Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002221                                                              18    1135
NP_068831                                                              18    1135
XP_006721941                                                           18    1135
XP_006721940                                                           18    1135
XP_006721939                                                           18    1135
XP_006721938                                                           18    1135
XP_006721937                                                           18    1135
XP_006721936                                                           18    1135
XP_006721935                                                           18    1135
XP_006721934                                                           18    1135
XP_005257370                                                           18    1135
NP_001895                                                              18    1482
NP_001091680                                                           18    1482
NP_001091679                                                           18    1482
XP_006713048                                                           18    1482
XP_006713047                                                           18    1482
XP_006713046                                                           18    1482
XP_005264943                                                           18    1482
NP_659496                                                              17    3301
XP_006721226                                                           17    3301
XP_006721225                                                           17    3301
XP_006721224                                                           17    3301
NP_001054                                                              17    4312
NP_660328                                                              17    4312
NP_001135886                                                           17    4312
NP_001035738                                                           17    4312
NP_001035737                                                           17    4312
NP_061927                                                              17    4312
XP_006717969                                                           17    4312
XP_005269977                                                           17    4312
XP_006717968                                                           17    4312
XP_006717967                                                           17    4312
XP_006717966                                                           17    4312
XP_006717965                                                           17    4312
NP_055293                                                              17    4312
NP_079239                                                              16    5631
NP_710154                                                              16    5631
XP_005249911                                                           16    5631
XP_005249910                                                           16    5631
NP_036485                                                              16    5631
NP_071397                                                              16    7355
NP_955533                                                              16    7355
NP_115805                                                              16    7355
NP_001127951                                                           16    7355
NP_001269961                                                           16    7355
NP_001269960                                                           16    7355
NP_060573                                                              16    7355
NP_001269962                                                           16    7355
NP_057190                                                              16    7355
NP_878255                                                              16    7355
NP_001244305                                                           16    7355
XP_005267526                                                           16    7355
XP_005270281                                                           16    7355
XP_005270279                                                           16    7355
XP_005270280                                                           16    7355
XP_005244830                                                           16    7355
XP_006710877                                                           16    7355
XP_005244829                                                           16    7355
XP_005271048                                                           16    7355
NP_000833                                                              15    9605
NP_001137303                                                           15    9605
NP_064716                                                              15    9605
NP_056020                                                              15    9605
NP_115565                                                              15    9605
XP_006720028                                                           15    9605
XP_005268363                                                           15    9605
XP_005268362                                                           15    9605
XP_005268358                                                           15    9605
XP_005268360                                                           15    9605
XP_005268357                                                           15    9605
XP_005268356                                                           15    9605
XP_006718893                                                           15    9605
XP_006718892                                                           15    9605
XP_006718891                                                           15    9605
NP_036497                                                              15    9605
>NP_002221
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>NP_068831
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721941
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721940
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721939
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721938
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721937
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721936
          Length = 745

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 436 EALIHAILR 444
>XP_006721935
          Length = 762

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 453 EALIHAILR 461
>XP_006721934
          Length = 783

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 474 EALIHAILR 482
>XP_005257370
          Length = 783

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EAL+H +LR
Sbjct: 474 EALIHAILR 482
>NP_001895
          Length = 781

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 445 EALVRTVLR 453
>NP_001091680
          Length = 781

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 445 EALVRTVLR 453
>NP_001091679
          Length = 781

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 445 EALVRTVLR 453
>XP_006713048
          Length = 720

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 445 EALVRTVLR 453
>XP_006713047
          Length = 774

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 438 EALVRTVLR 446
>XP_006713046
          Length = 774

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 438 EALVRTVLR 446
>XP_005264943
          Length = 781

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           EALV TVLR
Sbjct: 445 EALVRTVLR 453
>NP_659496
          Length = 1084

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 865 EALIHAVL 872
>XP_006721226
          Length = 756

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 537 EALIHAVL 544
>XP_006721225
          Length = 1057

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 838 EALIHAVL 845
>XP_006721224
          Length = 1084

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 865 EALIHAVL 872
>NP_001054
          Length = 698

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           EA VH +LR
Sbjct: 613 EACVHKILR 621
>NP_660328
          Length = 364

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EALVHTVLR 9
          +  VHTVLR
Sbjct: 90 QGYVHTVLR 98
>NP_001135886
          Length = 141

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EALVHTV 7
           EAL+HTV
Sbjct: 107 EALLHTV 113
>NP_001035738
          Length = 71

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EALVHTV 7
          EAL+HTV
Sbjct: 37 EALLHTV 43
>NP_001035737
          Length = 115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  EALVHTV 7
          EAL+HTV
Sbjct: 81 EALLHTV 87
>NP_061927
          Length = 835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 593 DVLVHAVLR 601
>XP_006717969
          Length = 439

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 128 DVLVHAVLR 136
>XP_005269977
          Length = 555

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 244 DVLVHAVLR 252
>XP_006717968
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 641 DVLVHAVLR 649
>XP_006717967
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 641 DVLVHAVLR 649
>XP_006717966
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 641 DVLVHAVLR 649
>XP_006717965
          Length = 958

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           + LVH VLR
Sbjct: 647 DVLVHAVLR 655
>NP_055293
          Length = 148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EALVHTV 7
           EAL+HTV
Sbjct: 114 EALLHTV 120
>NP_079239
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  EALVHTVL 8
          ++L+HTVL
Sbjct: 66 KSLIHTVL 73
>NP_710154
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EALVHTVLR 9
           E+ +H+VLR
Sbjct: 277 ESAIHSVLR 285
>XP_005249911
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  EALVHTVL 8
          ++L+HTVL
Sbjct: 66 KSLIHTVL 73
>XP_005249910
          Length = 801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  EALVHTVL 8
          ++L+HTVL
Sbjct: 66 KSLIHTVL 73
>NP_036485
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ALVHTVL 8
           AL+HTVL
Sbjct: 156 ALLHTVL 162
>NP_071397
          Length = 1276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EALVHTVLR 9
            EAL HT+ R
Sbjct: 1219 EALKHTLCR 1227
>NP_955533
          Length = 1257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EALVHTVLR 9
            EAL HT+ R
Sbjct: 1219 EALKHTLCR 1227
>NP_115805
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 322 EALLHCVL 329
>NP_001127951
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ALVHTVL 8
           AL+HT++
Sbjct: 169 ALIHTII 175
>NP_001269961
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 219 QALVHDVL 226
>NP_001269960
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 93  QALVHDVL 100
>NP_060573
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ALVHTVL 8
           AL+HT++
Sbjct: 169 ALIHTII 175
>NP_001269962
          Length = 457

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 93  QALVHDVL 100
>NP_057190
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 278 QALVHDVL 285
>NP_878255
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 211 QALVHDVL 218
>NP_001244305
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 186 QALVHDVL 193
>XP_005267526
          Length = 617

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           +ALVH VL
Sbjct: 253 QALVHDVL 260
>XP_005270281
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 322 EALLHCVL 329
>XP_005270279
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 322 EALLHCVL 329
>XP_005270280
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EALVHTVL 8
           EAL+H VL
Sbjct: 322 EALLHCVL 329
>XP_005244830
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EALVHTVLR 9
            EAL HT+ R
Sbjct: 1220 EALKHTLCR 1228
>XP_006710877
          Length = 1276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EALVHTVLR 9
            EAL HT+ R
Sbjct: 1219 EALKHTLCR 1227
>XP_005244829
          Length = 1277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EALVHTVLR 9
            EAL HT+ R
Sbjct: 1220 EALKHTLCR 1228
>XP_005271048
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   ALVHTVL 8
           AL+HT++
Sbjct: 169 ALIHTII 175
>NP_000833
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EALVHTVLR 9
          EA++HT+ R
Sbjct: 70 EAMLHTLER 78
>NP_001137303
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EALVHTVLR 9
          EA++HT+ R
Sbjct: 70 EAMLHTLER 78
>NP_064716
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EALVHTVLR 9
           EAL H V+R
Sbjct: 159 EALGHQVIR 167
>NP_056020
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>NP_115565
          Length = 1191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_006720028
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268363
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268362
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268358
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268360
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268357
          Length = 1171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_005268356
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   EALVHTVLR 9
           +AL++TVL+
Sbjct: 307 KALINTVLK 315
>XP_006718893
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EALVHTVLR 9
          EA++HT+ R
Sbjct: 70 EAMLHTLER 78
>XP_006718892
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EALVHTVLR 9
          EA++HT+ R
Sbjct: 70 EAMLHTLER 78
>XP_006718891
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EALVHTVLR 9
          EA++HT+ R
Sbjct: 70 EAMLHTLER 78
>NP_036497
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   ALVHTVL 8
           ALVH VL
Sbjct: 156 ALVHVVL 162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.136    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,123
Number of extensions: 599
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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