Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           19     869
NP_000242                                                              19     869
XP_005264389                                                           19     869
NP_057726                                                              17    4312
XP_005254495                                                           17    4312
NP_001018098                                                           16    7355
NP_060154                                                              16    7355
NP_060550                                                              16    7355
NP_065872                                                              16    7355
NP_001078823                                                           16    7355
NP_071934                                                              16    7355
NP_115516                                                              16    7355
NP_001026884                                                           16    7355
NP_078933                                                              16    7355
NP_872378                                                              16    7355
XP_006724755                                                           16    7355
XP_005262247                                                           16    7355
XP_006723212                                                           16    7355
XP_005268062                                                           16    7355
XP_005268061                                                           16    7355
NP_112486                                                              16    7355
NP_056003                                                              15    9605
NP_060493                                                              15    9605
XP_006717796                                                           15    9605
XP_006717795                                                           15    9605
XP_006713751                                                           15    9605
XP_005247655                                                           15    9605
XP_005247654                                                           15    9605
>NP_001245210
          Length = 868

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           DVL QLDAV
Sbjct: 531 DVLAQLDAV 539
>NP_000242
          Length = 934

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           DVL QLDAV
Sbjct: 597 DVLAQLDAV 605
>XP_005264389
          Length = 921

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           DVL QLDAV
Sbjct: 597 DVLAQLDAV 605
>NP_057726
          Length = 3674

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DVLVQLDAV 9
            DVL+QL+A+
Sbjct: 1018 DVLLQLEAL 1026
>XP_005254495
          Length = 3694

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    DVLVQLDAV 9
            DVL+QL+A+
Sbjct: 1038 DVLLQLEAL 1046
>NP_001018098
          Length = 3628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VLVQLDA 8
            VLVQ+DA
Sbjct: 2526 VLVQIDA 2532
>NP_060154
          Length = 3710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VLVQLDA 8
            VLVQ+DA
Sbjct: 2483 VLVQIDA 2489
>NP_060550
          Length = 3585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VLVQLDA 8
            VLVQ+DA
Sbjct: 2483 VLVQIDA 2489
>NP_065872
          Length = 3753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VLVQLDA 8
            VLVQ+DA
Sbjct: 2526 VLVQIDA 2532
>NP_001078823
          Length = 900

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVLVQLDAV 9
           D+L Q DA+
Sbjct: 202 DLLAQFDAI 210
>NP_071934
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVLVQLDA 8
           D+L+QL+A
Sbjct: 240 DLLIQLEA 247
>NP_115516
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DVLVQLDAV 9
          DVL+QL+ +
Sbjct: 76 DVLLQLEGI 84
>NP_001026884
          Length = 1240

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVLVQLDA 8
           D+L+QL+A
Sbjct: 240 DLLIQLEA 247
>NP_078933
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVLVQLDAV 9
           D+L Q DA+
Sbjct: 202 DLLAQFDAI 210
>NP_872378
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           +VLV LD+V
Sbjct: 123 EVLVSLDSV 131
>XP_006724755
          Length = 532

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVLVQLDAV 9
           D+L Q DA+
Sbjct: 202 DLLAQFDAI 210
>XP_005262247
          Length = 845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DVLVQLDAV 9
           D+L Q DA+
Sbjct: 110 DLLAQFDAI 118
>XP_006723212
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           +VLV LD+V
Sbjct: 163 EVLVSLDSV 171
>XP_005268062
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVLVQLDA 8
           D+L+QL+A
Sbjct: 272 DLLIQLEA 279
>XP_005268061
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   DVLVQLDA 8
           D+L+QL+A
Sbjct: 272 DLLIQLEA 279
>NP_112486
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           D+++QLD V
Sbjct: 153 DIIMQLDDV 161
>NP_056003
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           D+L+Q+D +
Sbjct: 709 DILLQMDFI 717
>NP_060493
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DVLVQLDA 8
            DVL Q+D+
Sbjct: 1252 DVLTQIDS 1259
>XP_006717796
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           D+L+Q+D +
Sbjct: 286 DILLQMDFI 294
>XP_006717795
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   DVLVQLDAV 9
           D+L+Q+D +
Sbjct: 775 DILLQMDFI 783
>XP_006713751
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DVLVQLDA 8
            DVL Q+D+
Sbjct: 1253 DVLTQIDS 1260
>XP_005247655
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DVLVQLDA 8
            DVL Q+D+
Sbjct: 1253 DVLTQIDS 1260
>XP_005247654
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DVLVQLDA 8
            DVL Q+D+
Sbjct: 1253 DVLTQIDS 1260
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.144    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 347,551
Number of extensions: 485
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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