Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138390                                                           18    1135
NP_001138386                                                           18    1135
NP_001138387                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138388                                                           18    1135
NP_001138391                                                           18    1135
NP_001138385                                                           18    1135
NP_075418                                                              18    1135
XP_006717776                                                           18    1135
XP_006717775                                                           18    1135
XP_006717774                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 394 EAVTVAVKM 402
>NP_001138390
          Length = 704

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 393 EAVTVAVKM 401
>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 398 EAVTVAVKM 406
>NP_001138387
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 421 EAVTVAVKM 429
>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 510 EAVTVAVKM 518
>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 511 EAVTVAVKM 519
>NP_001138388
          Length = 706

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 395 EAVTVAVKM 403
>NP_001138391
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 422 EAVTVAVKM 430
>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 511 EAVTVAVKM 519
>NP_075418
          Length = 732

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 421 EAVTVAVKM 429
>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 529 EAVTVAVKM 537
>XP_006717775
          Length = 726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 415 EAVTVAVKM 423
>XP_006717774
          Length = 752

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 441 EAVTVAVKM 449
>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 530 EAVTVAVKM 538
>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 527 EAVTVAVKM 535
>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAVTVVVKM 9
           EAVTV VKM
Sbjct: 528 EAVTVAVKM 536
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.125    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 202,207
Number of extensions: 157
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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