Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721991                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_006002                                                              17    3301
NP_001277144                                                           16    5631
NP_001277143                                                           16    5631
NP_001319                                                              16    5631
NP_001012632                                                           16    5631
NP_001077383                                                           16    5631
NP_001004441                                                           16    5631
NP_001320                                                              16    5631
NP_073713                                                              16    5631
NP_001073922                                                           16    5631
XP_005269629                                                           16    5631
XP_005269628                                                           16    5631
XP_005269627                                                           16    5631
XP_005269626                                                           16    5631
XP_006717706                                                           16    5631
XP_005269625                                                           16    5631
XP_005269624                                                           16    5631
XP_006717705                                                           16    5631
XP_005269622                                                           16    5631
XP_005269621                                                           16    5631
XP_006717704                                                           16    5631
XP_005269619                                                           16    5631
XP_005269618                                                           16    5631
XP_005272045                                                           16    5631
XP_006714664                                                           16    5631
XP_006714662                                                           16    5631
XP_005272320                                                           16    5631
XP_005272319                                                           16    5631
XP_005272318                                                           16    5631
NP_001070993                                                           16    7355
NP_071930                                                              16    7355
XP_005265457                                                           16    7355
NP_001070994                                                           16    7355
NP_116253                                                              15    9605
NP_001275514                                                           15    9605
NP_741982                                                              15    9605
NP_001275739                                                           15    9605
NP_203744                                                              15    9605
NP_115942                                                              15    9605
NP_116246                                                              15    9605
XP_006724408                                                           15    9605
XP_005261849                                                           15    9605
XP_005261848                                                           15    9605
XP_005254200                                                           15    9605
NP_057558                                                              15    9605
NP_061739                                                              15    9605
NP_114400                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1561 EEFKALKTL 1569
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1582 EEFKALKTL 1590
>XP_006721991
          Length = 1632

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1592 EEFKALKTL 1600
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1592 EEFKALKTL 1600
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1592 EEFKALKTL 1600
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1561 EEFKALKTL 1569
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1571 EEFKALKTL 1579
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1592 EEFKALKTL 1600
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1579 EEFKALKTL 1587
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1582 EEFKALKTL 1590
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EEFKALKML 9
            EEFKALK L
Sbjct: 1592 EEFKALKTL 1600
>NP_006002
          Length = 375

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   EFKALKML 9
           EFKALK L
Sbjct: 351 EFKALKSL 358
>NP_001277144
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>NP_001277143
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>NP_001319
          Length = 440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EEFKALKML 9
          E+FKAL+++
Sbjct: 87 EKFKALRII 95
>NP_001012632
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EEFKALKML 9
          E+FKAL+++
Sbjct: 76 EKFKALRII 84
>NP_001077383
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>NP_001004441
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           +EFK+ KML
Sbjct: 489 KEFKSKKML 497
>NP_001320
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>NP_073713
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 633 EKFKALRVI 641
>NP_001073922
          Length = 2190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EEFKALKML 9
           EE+  LKML
Sbjct: 758 EEYPTLKML 766
>XP_005269629
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269628
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269627
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269626
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_006717706
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269625
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269624
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_006717705
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269622
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269621
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_006717704
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269619
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005269618
          Length = 445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EEFKALKML 9
           E+FKAL+++
Sbjct: 93  EKFKALRVI 101
>XP_005272045
          Length = 156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEFKALKML 9
          E F+A++ML
Sbjct: 18 ERFRAMRML 26
>XP_006714664
          Length = 175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EEFKALKML 9
          E F+A++ML
Sbjct: 37 ERFRAMRML 45
>XP_006714662
          Length = 514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           +EFK+ KML
Sbjct: 489 KEFKSKKML 497
>XP_005272320
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EEFKALKML 9
          E+FKAL+++
Sbjct: 76 EKFKALRII 84
>XP_005272319
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EEFKALKML 9
          E+FKAL+++
Sbjct: 76 EKFKALRII 84
>XP_005272318
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  EEFKALKML 9
          E+FKAL+++
Sbjct: 87 EKFKALRII 95
>NP_001070993
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EEFKALK 7
           EEF ALK
Sbjct: 403 EEFSALK 409
>NP_071930
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EEFKALK 7
           EEF ALK
Sbjct: 403 EEFSALK 409
>XP_005265457
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EEFKALK 7
           EEF ALK
Sbjct: 378 EEFSALK 384
>NP_001070994
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   EEFKALK 7
           EEF ALK
Sbjct: 403 EEFSALK 409
>NP_116253
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           E+FK ++ML
Sbjct: 94  EDFKYVRML 102
>NP_001275514
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FKALKML 9
           +KALKM+
Sbjct: 236 YKALKMM 242
>NP_741982
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FKALKML 9
           +KALKM+
Sbjct: 236 YKALKMM 242
>NP_001275739
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           + F+A+KML
Sbjct: 377 KHFQAMKML 385
>NP_203744
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFKALKML 9
           +FK +KML
Sbjct: 838 KFKTMKML 845
>NP_115942
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           E+ KALKM+
Sbjct: 224 EKQKALKMI 232
>NP_116246
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FKALKML 9
           +KALKM+
Sbjct: 236 YKALKMM 242
>XP_006724408
          Length = 788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFKALKML 9
           +FK +KML
Sbjct: 763 KFKTMKML 770
>XP_005261849
          Length = 870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFKALKML 9
           +FK +KML
Sbjct: 845 KFKTMKML 852
>XP_005261848
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EFKALKML 9
           +FK +KML
Sbjct: 847 KFKTMKML 854
>XP_005254200
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FKALKML 9
           +KALKM+
Sbjct: 236 YKALKMM 242
>NP_057558
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EEFKALKML 9
          EEFK  K+L
Sbjct: 27 EEFKQEKLL 35
>NP_061739
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           E+F+ LK+L
Sbjct: 523 EQFRDLKLL 531
>NP_114400
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EEFKALKML 9
           E+F+ LK+L
Sbjct: 523 EQFRDLKLL 531
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.136    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 353,802
Number of extensions: 566
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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