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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003669                                                              17    2528
NP_001002878                                                           17    2528
NP_001002879                                                           17    2528
NP_001002877                                                           17    2528
XP_005261856                                                           17    2528
XP_006724410                                                           17    2528
XP_005261855                                                           17    2528
XP_005261854                                                           17    2528
NP_060710                                                              16    7355
NP_001273278                                                           16    7355
NP_848594                                                              16    7355
NP_705691                                                              16    7355
NP_001268227                                                           16    7355
XP_006719330                                                           16    7355
XP_005253911                                                           16    7355
XP_006719329                                                           16    7355
XP_006719328                                                           16    7355
XP_006715119                                                           16    7355
XP_006711493                                                           16    7355
XP_005245363                                                           16    7355
XP_005245362                                                           16    7355
NP_001027392                                                           16    7355
NP_001070650                                                           15    9605
NP_036550                                                              15    9605
NP_000897                                                              15    9605
XP_005257253                                                           15    9605
XP_005257252                                                           15    9605
XP_005245275                                                           15    9605
XP_006711406                                                           15    9605
XP_006711405                                                           15    9605

>NP_003669
          Length = 683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>NP_001002878
          Length = 683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>NP_001002879
          Length = 683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>NP_001002877
          Length = 683

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>XP_005261856
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>XP_006724410
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>XP_005261855
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>XP_005261854
          Length = 694

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VTLKKINR 9
           +TLKK+NR
Sbjct: 96  MTLKKLNR 103



>NP_060710
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVTLKKIN 8
           DVTL+K++
Sbjct: 530 DVTLRKLD 537



>NP_001273278
          Length = 657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVTLKKIN 8
           DVTL+K++
Sbjct: 430 DVTLRKLD 437



>NP_848594
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           T+KKIN+
Sbjct: 194 TIKKINK 200



>NP_705691
          Length = 955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DVTLKK 6
           DVTLKK
Sbjct: 908 DVTLKK 913



>NP_001268227
          Length = 127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  VTLKKIN 8
          VTL+KIN
Sbjct: 73 VTLEKIN 79



>XP_006719330
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           T+KKIN+
Sbjct: 194 TIKKINK 200



>XP_005253911
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           T+KKIN+
Sbjct: 194 TIKKINK 200



>XP_006719329
          Length = 506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           T+KKIN+
Sbjct: 194 TIKKINK 200



>XP_006719328
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           T+KKIN+
Sbjct: 194 TIKKINK 200



>XP_006715119
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DVTLKK 6
           DVTLKK
Sbjct: 908 DVTLKK 913



>XP_006711493
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVTLKKIN 8
           DVTL+K++
Sbjct: 446 DVTLRKLD 453



>XP_005245363
          Length = 723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVTLKKIN 8
           DVTL+K++
Sbjct: 496 DVTLRKLD 503



>XP_005245362
          Length = 773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVTLKKIN 8
           DVTL+K++
Sbjct: 546 DVTLRKLD 553



>NP_001027392
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TLKKINR 9
           TLKK+N+
Sbjct: 581 TLKKLNK 587



>NP_001070650
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVTLKKINR 9
           + TLK INR
Sbjct: 397 EFTLKLINR 405



>NP_036550
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVTLKKINR 9
           + TLK INR
Sbjct: 373 EFTLKLINR 381



>NP_000897
          Length = 1061

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VTLKKINR 9
           +TL+K NR
Sbjct: 799 LTLRKFNR 806



>XP_005257253
          Length = 492

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVTLKKINR 9
           + TLK INR
Sbjct: 373 EFTLKLINR 381



>XP_005257252
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVTLKKINR 9
           + TLK INR
Sbjct: 397 EFTLKLINR 405



>XP_005245275
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VTLKKINR 9
           +TL+K NR
Sbjct: 773 LTLRKFNR 780



>XP_006711406
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VTLKKINR 9
           +TL+K NR
Sbjct: 774 LTLRKFNR 781



>XP_006711405
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VTLKKINR 9
           +TL+K NR
Sbjct: 800 LTLRKFNR 807



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.136    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 381,889
Number of extensions: 602
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)