Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              18    1935
NP_653080                                                              18    1935
XP_005267292                                                           18    1935
XP_005267291                                                           18    1935
XP_005267290                                                           18    1935
NP_003651                                                              17    4312
XP_006723513                                                           17    4312
NP_037528                                                              16    5631
NP_001269970                                                           16    5631
NP_001269971                                                           16    5631
XP_005261006                                                           16    5631
XP_006724055                                                           16    5631
NP_001207404                                                           15    9605
NP_001207405                                                           15    9605
NP_001207407                                                           15    9605
NP_001207406                                                           15    9605
NP_001207402                                                           15    9605
NP_003616                                                              15    9605
NP_001269465                                                           15    9605
NP_001207403                                                           15    9605
NP_588616                                                              15    9605
NP_001137160                                                           15    9605
NP_003617                                                              15    9605
NP_803172                                                              15    9605
XP_005254204                                                           15    9605
XP_005254202                                                           15    9605
XP_005254201                                                           15    9605
XP_006719733                                                           15    9605
XP_006719732                                                           15    9605
XP_006719731                                                           15    9605
XP_006719730                                                           15    9605
XP_006719729                                                           15    9605
XP_006719728                                                           15    9605
XP_006719727                                                           15    9605
XP_006719726                                                           15    9605
XP_006719725                                                           15    9605
XP_006719724                                                           15    9605
XP_006719723                                                           15    9605
XP_006719722                                                           15    9605
XP_006719721                                                           15    9605
XP_006719720                                                           15    9605
XP_006719719                                                           15    9605
XP_006719718                                                           15    9605
XP_006718787                                                           15    9605
XP_006718786                                                           15    9605
XP_006718785                                                           15    9605
XP_006718784                                                           15    9605
XP_006718783                                                           15    9605
XP_006718782                                                           15    9605
XP_006718781                                                           15    9605
XP_006718780                                                           15    9605
XP_006718779                                                           15    9605
XP_006718778                                                           15    9605
XP_005245610                                                           15    9605
XP_006711654                                                           15    9605
XP_006711652                                                           15    9605
XP_006711651                                                           15    9605
XP_006711650                                                           15    9605
XP_006711649                                                           15    9605
XP_006711648                                                           15    9605
XP_006711647                                                           15    9605
>NP_005091
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQ AQKSA
Sbjct: 861 EAQQAQKSA 869
>NP_653080
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQ AQKSA
Sbjct: 763 EAQQAQKSA 771
>XP_005267292
          Length = 1677

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQ AQKSA
Sbjct: 756 EAQQAQKSA 764
>XP_005267291
          Length = 1684

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQ AQKSA
Sbjct: 763 EAQQAQKSA 771
>XP_005267290
          Length = 1782

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQ AQKSA
Sbjct: 861 EAQQAQKSA 869
>NP_003651
          Length = 1194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQLAQ+ A
Sbjct: 375 EAQLAQRVA 383
>XP_006723513
          Length = 1185

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EAQLAQ+ A
Sbjct: 375 EAQLAQRVA 383
>NP_037528
          Length = 1055

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EAQLAQKS 8
           +AQLAQK+
Sbjct: 704 DAQLAQKA 711
>NP_001269970
          Length = 1125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EAQLAQKS 8
           +AQLAQK+
Sbjct: 704 DAQLAQKA 711
>NP_001269971
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EAQLAQKS 8
           +AQLAQK+
Sbjct: 704 DAQLAQKA 711
>XP_005261006
          Length = 721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EAQLAQKS 8
           +AQLAQK+
Sbjct: 300 DAQLAQKA 307
>XP_006724055
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   EAQLAQKS 8
           +AQLAQK+
Sbjct: 405 DAQLAQKA 412
>NP_001207404
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>NP_001207405
          Length = 1251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>NP_001207407
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 311 EAELAQRIA 319
>NP_001207406
          Length = 1156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 336 EAELAQRIA 344
>NP_001207402
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>NP_003616
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>NP_001269465
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 257 EAELAQRIA 265
>NP_001207403
          Length = 1232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 392 EAELAQRIA 400
>NP_588616
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EAQLAQK 7
           EAQLAQ+
Sbjct: 923 EAQLAQE 929
>NP_001137160
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    EAQLAQK 7
            EAQLAQ+
Sbjct: 1006 EAQLAQE 1012
>NP_003617
          Length = 1202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 392 EAELAQRVA 400
>NP_803172
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 392 EAELAQRVA 400
>XP_005254204
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EAQLAQK 7
           EAQLAQ+
Sbjct: 923 EAQLAQE 929
>XP_005254202
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EAQLAQK 7
           EAQLAQ+
Sbjct: 923 EAQLAQE 929
>XP_005254201
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EAQLAQK 7
           EAQLAQ+
Sbjct: 989 EAQLAQE 995
>XP_006719733
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 336 EAELAQRIA 344
>XP_006719732
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 336 EAELAQRIA 344
>XP_006719731
          Length = 1245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719730
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719729
          Length = 1252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719728
          Length = 1255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719727
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719726
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719725
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719724
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 385 EAELAQRIA 393
>XP_006719723
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719722
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719721
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719720
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719719
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006719718
          Length = 1289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 410 EAELAQRIA 418
>XP_006718787
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718786
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718785
          Length = 1232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718784
          Length = 1242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718783
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718782
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718781
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718780
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_006718779
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 392 EAELAQRVA 400
>XP_006718778
          Length = 1311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 397 EAELAQRVA 405
>XP_005245610
          Length = 1207

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 368 EAELAQRIA 376
>XP_006711654
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
>XP_006711652
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
>XP_006711651
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
>XP_006711650
          Length = 1299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
>XP_006711649
          Length = 1307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 368 EAELAQRIA 376
>XP_006711648
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
>XP_006711647
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAQLAQKSA 9
           EA+LAQ+ A
Sbjct: 369 EAELAQRIA 377
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288   0.0969    0.204 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 254,065
Number of extensions: 392
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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