Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001135757                                                           18    1935
NP_001017                                                              18    1935
NP_001135756                                                           18    1935
NP_148982                                                              18    1935
NP_001135755                                                           18    1935
NP_001135754                                                           18    1935
XP_006718001                                                           18    1935
NP_665804                                                              17    3301
NP_783864                                                              17    4312
XP_005262701                                                           17    4312
NP_542198                                                              17    4312
NP_694985                                                              16    5631
NP_006738                                                              16    5631
XP_005274246                                                           16    5631
NP_055733                                                              16    7355
NP_002903                                                              16    7355
NP_060356                                                              16    7355
NP_775853                                                              16    7355
XP_006720498                                                           16    7355
XP_005267148                                                           16    7355
XP_005267147                                                           16    7355
XP_006715606                                                           16    7355
XP_005265319                                                           16    7355
XP_005265318                                                           16    7355
NP_004106                                                              16    7355
NP_060469                                                              16    7355
NP_783328                                                              15    9605
NP_715640                                                              15    9605
NP_060209                                                              15    9605
NP_001273301                                                           15    9605
NP_057569                                                              15    9605
NP_001273300                                                           15    9605
NP_072046                                                              15    9605
NP_001277059                                                           15    9605
NP_001277058                                                           15    9605
NP_000261                                                              15    9605
NP_004382                                                              15    9605
NP_004749                                                              15    9605
NP_073605                                                              15    9605
NP_077729                                                              15    9605
NP_001248764                                                           15    9605
NP_919301                                                              15    9605
NP_001230695                                                           15    9605
XP_006722241                                                           15    9605
XP_006722240                                                           15    9605
XP_006722239                                                           15    9605
XP_006722238                                                           15    9605
XP_005257864                                                           15    9605
XP_006722237                                                           15    9605
XP_006722236                                                           15    9605
XP_005264234                                                           15    9605
XP_006712021                                                           15    9605
XP_005264233                                                           15    9605
XP_005264232                                                           15    9605
XP_006710819                                                           15    9605
XP_006710818                                                           15    9605
XP_005271067                                                           15    9605
>NP_001135757
          Length = 289

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_001017
          Length = 133

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_001135756
          Length = 131

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_148982
          Length = 130

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_001135755
          Length = 132

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_001135754
          Length = 131

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>XP_006718001
          Length = 131

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVVRVFGFK 9
          DV+ VFGF+
Sbjct: 53 DVIFVFGFR 61
>NP_665804
          Length = 359

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DVVRVFGFK 9
          D VR+FG K
Sbjct: 80 DYVRLFGIK 88
>NP_783864
          Length = 1044

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           D +RVFG+
Sbjct: 450 DEIRVFGY 457
>XP_005262701
          Length = 1035

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           D +RVFG+
Sbjct: 450 DEIRVFGY 457
>NP_542198
          Length = 829

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  DVVRVFG 7
          DVV+VFG
Sbjct: 81 DVVQVFG 87
>NP_694985
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DVVRVFGFK 9
           DVVR+ GF+
Sbjct: 369 DVVRLKGFE 377
>NP_006738
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DVVRVFGFK 9
           DVVR+ GF+
Sbjct: 369 DVVRLKGFE 377
>XP_005274246
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DVVRVFGFK 9
           DVVR+ GF+
Sbjct: 369 DVVRLKGFE 377
>NP_055733
          Length = 802

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           D+VRV GF
Sbjct: 702 DLVRVGGF 709
>NP_002903
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VVRVFG 7
          VVRVFG
Sbjct: 37 VVRVFG 42
>NP_060356
          Length = 1275

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DVVRVFG 7
           DVVR FG
Sbjct: 96  DVVREFG 102
>NP_775853
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RVFGFK 9
           +VFGFK
Sbjct: 278 KVFGFK 283
>XP_006720498
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           D+VRV GF
Sbjct: 430 DLVRVGGF 437
>XP_005267148
          Length = 2679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VVRVFG 7
          VVRVFG
Sbjct: 37 VVRVFG 42
>XP_005267147
          Length = 2689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VVRVFG 7
          VVRVFG
Sbjct: 37 VVRVFG 42
>XP_006715606
          Length = 3130

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  VVRVFG 7
          VVRVFG
Sbjct: 37 VVRVFG 42
>XP_005265319
          Length = 897

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DVVRVFG 7
           DVVR FG
Sbjct: 96  DVVREFG 102
>XP_005265318
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DVVRVFG 7
           DVVR FG
Sbjct: 96  DVVREFG 102
>NP_004106
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  VRVFGFK 9
          VR+FG K
Sbjct: 51 VRIFGLK 57
>NP_060469
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   DVVRVFGF 8
           DV+R++G+
Sbjct: 117 DVLRLYGY 124
>NP_783328
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 863 EMERVFGF 870
>NP_715640
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 674 EMERVFGF 681
>NP_060209
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 346 DVVALFGLR 354
>NP_001273301
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVVRVFG 7
          DV+ VFG
Sbjct: 68 DVITVFG 74
>NP_057569
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DVVRVFG 7
           DV+ VFG
Sbjct: 126 DVITVFG 132
>NP_001273300
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DVVRVFG 7
           DV+ VFG
Sbjct: 126 DVITVFG 132
>NP_072046
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 863 EMERVFGF 870
>NP_001277059
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 203 DVVALFGLR 211
>NP_001277058
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 324 DVVALFGLR 332
>NP_000261
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   VRVFGF 8
           +RVFGF
Sbjct: 233 LRVFGF 238
>NP_004382
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   VVRVFGFK 9
           V++VFG++
Sbjct: 107 VLKVFGYR 114
>NP_004749
          Length = 1857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1796 DVITVFG 1802
>NP_073605
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VVRVFGFK 9
           +VR FGF+
Sbjct: 952 IVRGFGFQ 959
>NP_077729
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1736 DVITVFG 1742
>NP_001248764
          Length = 1848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1787 DVITVFG 1793
>NP_919301
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   RVFGFK 9
           R FGFK
Sbjct: 493 RAFGFK 498
>NP_001230695
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 346 DVVALFGLR 354
>XP_006722241
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1356 DVITVFG 1362
>XP_006722240
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1356 DVITVFG 1362
>XP_006722239
          Length = 1630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1519 DVITVFG 1525
>XP_006722238
          Length = 1847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1736 DVITVFG 1742
>XP_005257864
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1787 DVITVFG 1793
>XP_006722237
          Length = 1900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1789 DVITVFG 1795
>XP_006722236
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVVRVFG 7
            DV+ VFG
Sbjct: 1796 DVITVFG 1802
>XP_005264234
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 640 EMERVFGF 647
>XP_006712021
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 715 EMERVFGF 722
>XP_005264233
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 863 EMERVFGF 870
>XP_005264232
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DVVRVFGF 8
           ++ RVFGF
Sbjct: 863 EMERVFGF 870
>XP_006710819
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 346 DVVALFGLR 354
>XP_006710818
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 346 DVVALFGLR 354
>XP_005271067
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVVRVFGFK 9
           DVV +FG +
Sbjct: 346 DVVALFGLR 354
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.163    0.496 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 408,394
Number of extensions: 659
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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