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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_001274691                                                           16    5631
NP_001274690                                                           16    5631
NP_004204                                                              16    5631
XP_005255050                                                           16    5631
XP_005255048                                                           16    5631
XP_005255046                                                           16    5631
NP_002262                                                              16    7355
NP_001010852                                                           16    7355
NP_775790                                                              16    7355
NP_056017                                                              16    7355
XP_005255265                                                           16    7355
XP_005255264                                                           16    7355
XP_005255263                                                           16    7355
XP_005255261                                                           16    7355
XP_006721088                                                           16    7355
XP_005255260                                                           16    7355
XP_005255259                                                           16    7355
XP_005255258                                                           16    7355
XP_005254110                                                           16    7355
XP_005254109                                                           16    7355
XP_005254106                                                           16    7355
XP_005251234                                                           16    7355
XP_005251233                                                           16    7355
NP_524146                                                              15    9605
NP_524144                                                              15    9605
NP_775829                                                              15    9605
NP_001361                                                              15    9605
XP_005257331                                                           15    9605
XP_005248968                                                           15    9605
XP_006712019                                                           15    9605

>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLRAIFTS 9
            DVLR IFTS
Sbjct: 2937 DVLRGIFTS 2945



>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DVLRAIFTS 9
            DVLR IFTS
Sbjct: 2937 DVLRGIFTS 2945



>NP_001274691
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 569 VLRALFT 575



>NP_001274690
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 403 VLRALFT 409



>NP_004204
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 569 VLRALFT 575



>XP_005255050
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 543 VLRALFT 549



>XP_005255048
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 569 VLRALFT 575



>XP_005255046
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VLRAIFT 8
           VLRA+FT
Sbjct: 569 VLRALFT 575



>NP_002262
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           D+L +IF+S
Sbjct: 862 DILHSIFSS 870



>NP_001010852
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+LRAI  S
Sbjct: 135 DILRAILLS 143



>NP_775790
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+LRAI  S
Sbjct: 157 DILRAILLS 165



>NP_056017
          Length = 1618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1131 DILEAIFYS 1139



>XP_005255265
          Length = 1211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+L AIF S
Sbjct: 724 DILEAIFYS 732



>XP_005255264
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+L AIF S
Sbjct: 757 DILEAIFYS 765



>XP_005255263
          Length = 1248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1192 DILEAIFYS 1200



>XP_005255261
          Length = 1280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1192 DILEAIFYS 1200



>XP_006721088
          Length = 1592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1105 DILEAIFYS 1113



>XP_005255260
          Length = 1636

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1149 DILEAIFYS 1157



>XP_005255259
          Length = 1661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1174 DILEAIFYS 1182



>XP_005255258
          Length = 1679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    DVLRAIFTS 9
            D+L AIF S
Sbjct: 1192 DILEAIFYS 1200



>XP_005254110
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           D+L +IF+S
Sbjct: 862 DILHSIFSS 870



>XP_005254109
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           D+L +IF+S
Sbjct: 862 DILHSIFSS 870



>XP_005254106
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           D+L +IF+S
Sbjct: 862 DILHSIFSS 870



>XP_005251234
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+LRAI  S
Sbjct: 157 DILRAILLS 165



>XP_005251233
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLRAIFTS 9
           D+LRAI  S
Sbjct: 157 DILRAILLS 165



>NP_524146
          Length = 150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVLRAIFTS 9
          DVLRA+ T+
Sbjct: 33 DVLRALGTN 41



>NP_524144
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DVLRAIFTS 9
          DVLRA+ T+
Sbjct: 77 DVLRALGTN 85



>NP_775829
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           DV+R IF++
Sbjct: 145 DVVRVIFSN 153



>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VLRAIFTS 9
            +LR +FTS
Sbjct: 3239 ILRMLFTS 3246



>XP_005257331
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LRAIFTS 9
          +RA+FTS
Sbjct: 10 IRALFTS 16



>XP_005248968
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLRAIFTS 9
           DV+R IF++
Sbjct: 145 DVVRVIFSN 153



>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VLRAIFTS 9
            +LR +FTS
Sbjct: 3239 ILRMLFTS 3246



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.143    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 326,162
Number of extensions: 554
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)