Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     665
NP_005913                                                              19     665
XP_005267046                                                           19     665
XP_005267045                                                           19     665
NP_001017924                                                           16    5631
NP_001271152                                                           16    5631
NP_001267474                                                           16    7355
NP_443715                                                              16    7355
NP_443711                                                              16    7355
NP_078865                                                              16    7355
XP_006721011                                                           16    7355
XP_006721010                                                           16    7355
XP_006718815                                                           16    7355
XP_006713758                                                           16    7355
XP_006713756                                                           16    7355
XP_005247664                                                           16    7355
XP_006713754                                                           16    7355
XP_006713753                                                           16    7355
XP_005247661                                                           16    7355
XP_006713752                                                           16    7355
XP_005247660                                                           16    7355
NP_055601                                                              16    7355
NP_612355                                                              15    9605
NP_808220                                                              15    9605
NP_055518                                                              15    9605
NP_079150                                                              15    9605
NP_001017390                                                           15    9605
NP_776161                                                              15    9605
NP_001008539                                                           15    9605
NP_001158243                                                           15    9605
NP_003037                                                              15    9605
NP_004809                                                              15    9605
NP_079203                                                              15    9605
NP_940969                                                              15    9605
XP_006726684                                                           15    9605
XP_005276564                                                           15    9605
XP_005276563                                                           15    9605
XP_006726657                                                           15    9605
XP_006725285                                                           15    9605
XP_006722159                                                           15    9605
XP_006719762                                                           15    9605
XP_005273669                                                           15    9605
XP_005273668                                                           15    9605
XP_005273667                                                           15    9605
XP_006716452                                                           15    9605
XP_005273666                                                           15    9605
XP_005265966                                                           15    9605
XP_006714634                                                           15    9605
XP_005271976                                                           15    9605
XP_005276812                                                           15    9605
XP_006713491                                                           15    9605
XP_005276811                                                           15    9605
XP_006713490                                                           15    9605
XP_005276810                                                           15    9605
XP_005276809                                                           15    9605
XP_006713489                                                           15    9605
XP_005276808                                                           15    9605
XP_005263588                                                           15    9605
XP_006710972                                                           15    9605
XP_006710971                                                           15    9605
XP_006710970                                                           15    9605
NP_008993                                                              15    9605
>NP_006715
          Length = 1558

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DVLINAYLL 9
           DVLI+AYLL
Sbjct: 894 DVLIDAYLL 902
>NP_005913
          Length = 1608

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DVLINAYLL 9
           DVLI+AYLL
Sbjct: 894 DVLIDAYLL 902
>XP_005267046
          Length = 1554

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DVLINAYLL 9
           DVLI+AYLL
Sbjct: 894 DVLIDAYLL 902
>XP_005267045
          Length = 1604

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DVLINAYLL 9
           DVLI+AYLL
Sbjct: 894 DVLIDAYLL 902
>NP_001017924
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   VLINAYLL 9
           +L+N+YL+
Sbjct: 223 ILVNSYLI 230
>NP_001271152
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   VLINAYLL 9
           +L+N+YL+
Sbjct: 223 ILVNSYLI 230
>NP_001267474
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DVLINAYL 8
          DV++N Y+
Sbjct: 54 DVIVNRYI 61
>NP_443715
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>NP_443711
          Length = 1292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 255 DVIVNRYI 262
>NP_078865
          Length = 287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           D+L+N Y+
Sbjct: 187 DLLVNVYI 194
>XP_006721011
          Length = 204

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           D+L+N Y+
Sbjct: 97  DLLVNVYI 104
>XP_006721010
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           D+L+N Y+
Sbjct: 187 DLLVNVYI 194
>XP_006718815
          Length = 1057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DVLINAY 7
           DVL+N Y
Sbjct: 149 DVLVNIY 155
>XP_006713758
          Length = 877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>XP_006713756
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DVLINAYL 8
          DV++N Y+
Sbjct: 54 DVIVNRYI 61
>XP_005247664
          Length = 1191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 152 DVIVNRYI 159
>XP_006713754
          Length = 1224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>XP_006713753
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>XP_005247661
          Length = 1242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>XP_006713752
          Length = 1242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>XP_005247660
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DVLINAYL 8
           DV++N Y+
Sbjct: 204 DVIVNRYI 211
>NP_055601
          Length = 2063

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    DVLINAY 7
            DVL+N Y
Sbjct: 1155 DVLVNIY 1161
>NP_612355
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N+Y L
Sbjct: 475 DVLHNSYAL 483
>NP_808220
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVLINAY 7
          D+LIN Y
Sbjct: 40 DLLINTY 46
>NP_055518
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>NP_079150
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLINAYLL 9
           +V +NAY+L
Sbjct: 325 EVQLNAYVL 333
>NP_001017390
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVLINAY 7
          D+LIN Y
Sbjct: 40 DLLINTY 46
>NP_776161
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   DVLINAY 7
           D+L+N Y
Sbjct: 840 DILLNTY 846
>NP_001008539
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 569 ILVNIYLM 576
>NP_001158243
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 609 ILVNIYLM 616
>NP_003037
          Length = 697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 608 ILVNIYLM 615
>NP_004809
          Length = 820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N YL+
Sbjct: 531 DVLENRYLV 539
>NP_079203
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LINAYL 8
           L+NAYL
Sbjct: 742 LVNAYL 747
>NP_940969
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL  AY+L
Sbjct: 107 DVLKEAYML 115
>XP_006726684
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVLINAY 7
          D+LIN Y
Sbjct: 40 DLLINTY 46
>XP_005276564
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVLINAY 7
          D+LIN Y
Sbjct: 40 DLLINTY 46
>XP_005276563
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  DVLINAY 7
          D+LIN Y
Sbjct: 40 DLLINTY 46
>XP_006726657
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N+Y L
Sbjct: 474 DVLQNSYAL 482
>XP_006725285
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N+Y L
Sbjct: 474 DVLQNSYAL 482
>XP_006722159
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LINAYL 8
           L+NAYL
Sbjct: 739 LVNAYL 744
>XP_006719762
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N YL+
Sbjct: 531 DVLENRYLV 539
>XP_005273669
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 569 ILVNIYLM 576
>XP_005273668
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 569 ILVNIYLM 576
>XP_005273667
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 569 ILVNIYLM 576
>XP_006716452
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 587 ILVNIYLM 594
>XP_005273666
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   VLINAYLL 9
           +L+N YL+
Sbjct: 588 ILVNIYLM 595
>XP_005265966
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL  AY+L
Sbjct: 541 DVLKEAYML 549
>XP_006714634
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   DVLINAY 7
           D+L+N Y
Sbjct: 357 DILLNTY 363
>XP_005271976
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   DVLINAY 7
           D+L+N Y
Sbjct: 432 DILLNTY 438
>XP_005276812
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_006713491
          Length = 1425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  VLINAYLL 9
          +L+NAY++
Sbjct: 5  LLVNAYVM 12
>XP_005276811
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_006713490
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_005276810
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_005276809
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_006713489
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_005276808
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  DVLINAYLL 9
          + L+NAY++
Sbjct: 86 NALVNAYVM 94
>XP_005263588
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DVLINAYLL 9
           DVL N+Y L
Sbjct: 475 DVLHNSYAL 483
>XP_006710972
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLINAYLL 9
           +V +NAY+L
Sbjct: 325 EVQLNAYVL 333
>XP_006710971
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLINAYLL 9
           +V +NAY+L
Sbjct: 325 EVQLNAYVL 333
>XP_006710970
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLINAYLL 9
           +V +NAY+L
Sbjct: 325 EVQLNAYVL 333
>NP_008993
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DVLINAYLL 9
           D+L++AY L
Sbjct: 181 DILLSAYPL 189
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.154    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 425,937
Number of extensions: 738
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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