Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     390
NP_653080                                                              20     390
XP_005267292                                                           20     390
XP_005267291                                                           20     390
XP_005267290                                                           20     390
NP_055178                                                              16    5631
NP_001264984                                                           16    5631
XP_005266395                                                           16    5631
XP_005272291                                                           16    5631
NP_001009992                                                           16    7355
NP_001123616                                                           16    7355
NP_112593                                                              16    7355
NP_006023                                                              16    7355
NP_775866                                                              16    7355
NP_001267487                                                           16    7355
NP_001020774                                                           16    7355
NP_001640                                                              16    7355
NP_066548                                                              16    7355
NP_000440                                                              16    7355
NP_001157738                                                           16    7355
XP_005274557                                                           16    7355
XP_005258418                                                           16    7355
XP_006722617                                                           16    7355
XP_005258415                                                           16    7355
XP_005258414                                                           16    7355
XP_005268273                                                           16    7355
XP_005245463                                                           16    7355
XP_005245462                                                           16    7355
NP_071342                                                              15    9605
NP_055068                                                              15    9605
NP_001094282                                                           15    9605
NP_001156750                                                           15    9605
NP_277025                                                              15    9605
NP_001278274                                                           15    9605
NP_277024                                                              15    9605
NP_277022                                                              15    9605
NP_001778                                                              15    9605
NP_277021                                                              15    9605
NP_001156751                                                           15    9605
NP_001257449                                                           15    9605
NP_055807                                                              15    9605
NP_849188                                                              15    9605
NP_061863                                                              15    9605
NP_076916                                                              15    9605
NP_277071                                                              15    9605
NP_001160006                                                           15    9605
NP_001160005                                                           15    9605
NP_001017924                                                           15    9605
NP_001271152                                                           15    9605
XP_006724826                                                           15    9605
XP_005267488                                                           15    9605
XP_005267487                                                           15    9605
XP_005248604                                                           15    9605
XP_005248602                                                           15    9605
XP_006711133                                                           15    9605
XP_006711131                                                           15    9605
XP_006711129                                                           15    9605
XP_006711128                                                           15    9605
XP_006711127                                                           15    9605
XP_006711126                                                           15    9605
XP_006711125                                                           15    9605
NP_001136021                                                           15    9605
NP_077726                                                              15    9605
NP_659477                                                              15    9605
>NP_005091
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EAEKGATSD 9
           EAE+GATSD
Sbjct: 591 EAEEGATSD 599
>NP_653080
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EAEKGATSD 9
           EAE+GATSD
Sbjct: 493 EAEEGATSD 501
>XP_005267292
          Length = 1677

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EAEKGATSD 9
           EAE+GATSD
Sbjct: 486 EAEEGATSD 494
>XP_005267291
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EAEKGATSD 9
           EAE+GATSD
Sbjct: 493 EAEEGATSD 501
>XP_005267290
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   EAEKGATSD 9
           EAE+GATSD
Sbjct: 591 EAEEGATSD 599
>NP_055178
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KGATSD 9
           KGATSD
Sbjct: 434 KGATSD 439
>NP_001264984
          Length = 4432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KGATSD 9
           KGATSD
Sbjct: 287 KGATSD 292
>XP_005266395
          Length = 4588

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   KGATSD 9
           KGATSD
Sbjct: 434 KGATSD 439
>XP_005272291
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   EAEKGAT 7
           EAEKGA+
Sbjct: 511 EAEKGAS 517
>NP_001009992
          Length = 568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAEKGATSD 9
          EAEK  T+D
Sbjct: 42 EAEKEGTAD 50
>NP_001123616
          Length = 1303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           E E+G T+D
Sbjct: 507 EEERGVTTD 515
>NP_112593
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A KGATS+
Sbjct: 123 DAIKGATSE 131
>NP_006023
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EAEKGATS 8
           +AE GATS
Sbjct: 93  DAEDGATS 100
>NP_775866
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EKGATSD 9
           EKG+T+D
Sbjct: 709 EKGSTAD 715
>NP_001267487
          Length = 612

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EAEKGATS 8
           +AE GATS
Sbjct: 148 DAEDGATS 155
>NP_001020774
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EAEKGA 6
           EAEKGA
Sbjct: 523 EAEKGA 528
>NP_001640
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AEKGATSD 9
           AEK  TSD
Sbjct: 858 AEKAGTSD 865
>NP_066548
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           E E+G T+D
Sbjct: 507 EEERGVTTD 515
>NP_000440
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EAEKGA 6
           EAEKGA
Sbjct: 523 EAEKGA 528
>NP_001157738
          Length = 1139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           E E+G T+D
Sbjct: 390 EEERGVTTD 398
>XP_005274557
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AEKGATSD 9
           AEK  TSD
Sbjct: 858 AEKAGTSD 865
>XP_005258418
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  EAEKGATSD 9
          +A KGATS+
Sbjct: 84 DAIKGATSE 92
>XP_006722617
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A KGATS+
Sbjct: 195 DAIKGATSE 203
>XP_005258415
          Length = 563

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A KGATS+
Sbjct: 220 DAIKGATSE 228
>XP_005258414
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A KGATS+
Sbjct: 221 DAIKGATSE 229
>XP_005268273
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EAEKGATS 8
           +AE GATS
Sbjct: 93  DAEDGATS 100
>XP_005245463
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EAEKGA 6
           EAEKGA
Sbjct: 523 EAEKGA 528
>XP_005245462
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   EAEKGA 6
           EAEKGA
Sbjct: 523 EAEKGA 528
>NP_071342
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A +GA+SD
Sbjct: 144 QASEGASSD 152
>NP_055068
          Length = 2725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EA+ G+T D
Sbjct: 171 EAQAGSTQD 179
>NP_001094282
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           +A +GA+SD
Sbjct: 144 QASEGASSD 152
>NP_001156750
          Length = 2732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EA+ G+T D
Sbjct: 171 EAQAGSTQD 179
>NP_277025
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EAEKGATSD 9
          E E+G+TS+
Sbjct: 83 EEEEGSTSE 91
>NP_001278274
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 290 EEEEGSTSE 298
>NP_277024
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 266 EEEEGSTSE 274
>NP_277022
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EAEKGATSD 9
          E E+G+TS+
Sbjct: 44 EEEEGSTSE 52
>NP_001778
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 313 EEEEGSTSE 321
>NP_277021
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 300 EEEEGSTSE 308
>NP_001156751
          Length = 2731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EA+ G+T D
Sbjct: 171 EAQAGSTQD 179
>NP_001257449
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EAEKGATS 8
           E  KGATS
Sbjct: 94  EENKGATS 101
>NP_055807
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EAEKGATS 8
           E  KGATS
Sbjct: 94  EENKGATS 101
>NP_849188
          Length = 2400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AEKGATSD 9
           +E+GA+SD
Sbjct: 527 SEEGASSD 534
>NP_061863
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EAEKGATS 8
           EAE+GA S
Sbjct: 322 EAEEGAES 329
>NP_076916
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 298 EEEEGSTSE 306
>NP_277071
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 288 EEEEGSTSE 296
>NP_001160006
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAEKGATSD 9
          EAE G +SD
Sbjct: 81 EAEGGESSD 89
>NP_001160005
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 210 EAEGGESSD 218
>NP_001017924
          Length = 550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   EAEKGATSD 9
           + EKG T D
Sbjct: 540 DKEKGGTED 548
>NP_001271152
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   EAEKGATSD 9
           + EKG T D
Sbjct: 550 DKEKGGTED 558
>XP_006724826
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   EAEKGATS 8
           EAE+GA S
Sbjct: 372 EAEEGAES 379
>XP_005267488
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EAEKGATS 8
           E  KGATS
Sbjct: 94  EENKGATS 101
>XP_005267487
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   EAEKGATS 8
           E  KGATS
Sbjct: 94  EENKGATS 101
>XP_005248604
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 172 EAEGGESSD 180
>XP_005248602
          Length = 700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 206 EAEGGESSD 214
>XP_006711133
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 300 EEEEGSTSE 308
>XP_006711131
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 256 EEEEGSTSE 264
>XP_006711129
          Length = 781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 299 EEEEGSTSE 307
>XP_006711128
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 303 EEEEGSTSE 311
>XP_006711127
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 309 EEEEGSTSE 317
>XP_006711126
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 313 EEEEGSTSE 321
>XP_006711125
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAEKGATSD 9
           E E+G+TS+
Sbjct: 313 EEEEGSTSE 321
>NP_001136021
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 196 EAEGGESSD 204
>NP_077726
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 230 EAEGGESSD 238
>NP_659477
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAEKGATSD 9
           EAE G +SD
Sbjct: 159 EAEVGESSD 167
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.278    0.103    0.242 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 546,621
Number of extensions: 1254
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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