Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     509
XP_006716142                                                           20     509
XP_005250088                                                           20     509
XP_006716141                                                           20     509
XP_005250085                                                           20     509
XP_006716140                                                           20     509
XP_005250084                                                           20     509
XP_005250083                                                           20     509
XP_005250082                                                           20     509
NP_075054                                                              17    3301
NP_000897                                                              17    4312
NP_001166140                                                           17    4312
NP_001166139                                                           17    4312
NP_001166141                                                           17    4312
NP_078982                                                              17    4312
XP_005255636                                                           17    4312
XP_005245275                                                           17    4312
XP_006711406                                                           17    4312
XP_006711405                                                           17    4312
NP_004405                                                              16    5631
XP_005260986                                                           16    5631
NP_055246                                                              16    7355
NP_116326                                                              16    7355
XP_006717829                                                           16    7355
XP_006717828                                                           16    7355
NP_000374                                                              15    9605
NP_002365                                                              15    9605
NP_005583                                                              15    9605
NP_001159752                                                           15    9605
NP_001159753                                                           15    9605
NP_073597                                                              15    9605
NP_001258097                                                           15    9605
NP_001158058                                                           15    9605
XP_006726895                                                           15    9605
XP_006726573                                                           15    9605
XP_006724469                                                           15    9605
XP_006723672                                                           15    9605
XP_005260863                                                           15    9605
XP_005260862                                                           15    9605
XP_005260861                                                           15    9605
XP_005268276                                                           15    9605
XP_006717415                                                           15    9605
XP_005252053                                                           15    9605
XP_005252052                                                           15    9605
XP_005252051                                                           15    9605
XP_005246623                                                           15    9605
XP_005246622                                                           15    9605
XP_005246621                                                           15    9605
XP_005246620                                                           15    9605
XP_005246619                                                           15    9605
XP_005246618                                                           15    9605
XP_005246617                                                           15    9605
XP_005246616                                                           15    9605
XP_006712596                                                           15    9605
XP_005246615                                                           15    9605
XP_005246614                                                           15    9605
XP_006712595                                                           15    9605
XP_006712594                                                           15    9605
XP_006712593                                                           15    9605
XP_005246613                                                           15    9605
XP_005246612                                                           15    9605
XP_006712592                                                           15    9605
XP_005246611                                                           15    9605
XP_006711681                                                           15    9605
XP_006711680                                                           15    9605
XP_005245637                                                           15    9605
XP_006710180                                                           15    9605
XP_006710285                                                           15    9605
NP_004265                                                              15    9605
>NP_733751
          Length = 4911

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4314 EAAQVEAKP 4322
>XP_006716142
          Length = 4927

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4330 EAAQVEAKP 4338
>XP_005250088
          Length = 4928

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4331 EAAQVEAKP 4339
>XP_006716141
          Length = 4959

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4362 EAAQVEAKP 4370
>XP_005250085
          Length = 4979

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4386 EAAQVEAKP 4394
>XP_006716140
          Length = 4982

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4385 EAAQVEAKP 4393
>XP_005250084
          Length = 4982

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4385 EAAQVEAKP 4393
>XP_005250083
          Length = 4982

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4385 EAAQVEAKP 4393
>XP_005250082
          Length = 4983

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    EAAQVKAKP 9
            EAAQV+AKP
Sbjct: 4386 EAAQVEAKP 4394
>NP_075054
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EAAQVKAK 8
           +AAQVKAK
Sbjct: 314 KAAQVKAK 321

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   EAAQVKAK 8
           +AAQVKAK
Sbjct: 325 KAAQVKAK 332
>NP_000897
          Length = 1061

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AQVKAKP 9
          AQVKA+P
Sbjct: 64 AQVKARP 70
>NP_001166140
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAAQVKAKP 9
          E A+VK KP
Sbjct: 75 EVAEVKPKP 83
>NP_001166139
          Length = 619

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAAQVKAKP 9
          E A+VK KP
Sbjct: 52 EVAEVKPKP 60
>NP_001166141
          Length = 619

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAAQVKAKP 9
          E A+VK KP
Sbjct: 52 EVAEVKPKP 60
>NP_078982
          Length = 619

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  EAAQVKAKP 9
          E A+VK KP
Sbjct: 52 EVAEVKPKP 60
>XP_005255636
          Length = 737

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           E A+VK KP
Sbjct: 170 EVAEVKPKP 178
>XP_005245275
          Length = 1035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AQVKAKP 9
          AQVKA+P
Sbjct: 64 AQVKARP 70
>XP_006711406
          Length = 1036

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AQVKAKP 9
          AQVKA+P
Sbjct: 64 AQVKARP 70
>XP_006711405
          Length = 1062

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  AQVKAKP 9
          AQVKA+P
Sbjct: 64 AQVKARP 70
>NP_004405
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EAAQVKAKP 9
          EAA+ +A+P
Sbjct: 18 EAAEARARP 26
>XP_005260986
          Length = 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  EAAQVKAKP 9
          EAA+ +A+P
Sbjct: 18 EAAEARARP 26
>NP_055246
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           EAA  +AKP
Sbjct: 341 EAAPTQAKP 349
>NP_116326
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   EAAQVKAKP 9
           EAA ++A+P
Sbjct: 123 EAASLRARP 131
>XP_006717829
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           EAA  +AKP
Sbjct: 341 EAAPTQAKP 349
>XP_006717828
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           EAA  +AKP
Sbjct: 341 EAAPTQAKP 349
>NP_000374
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   AQVKAKP 9
           +Q+KAKP
Sbjct: 156 SQLKAKP 162
>NP_002365
          Length = 1827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1335 EAAEAQAEP 1343
>NP_005583
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>NP_001159752
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>NP_001159753
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>NP_073597
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>NP_001258097
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>NP_001158058
          Length = 3708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    EAAQVKAKP 9
            EAA  K KP
Sbjct: 2480 EAAGAKGKP 2488
>XP_006726895
          Length = 2288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           +AAQ  AKP
Sbjct: 453 DAAQAIAKP 461
>XP_006726573
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  EAAQVKAKP 9
          EAAQ  A P
Sbjct: 49 EAAQAAASP 57
>XP_006724469
          Length = 2373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           +AAQ  AKP
Sbjct: 486 DAAQAIAKP 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    EAAQVKAKP 9
            +AAQ  AKP
Sbjct: 2062 DAAQAIAKP 2070
>XP_006723672
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>XP_005260863
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>XP_005260862
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>XP_005260861
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  AAQVKAK 8
          AAQ+KAK
Sbjct: 62 AAQLKAK 68
>XP_005268276
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AAQVKAKP 9
           ++QVK KP
Sbjct: 245 SSQVKTKP 252
>XP_006717415
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  EAAQVKAKP 9
          EAAQ  A P
Sbjct: 49 EAAQAAASP 57
>XP_005252053
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>XP_005252052
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>XP_005252051
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   AAQVKAKP 9
           A QVK KP
Sbjct: 114 ALQVKMKP 121
>XP_005246623
          Length = 1757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1177 EAAEAQAEP 1185
>XP_005246622
          Length = 1757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1177 EAAEAQAEP 1185
>XP_005246621
          Length = 1823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1331 EAAEAQAEP 1339
>XP_005246620
          Length = 1827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1335 EAAEAQAEP 1343
>XP_005246619
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1258 EAAEAQAEP 1266
>XP_005246618
          Length = 1911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1331 EAAEAQAEP 1339
>XP_005246617
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1334 EAAEAQAEP 1342
>XP_005246616
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1335 EAAEAQAEP 1343
>XP_006712596
          Length = 1939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_005246615
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_005246614
          Length = 1966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_006712595
          Length = 1996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1416 EAAEAQAEP 1424
>XP_006712594
          Length = 1996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_006712593
          Length = 1996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_005246613
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_005246612
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_006712592
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_005246611
          Length = 1997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    EAAQVKAKP 9
            EAA+ +A+P
Sbjct: 1417 EAAEAQAEP 1425
>XP_006711681
          Length = 3448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    EAAQVKAKP 9
            EAA  K KP
Sbjct: 2480 EAAGAKGKP 2488
>XP_006711680
          Length = 3617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    EAAQVKAKP 9
            EAA  K KP
Sbjct: 2389 EAAGAKGKP 2397
>XP_005245637
          Length = 3683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    EAAQVKAKP 9
            EAA  K KP
Sbjct: 2480 EAAGAKGKP 2488
>XP_006710180
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   EAAQVKAKP 9
           +AAQ  AKP
Sbjct: 402 DAAQAIAKP 410
>XP_006710285
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  EAAQVKAKP 9
          EAAQ  A P
Sbjct: 49 EAAQAAASP 57
>NP_004265
          Length = 2319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AAQVKAKP 9
           ++QVK KP
Sbjct: 245 SSQVKTKP 252
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.108    0.267 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 357,014
Number of extensions: 569
Number of successful extensions: 71
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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