Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     665
XP_006716142                                                           19     665
XP_005250088                                                           19     665
XP_006716141                                                           19     665
XP_005250085                                                           19     665
XP_006716140                                                           19     665
XP_005250084                                                           19     665
XP_005250083                                                           19     665
XP_005250082                                                           19     665
NP_001092880                                                           16    5631
NP_001092881                                                           16    5631
NP_055525                                                              16    5631
NP_000258                                                              16    5631
NP_001035957                                                           16    5631
NP_001171656                                                           16    5631
NP_001005207                                                           16    5631
NP_001171511                                                           16    5631
NP_004168                                                              16    5631
NP_056109                                                              16    5631
XP_006721991                                                           16    5631
XP_006721990                                                           16    5631
XP_006721989                                                           16    5631
XP_005258041                                                           16    5631
XP_006721988                                                           16    5631
XP_006721987                                                           16    5631
XP_006721986                                                           16    5631
XP_005258040                                                           16    5631
XP_006721985                                                           16    5631
XP_005257447                                                           16    5631
XP_005257446                                                           16    5631
XP_005257445                                                           16    5631
XP_005257444                                                           16    5631
XP_005257443                                                           16    5631
XP_005257442                                                           16    5631
XP_005274257                                                           16    5631
XP_005274256                                                           16    5631
XP_005274255                                                           16    5631
XP_005274253                                                           16    5631
XP_005274252                                                           16    5631
XP_006718735                                                           16    5631
NP_644810                                                              15    9605
NP_001005163                                                           15    9605
>NP_733751
          Length = 4911

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 597 DTDSLLIAV 605
>XP_006716142
          Length = 4927

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_005250088
          Length = 4928

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_006716141
          Length = 4959

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_005250085
          Length = 4979

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_006716140
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_005250084
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>XP_005250083
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 597 DTDSLLIAV 605
>XP_005250082
          Length = 4983

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DTDS+LIAV
Sbjct: 598 DTDSLLIAV 606
>NP_001092880
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TDSVLIA 8
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_001092881
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TDSVLIA 8
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_055525
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TDSVLIA 8
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_000258
          Length = 2818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 699 DTEAVLVAM 707
>NP_001035957
          Length = 2839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 699 DTEAVLVAM 707
>NP_001171656
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TDSVLIA 8
           TDSVL+A
Sbjct: 124 TDSVLVA 130
>NP_001005207
          Length = 964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 834 DSDAVVVAV 842
>NP_001171511
          Length = 277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>NP_004168
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>NP_056109
          Length = 964

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 834 DSDAVVVAV 842
>XP_006721991
          Length = 1632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_006721990
          Length = 2823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_006721989
          Length = 2823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_005258041
          Length = 2836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 699 DTEAVLVAM 707
>XP_006721988
          Length = 2846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_006721987
          Length = 2849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_006721986
          Length = 2854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 696 DTEAVLVAM 704
>XP_005258040
          Length = 2857

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 699 DTEAVLVAM 707
>XP_006721985
          Length = 2867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           DT++VL+A+
Sbjct: 709 DTEAVLVAM 717
>XP_005257447
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 834 DSDAVVVAV 842
>XP_005257446
          Length = 925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 834 DSDAVVVAV 842
>XP_005257445
          Length = 930

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 791 DSDAVVVAV 799
>XP_005257444
          Length = 930

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 800 DSDAVVVAV 808
>XP_005257443
          Length = 939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 800 DSDAVVVAV 808
>XP_005257442
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DTDSVLIAV 9
           D+D+V++AV
Sbjct: 834 DSDAVVVAV 842
>XP_005274257
          Length = 252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>XP_005274256
          Length = 265

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>XP_005274255
          Length = 287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>XP_005274253
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>XP_005274252
          Length = 289

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>XP_006718735
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  DTDSVLIAV 9
          DTD+V IA+
Sbjct: 18 DTDAVEIAI 26
>NP_644810
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   DTDSVLI 7
           DTD +LI
Sbjct: 179 DTDGILI 185
>NP_001005163
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DSVLIAV 9
           DS+LIA+
Sbjct: 213 DSILIAI 219
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.133    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,643
Number of extensions: 642
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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