = 262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EERRGQTVN 9
          +ERR QT N
Sbjct: 24 QERRAQTAN 32
>NP_003583
          Length = 776

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EERRGQTVN 9
           +ER G+T+N
Sbjct: 189 KERNGETIN 197
>NP_056993
          Length = 2371

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    EERRGQTV 8
            EERRGQ +
Sbjct: 1277 EERRGQVL 1284
>NP_003384
          Length = 351

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EERRGQTVN 9
           EERR +TV+
Sbjct: 299 EERRAETVS 307
>NP_009049
          Length = 3097

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    RRGQTV 8
            RRGQTV
Sbjct: 1678 RRGQTV 1683
>XP_006725221
          Length = 165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RRGQTV 8
          RRGQTV
Sbjct: 9  RRGQTV 14
>XP_006714558
          Length = 2612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    RRGQTV 8
            RRGQTV
Sbjct: 1193 RRGQTV 1198
>NP_001129476
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>NP_001116203
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>NP_056056
          Length = 2002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>NP_057057
          Length = 123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          +E+RG T+N
Sbjct: 29 KEKRGWTLN 37
>NP_203751
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RRGQTVN 9
           RRG+T+N
Sbjct: 151 RRGRTLN 157
>XP_005261319
          Length = 2002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724151
          Length = 2063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724150
          Length = 2154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724149
          Length = 2168

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724148
          Length = 2176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724147
          Length = 2187

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724146
          Length = 2193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724145
          Length = 2210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006724144
          Length = 2214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          EER+ +T+N
Sbjct: 2  EERKHETMN 10
>XP_006718643
          Length = 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EERRGQTVN 9
          +E+RG T+N
Sbjct: 29 KEKRGWTLN 37
>XP_006714456
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RRGQTVN 9
           RRG+T+N
Sbjct: 151 RRGRTLN 157
>XP_005263376
          Length = 1143

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RRGQTVN 9
           RRG+T+N
Sbjct: 151 RRGRTLN 157
>NP_079042
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RRGQTVN 9
           RRG T+N
Sbjct: 263 RRGNTLN 269
>NP_000354
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  EERRGQ 6
          EERRG+
Sbjct: 66 EERRGE 71
>NP_570897
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  EERRGQTVN 9
          +ERRG  V+
Sbjct: 89 QERRGSNVS 97
>NP_001193945
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 128 QERRGSNVS 136
>NP_001014364
          Length = 2391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    EERRGQTVN 9
            E   GQT+N
Sbjct: 1237 ETTHGQTIN 1245
>NP_001121186
          Length = 2405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EERRG+
Sbjct: 1709 EERRGE 1714
>NP_002840
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 334 QERRGSNVS 342
>NP_001193944
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 222 QERRGSNVS 230
>NP_078779
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EERRG+
Sbjct: 1709 EERRGE 1714
>NP_660337
          Length = 1748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 709 EQRRGQ 714
>NP_001035059
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 208 QERRGSNVS 216
>NP_001265168
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 184 QERRGSNVS 192
>NP_001265165
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 208 QERRGSNVS 216
>NP_060598
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RGQTVN 9
           RGQT+N
Sbjct: 279 RGQTLN 284
>NP_116170
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 240 QERRGSNVS 248
>NP_008837
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 240 QERRGSNVS 248
>NP_001265167
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EERRGQTVN 9
           +ERRG  V+
Sbjct: 216 QERRGSNVS 224
>XP_006720926
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 710 EQRRGQ 715
>XP_006720925
          Length = 1674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 710 EQRRGQ 715
>XP_006720924
          Length = 1679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 638 EQRRGQ 643
>XP_006720923
          Length = 1738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 710 EQRRGQ 715
>XP_005255218
          Length = 1750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 709 EQRRGQ 714
>XP_005255217
          Length = 1751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           E+RRGQ
Sbjct: 710 EQRRGQ 715
>XP_006714108
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           EER+GQ
Sbjct: 908 EERKGQ 913
>XP_005265813
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           EER+GQ
Sbjct: 932 EERKGQ 937
>XP_005265812
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           EER+GQ
Sbjct: 940 EERKGQ 945
>XP_005265811
          Length = 1175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           EER+GQ
Sbjct: 964 EERKGQ 969
>XP_006714107
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EER+GQ
Sbjct: 1022 EERKGQ 1027
>XP_005265809
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EER+GQ
Sbjct: 1022 EERKGQ 1027
>XP_005264624
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RRGQTVN 9
           RRG T+N
Sbjct: 107 RRGNTLN 113
>XP_006710871
          Length = 2406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EERRG+
Sbjct: 1709 EERRGE 1714
>XP_006710201
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   EERRGQ 6
           EERRG+
Sbjct: 313 EERRGE 318
>NP_065773
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    EERRGQ 6
            EER+GQ
Sbjct: 1022 EERKGQ 1027
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.123    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 599,777
Number of extensions: 859
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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