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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              19     665
XP_005248577                                                           19     665
XP_005248576                                                           19     665
NP_001167448                                                           17    4312
NP_060110                                                              17    4312
XP_006715203                                                           17    4312
XP_006715202                                                           17    4312
XP_006715201                                                           17    4312
XP_006715200                                                           17    4312
XP_005249275                                                           17    4312
XP_006715199                                                           17    4312
NP_003592                                                              15    9605
NP_068761                                                              15    9605
NP_001269804                                                           15    9605
NP_001269803                                                           15    9605
NP_003060                                                              15    9605
NP_951008                                                              15    9605
XP_006724845                                                           15    9605
XP_005262519                                                           15    9605
XP_005262518                                                           15    9605
NP_002687                                                              15    9605

>NP_005912
          Length = 1512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DTIIIQQDT 9
            D IIIQQDT
Sbjct: 1215 DIIIIQQDT 1223



>XP_005248577
          Length = 1349

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DTIIIQQDT 9
            D IIIQQDT
Sbjct: 1052 DIIIIQQDT 1060



>XP_005248576
          Length = 1375

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    DTIIIQQDT 9
            D IIIQQDT
Sbjct: 1078 DIIIIQQDT 1086



>NP_001167448
          Length = 1365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>NP_060110
          Length = 1371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_006715203
          Length = 949

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_006715202
          Length = 966

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_006715201
          Length = 1375

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_006715200
          Length = 1419

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_005249275
          Length = 1421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>XP_006715199
          Length = 1425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           DTI + QDT
Sbjct: 183 DTIYLTQDT 191



>NP_003592
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 628 DSIVIQQ 634



>NP_068761
          Length = 1133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           D+IIIQ  T
Sbjct: 737 DSIIIQAST 745



>NP_001269804
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 631 DSIVIQQ 637



>NP_001269803
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 643 DSIVIQQ 649



>NP_003060
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 643 DSIVIQQ 649



>NP_951008
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTIIIQQDT 9
           D+IIIQ  T
Sbjct: 737 DSIIIQAST 745



>XP_006724845
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 631 DSIVIQQ 637



>XP_005262519
          Length = 1048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 643 DSIVIQQ 649



>XP_005262518
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DTIIIQQ 7
           D+I+IQQ
Sbjct: 643 DSIVIQQ 649



>NP_002687
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DTIIIQQD 8
           + I+IQQD
Sbjct: 133 EDIVIQQD 140



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.137    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 416,414
Number of extensions: 637
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)