Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     299
XP_005271621                                                           20     299
XP_006718907                                                           20     299
XP_006718906                                                           20     299
XP_005271619                                                           20     299
XP_005271618                                                           20     299
XP_005276372                                                           17    2528
NP_001180277                                                           17    4312
NP_001180276                                                           17    4312
NP_001124477                                                           17    4312
NP_001180278                                                           17    4312
NP_002388                                                              17    4312
NP_001180279                                                           17    4312
XP_006714688                                                           17    4312
XP_006714687                                                           17    4312
XP_006714686                                                           17    4312
XP_006714685                                                           17    4312
XP_006714684                                                           17    4312
XP_006714683                                                           17    4312
XP_005248568                                                           17    4312
XP_006714682                                                           17    4312
XP_006714681                                                           17    4312
NP_659455                                                              16    5631
NP_001010852                                                           16    5631
NP_075055                                                              16    5631
XP_006722904                                                           16    5631
XP_005260077                                                           16    5631
XP_006718530                                                           16    5631
NP_002175                                                              16    7355
NP_001177910                                                           16    7355
NP_056537                                                              16    7355
NP_065928                                                              16    7355
XP_005256527                                                           16    7355
XP_005252742                                                           16    7355
NP_078850                                                              16    7355
NP_001156909                                                           15    9605
NP_149106                                                              15    9605
NP_001156908                                                           15    9605
NP_001277697                                                           15    9605
NP_001156907                                                           15    9605
NP_001073982                                                           15    9605
NP_001073379                                                           15    9605
NP_001138409                                                           15    9605
NP_005699                                                              15    9605
NP_001107604                                                           15    9605
NP_001269065                                                           15    9605
NP_000631                                                              15    9605
XP_006719974                                                           15    9605
XP_005254074                                                           15    9605
XP_006719697                                                           15    9605
XP_006719696                                                           15    9605
XP_006719695                                                           15    9605
XP_005269238                                                           15    9605
XP_005248831                                                           15    9605
XP_005248830                                                           15    9605
XP_006715361                                                           15    9605
XP_005249448                                                           15    9605
XP_006714482                                                           15    9605
XP_005269338                                                           15    9605
XP_005269337                                                           15    9605
XP_006712762                                                           15    9605
XP_005270607                                                           15    9605
>NP_000042
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    DTEYNLSS 8
            DTEYNLSS
Sbjct: 1226 DTEYNLSS 1233
>XP_005271621
          Length = 2708

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   DTEYNLSS 8
           DTEYNLSS
Sbjct: 878 DTEYNLSS 885
>XP_006718907
          Length = 3050

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    DTEYNLSS 8
            DTEYNLSS
Sbjct: 1220 DTEYNLSS 1227
>XP_006718906
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    DTEYNLSS 8
            DTEYNLSS
Sbjct: 1226 DTEYNLSS 1233
>XP_005271619
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    DTEYNLSS 8
            DTEYNLSS
Sbjct: 1226 DTEYNLSS 1233
>XP_005271618
          Length = 3056

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    DTEYNLSS 8
            DTEYNLSS
Sbjct: 1226 DTEYNLSS 1233
>XP_005276372
          Length = 280

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEYN S
Sbjct: 266 DTEYNFS 272
>NP_001180277
          Length = 417

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 265 TEYSLSSA 272
>NP_001180276
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 331 TEYSLSSA 338
>NP_001124477
          Length = 463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 311 TEYSLSSA 318
>NP_001180278
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 273 TEYSLSSA 280
>NP_002388
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>NP_001180279
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>XP_006714688
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 331 TEYSLSSA 338
>XP_006714687
          Length = 433

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 313 TEYSLSSA 320
>XP_006714686
          Length = 441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>XP_006714685
          Length = 463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 311 TEYSLSSA 318
>XP_006714684
          Length = 465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 313 TEYSLSSA 320
>XP_006714683
          Length = 471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 319 TEYSLSSA 326
>XP_005248568
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>XP_006714682
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>XP_006714681
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TEYNLSSS 9
           TEY+LSS+
Sbjct: 321 TEYSLSSA 328
>NP_659455
          Length = 998

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DTEYNLSSS 9
           D+EYN  +S
Sbjct: 757 DSEYNFENS 765
>NP_001010852
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DTEYNLSS 8
           D+EYN+ S
Sbjct: 273 DSEYNVDS 280
>NP_075055
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTEYNLSSS 9
           D+E+NL+S+
Sbjct: 948 DSEHNLTSN 956
>XP_006722904
          Length = 546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTEYNLSSS 9
           D+E+NL+S+
Sbjct: 483 DSEHNLTSN 491
>XP_005260077
          Length = 1005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTEYNLSSS 9
           D+E+NL+S+
Sbjct: 942 DSEHNLTSN 950
>XP_006718530
          Length = 697

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DTEYNLSSS 9
           D+EYN  +S
Sbjct: 456 DSEYNFENS 464
>NP_002175
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TEYNLSS 8
           TEY LSS
Sbjct: 575 TEYTLSS 581
>NP_001177910
          Length = 857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TEYNLSS 8
           TEY LSS
Sbjct: 514 TEYTLSS 520
>NP_056537
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TEYNLSS 8
          TEY LSS
Sbjct: 52 TEYQLSS 58
>NP_065928
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    EYNLSSS 9
            EYNLS S
Sbjct: 2722 EYNLSPS 2728
>XP_005256527
          Length = 4427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    EYNLSSS 9
            EYNLS S
Sbjct: 2722 EYNLSPS 2728
>XP_005252742
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  TEYNLSS 8
          TEY LSS
Sbjct: 52 TEYQLSS 58
>NP_078850
          Length = 568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTEYNLSSS 9
           D EY +SSS
Sbjct: 132 DVEYFISSS 140
>NP_001156909
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 395 DTEYQLN 401
>NP_149106
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 371 DTEYQLN 377
>NP_001156908
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 434 DTEYQLN 440
>NP_001277697
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 262 DTEYQLN 268
>NP_001156907
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 434 DTEYQLN 440
>NP_001073982
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   DTEYNL 6
           DT YNL
Sbjct: 382 DTNYNL 387
>NP_001073379
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DTEYNLSSS 9
            DT +NL S+
Sbjct: 1482 DTSFNLPSN 1490
>NP_001138409
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DTEYNLS 7
           DT+YN++
Sbjct: 429 DTKYNIT 435
>NP_005699
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DTEYNL 6
           DTE+NL
Sbjct: 285 DTEWNL 290
>NP_001107604
          Length = 2694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DTEYNLSSS 9
            +TEYN   S
Sbjct: 2685 ETEYNTQDS 2693
>NP_001269065
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TEYNLSS 8
           ++YNLSS
Sbjct: 221 SDYNLSS 227
>NP_000631
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   DTEYNL 6
           DT YNL
Sbjct: 166 DTNYNL 171
>XP_006719974
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DTEYNL 6
           DTE+NL
Sbjct: 215 DTEWNL 220
>XP_005254074
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   DTEYNL 6
           DTE+NL
Sbjct: 215 DTEWNL 220
>XP_006719697
          Length = 1658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DTEYNLSSS 9
            DT +NL S+
Sbjct: 1418 DTSFNLPSN 1426
>XP_006719696
          Length = 1696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DTEYNLSSS 9
            DT +NL S+
Sbjct: 1418 DTSFNLPSN 1426
>XP_006719695
          Length = 1696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DTEYNLSSS 9
            DT +NL S+
Sbjct: 1418 DTSFNLPSN 1426
>XP_005269238
          Length = 1696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DTEYNLSSS 9
            DT +NL S+
Sbjct: 1418 DTSFNLPSN 1426
>XP_005248831
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TEYNLSS 8
           ++YNLSS
Sbjct: 123 SDYNLSS 129
>XP_005248830
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TEYNLSS 8
           ++YNLSS
Sbjct: 221 SDYNLSS 227
>XP_006715361
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TEYNLSS 8
           ++YNLSS
Sbjct: 221 SDYNLSS 227
>XP_005249448
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DTEYNLSS 8
           + EYNLS+
Sbjct: 252 EEEYNLSA 259
>XP_006714482
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTEYNLS 7
           DTEY L+
Sbjct: 434 DTEYQLN 440
>XP_005269338
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   DTEYNL 6
           DT YNL
Sbjct: 382 DTNYNL 387
>XP_005269337
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   DTEYNL 6
           DT YNL
Sbjct: 382 DTNYNL 387
>XP_006712762
          Length = 2723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    DTEYNLSSS 9
            +TEYN   S
Sbjct: 2714 ETEYNTQDS 2722
>XP_005270607
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   DTEYNLS 7
           DT+YN++
Sbjct: 196 DTKYNIT 202
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.284    0.104    0.250 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 573,430
Number of extensions: 1061
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package