Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
NP_569707                                                              17    2528
XP_005271139                                                           17    2528
XP_006710863                                                           17    2528
XP_006710861                                                           17    2528
XP_005271138                                                           17    2528
XP_006710859                                                           17    2528
NP_940892                                                              17    3301
NP_001191814                                                           17    3301
NP_001191813                                                           17    3301
NP_001191815                                                           17    3301
NP_001191812                                                           17    3301
NP_001129628                                                           16    7355
NP_001138600                                                           16    7355
NP_002009                                                              16    7355
NP_001243193                                                           16    7355
NP_055725                                                              16    7355
NP_001243194                                                           16    7355
XP_005256615                                                           16    7355
XP_005256613                                                           16    7355
XP_005256612                                                           16    7355
XP_006715439                                                           16    7355
NP_060383                                                              15    9605
NP_938020                                                              15    9605
XP_006724542                                                           15    9605
XP_005274533                                                           15    9605
XP_005274532                                                           15    9605
XP_006724541                                                           15    9605
XP_005274531                                                           15    9605
XP_006724540                                                           15    9605
XP_005274530                                                           15    9605
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1737 VSLAEAQQ 1744
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1737 VSLAEAQQ 1744
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1693 VSLAEAQQ 1700
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           VSLAEAQQ
Sbjct: 744 VSLAEAQQ 751
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1693 VSLAEAQQ 1700
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1802 VSLAEAQQ 1809
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1736 VSLAEAQQ 1743
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1737 VSLAEAQQ 1744
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1740 VSLAEAQQ 1747
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1790 VSLAEAQQ 1797
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1802 VSLAEAQQ 1809
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1803 VSLAEAQQ 1810
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1899 VSLAEAQQ 1906
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAEAQQ
Sbjct: 1900 VSLAEAQQ 1907
>NP_569707
          Length = 1898

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 764 DVMLAEAQE 772
>XP_005271139
          Length = 1796

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 662 DVMLAEAQE 670
>XP_006710863
          Length = 1811

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 666 DVMLAEAQE 674
>XP_006710861
          Length = 1902

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 768 DVMLAEAQE 776
>XP_005271138
          Length = 1909

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 764 DVMLAEAQE 772
>XP_006710859
          Length = 1913

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   DVSLAEAQQ 9
           DV LAEAQ+
Sbjct: 768 DVMLAEAQE 776
>NP_940892
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   DVSLAEAQ 8
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191814
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   DVSLAEAQ 8
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191813
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   DVSLAEAQ 8
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191815
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   DVSLAEAQ 8
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001191812
          Length = 212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   DVSLAEAQ 8
           +VSLAEAQ
Sbjct: 140 EVSLAEAQ 147
>NP_001129628
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SL EAQ
Sbjct: 425 DLSLTEAQ 432
>NP_001138600
          Length = 1911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAE+Q+
Sbjct: 1645 VSLAESQE 1652
>NP_002009
          Length = 1269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 888 MSLAEAEQ 895
>NP_001243193
          Length = 1258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 877 MSLAEAEQ 884
>NP_055725
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SL EAQ
Sbjct: 425 DLSLTEAQ 432
>NP_001243194
          Length = 1214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 833 MSLAEAEQ 840
>XP_005256615
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 887 MSLAEAEQ 894
>XP_005256613
          Length = 1295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 887 MSLAEAEQ 894
>XP_005256612
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VSLAEAQQ 9
           +SLAEA+Q
Sbjct: 888 MSLAEAEQ 895
>XP_006715439
          Length = 1911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    VSLAEAQQ 9
            VSLAE+Q+
Sbjct: 1645 VSLAESQE 1652
>NP_060383
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  SLAEAQQ 9
          +LAEAQQ
Sbjct: 70 NLAEAQQ 76
>NP_938020
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_006724542
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274533
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274532
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_006724541
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274531
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 505 DMSLAELQ 512
>XP_006724540
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
>XP_005274530
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DVSLAEAQ 8
           D+SLAE Q
Sbjct: 525 DMSLAELQ 532
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.109    0.246 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,945
Number of extensions: 437
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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