Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              19     665
XP_005248577                                                           19     665
XP_005248576                                                           19     665
NP_060107                                                              17    3301
NP_001191349                                                           17    3301
NP_001193665                                                           17    3301
NP_061327                                                              17    3301
NP_004287                                                              17    3301
NP_001191345                                                           17    3301
NP_057227                                                              17    3301
NP_001191348                                                           17    3301
NP_001191351                                                           17    3301
NP_001191350                                                           17    3301
NP_001191347                                                           17    3301
NP_001191346                                                           17    3301
NP_001191353                                                           17    3301
XP_006720396                                                           17    3301
XP_006720395                                                           17    3301
XP_006720394                                                           17    3301
XP_006720393                                                           17    3301
XP_006720392                                                           17    3301
XP_006720391                                                           17    3301
XP_005268293                                                           17    3301
XP_005268292                                                           17    3301
XP_005268291                                                           17    3301
XP_006720390                                                           17    3301
XP_006716853                                                           17    3301
XP_006716852                                                           17    3301
XP_006716851                                                           17    3301
XP_006716850                                                           17    3301
XP_006716849                                                           17    3301
XP_006716848                                                           17    3301
XP_006716847                                                           17    3301
NP_001018048                                                           17    4312
NP_056001                                                              17    4312
NP_150648                                                              17    4312
NP_001968                                                              17    4312
NP_060117                                                              16    5631
NP_055023                                                              16    7355
NP_000160                                                              16    7355
NP_057717                                                              16    7355
NP_066013                                                              16    7355
XP_005255408                                                           16    7355
XP_005255409                                                           16    7355
XP_006720685                                                           16    7355
NP_071410                                                              15    9605
NP_001186562                                                           15    9605
NP_872590                                                              15    9605
NP_002583                                                              15    9605
NP_002290                                                              15    9605
NP_680481                                                              15    9605
NP_680480                                                              15    9605
NP_003794                                                              15    9605
NP_062830                                                              15    9605
XP_005261505                                                           15    9605
XP_006724260                                                           15    9605
XP_005261504                                                           15    9605
XP_006722097                                                           15    9605
NP_055152                                                              15    9605
>NP_005912
          Length = 1512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDIITIQQD 9
            EDII IQQD
Sbjct: 1214 EDIIIIQQD 1222
>XP_005248577
          Length = 1349

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDIITIQQD 9
            EDII IQQD
Sbjct: 1051 EDIIIIQQD 1059
>XP_005248576
          Length = 1375

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    EDIITIQQD 9
            EDII IQQD
Sbjct: 1077 EDIIIIQQD 1085
>NP_060107
          Length = 1099

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 240 EEIITLQQ 247
>NP_001191349
          Length = 435

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001193665
          Length = 372

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EDIITIQQ 8
          EDI+TI Q
Sbjct: 48 EDIVTISQ 55
>NP_061327
          Length = 339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EDIITIQQ 8
          EDI+TI Q
Sbjct: 48 EDIVTISQ 55
>NP_004287
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191345
          Length = 490

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_057227
          Length = 370

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  EDIITIQQ 8
          EDI+TI Q
Sbjct: 48 EDIVTISQ 55
>NP_001191348
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191351
          Length = 430

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191350
          Length = 448

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191347
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191346
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>NP_001191353
          Length = 490

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720396
          Length = 435

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720395
          Length = 448

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720394
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720393
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720392
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720391
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_005268293
          Length = 472

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_005268292
          Length = 475

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_005268291
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006720390
          Length = 499

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  EDIITIQQD 9
          EDIIT  QD
Sbjct: 30 EDIITKMQD 38
>XP_006716853
          Length = 913

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 268 EEIITLQQ 275
>XP_006716852
          Length = 933

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 268 EEIITLQQ 275
>XP_006716851
          Length = 1008

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 127 EEIITLQQ 134
>XP_006716850
          Length = 1121

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 240 EEIITLQQ 247
>XP_006716849
          Length = 1125

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 268 EEIITLQQ 275
>XP_006716848
          Length = 1127

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 268 EEIITLQQ 275
>XP_006716847
          Length = 1149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           E+IIT+QQ
Sbjct: 268 EEIITLQQ 275
>NP_001018048
          Length = 3069

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    EDIITIQ 7
            EDIIT+Q
Sbjct: 1047 EDIITLQ 1053
>NP_056001
          Length = 3095

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    EDIITIQ 7
            EDIIT+Q
Sbjct: 1047 EDIITLQ 1053
>NP_150648
          Length = 3174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    EDIITIQ 7
            EDIIT+Q
Sbjct: 1047 EDIITLQ 1053
>NP_001968
          Length = 957

 Score = 16.5 bits (31), Expect =  4312
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   EDIITIQQD 9
           ED++ +Q+D
Sbjct: 443 EDVLPVQED 451
>NP_060117
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  DIITIQQD 9
          +++T+QQD
Sbjct: 85 NVVTLQQD 92
>NP_055023
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   EDIITIQQD 9
           ED+  +Q+D
Sbjct: 174 EDVAVVQED 182
>NP_000160
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EDIITIQQD 9
           +D+I I QD
Sbjct: 314 KDVIAINQD 322
>NP_057717
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          ED++T+ +D
Sbjct: 35 EDMVTVVED 43
>NP_066013
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           +D+IT+Q+
Sbjct: 938 QDVITLQE 945
>XP_005255408
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          ED++T+ +D
Sbjct: 35 EDMVTVVED 43
>XP_005255409
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          ED++T+ +D
Sbjct: 35 EDMVTVVED 43
>XP_006720685
          Length = 665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   EDIITIQQ 8
           +D+IT+Q+
Sbjct: 353 QDVITLQE 360
>NP_071410
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          E+ +T++QD
Sbjct: 54 EEQVTVEQD 62
>NP_001186562
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          E+ +T++QD
Sbjct: 54 EEQVTVEQD 62
>NP_872590
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          EDIIT++ +
Sbjct: 85 EDIITLRAE 93
>NP_002583
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EDIITIQQD 9
          EDIIT++ +
Sbjct: 85 EDIITLRAE 93
>NP_002290
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    EDIITIQ 7
            ED++T+Q
Sbjct: 1434 EDLVTLQ 1440
>NP_680481
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
>NP_680480
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
>NP_003794
          Length = 1685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    DIITIQQ 8
            D++TIQ+
Sbjct: 1580 DVVTIQE 1586
>NP_062830
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    DIITIQQ 8
            D++TIQ+
Sbjct: 1484 DVVTIQE 1490
>XP_005261505
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
>XP_006724260
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
>XP_005261504
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
>XP_006722097
          Length = 1862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    DIITIQQD 9
            DI+T Q+D
Sbjct: 1390 DILTTQRD 1397
>NP_055152
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   EDIITIQ 7
           +DIIT+Q
Sbjct: 153 QDIITLQ 159
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.138    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 491,681
Number of extensions: 1142
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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