Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1135
XP_006715292                                                           18    1135
NP_001245215                                                           17    2528
NP_001269358                                                           17    2528
NP_001245216                                                           17    2528
NP_775785                                                              17    2528
XP_006714605                                                           17    2528
XP_006714604                                                           17    2528
XP_006714603                                                           17    2528
XP_006714602                                                           17    2528
XP_006714601                                                           17    2528
XP_006714600                                                           17    2528
NP_055873                                                              16    5631
NP_006381                                                              16    5631
NP_003588                                                              16    5631
NP_001171187                                                           16    5631
NP_001171189                                                           16    5631
NP_786951                                                              16    5631
XP_006719854                                                           16    5631
XP_006719853                                                           16    5631
XP_005246236                                                           16    5631
NP_001177924                                                           16    5631
NP_000154                                                              16    7355
NP_001229329                                                           16    7355
NP_001229335                                                           16    7355
NP_001229332                                                           16    7355
NP_001229333                                                           16    7355
NP_001229330                                                           16    7355
NP_001229331                                                           16    7355
NP_001229389                                                           16    7355
NP_001229334                                                           16    7355
NP_001229328                                                           16    7355
NP_006382                                                              16    7355
NP_001136105                                                           16    7355
NP_055123                                                              16    7355
XP_005256637                                                           16    7355
XP_005256636                                                           16    7355
XP_005248345                                                           16    7355
NP_002592                                                              15    9605
NP_689771                                                              15    9605
NP_001274431                                                           15    9605
NP_001274430                                                           15    9605
NP_001274429                                                           15    9605
NP_001274428                                                           15    9605
NP_599025                                                              15    9605
NP_006853                                                              15    9605
NP_001077434                                                           15    9605
NP_001077433                                                           15    9605
NP_001077432                                                           15    9605
NP_001268662                                                           15    9605
NP_075062                                                              15    9605
NP_065811                                                              15    9605
NP_001264                                                              15    9605
NP_001268661                                                           15    9605
XP_006719025                                                           15    9605
XP_005253725                                                           15    9605
XP_006719024                                                           15    9605
XP_006719023                                                           15    9605
XP_006719022                                                           15    9605
XP_006719021                                                           15    9605
XP_006715740                                                           15    9605
XP_006715739                                                           15    9605
XP_006712712                                                           15    9605
XP_006712711                                                           15    9605
XP_006712710                                                           15    9605
XP_006712709                                                           15    9605
XP_005244913                                                           15    9605
XP_005244911                                                           15    9605
XP_005244910                                                           15    9605
NP_602298                                                              15    9605
>NP_115927
          Length = 1321

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TDALLSTS
Sbjct: 315 TDALLSTS 322
>XP_006715292
          Length = 759

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TDALLSTS
Sbjct: 302 TDALLSTS 309
>NP_001245215
          Length = 498

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 177 DTDTILSTN 185
>NP_001269358
          Length = 437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 116 DTDTILSTN 124
>NP_001245216
          Length = 498

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 213 DTDTILSTN 221
>NP_775785
          Length = 561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714605
          Length = 496

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714604
          Length = 531

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714603
          Length = 561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714602
          Length = 561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714601
          Length = 561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>XP_006714600
          Length = 561

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           DTD +LST+
Sbjct: 240 DTDTILSTN 248
>NP_055873
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DTDALLS 7
            DTDALL+
Sbjct: 1486 DTDALLA 1492
>NP_006381
          Length = 1037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DTD LLS +
Sbjct: 704 DTDTLLSNA 712
>NP_003588
          Length = 512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TD+LLST+
Sbjct: 220 TDSLLSTN 227
>NP_001171187
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TD+LLST+
Sbjct: 203 TDSLLSTN 210
>NP_001171189
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TD+LLST+
Sbjct: 203 TDSLLSTN 210
>NP_786951
          Length = 214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           + DALLST+
Sbjct: 197 EADALLSTT 205
>XP_006719854
          Length = 1550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DTDALLS 7
            DTDALL+
Sbjct: 1131 DTDALLA 1137
>XP_006719853
          Length = 1809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DTDALLS 7
            DTDALL+
Sbjct: 1390 DTDALLA 1396
>XP_005246236
          Length = 495

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TDALLSTS 9
           TD+LLST+
Sbjct: 203 TDSLLSTN 210
>NP_001177924
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DTD LLS +
Sbjct: 499 DTDTLLSNA 507
>NP_000154
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229329
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229335
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229332
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229333
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229330
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229331
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229389
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 339 DTDRLLSS 346
>NP_001229334
          Length = 638

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 361 DTDRLLSS 368
>NP_001229328
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 368 DTDRLLSS 375
>NP_006382
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DTDALLS 7
           DTD LLS
Sbjct: 704 DTDTLLS 710
>NP_001136105
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           + D+LLSTS
Sbjct: 342 ERDSLLSTS 350
>NP_055123
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           + D+LLSTS
Sbjct: 342 ERDSLLSTS 350
>XP_005256637
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           + D+LLSTS
Sbjct: 342 ERDSLLSTS 350
>XP_005256636
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DTDALLSTS 9
           + D+LLSTS
Sbjct: 342 ERDSLLSTS 350
>XP_005248345
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           DTD LLS+
Sbjct: 339 DTDRLLSS 346
>NP_002592
          Length = 150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D L+STS
Sbjct: 135 DDDLLVSTS 143
>NP_689771
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 314 DLDRVLSTS 322
>NP_001274431
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 249 DLDRVLSTS 257
>NP_001274430
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 249 DLDRVLSTS 257
>NP_001274429
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 298 DLDRVLSTS 306
>NP_001274428
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 314 DLDRVLSTS 322
>NP_599025
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          DT ALLS +
Sbjct: 11 DTQALLSAT 19
>NP_006853
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_001077434
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_001077433
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 470 ETDASLST 477
>NP_001077432
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_001268662
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          DT ALLS +
Sbjct: 11 DTQALLSAT 19
>NP_075062
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          DT ALLS +
Sbjct: 11 DTQALLSAT 19
>NP_065811
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DT+ L STS
Sbjct: 395 DTEELTSTS 403
>NP_001264
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>NP_001268661
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          DT ALLS +
Sbjct: 11 DTQALLSAT 19
>XP_006719025
          Length = 1902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_005253725
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_006719024
          Length = 1908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_006719023
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_006719022
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_006719021
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          D DALL+ S
Sbjct: 19 DMDALLNNS 27
>XP_006715740
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 169 DLDRVLSTS 177
>XP_006715739
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           D D +LSTS
Sbjct: 249 DLDRVLSTS 257
>XP_006712712
          Length = 1414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DT+ L STS
Sbjct: 237 DTEELTSTS 245
>XP_006712711
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DT+ L STS
Sbjct: 271 DTEELTSTS 279
>XP_006712710
          Length = 1528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DT+ L STS
Sbjct: 402 DTEELTSTS 410
>XP_006712709
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DTDALLSTS 9
           DT+ L STS
Sbjct: 402 DTEELTSTS 410
>XP_005244913
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 291 ETDASLST 298
>XP_005244911
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 515 ETDASLST 522
>XP_005244910
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DTDALLST 8
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_602298
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  DTDALLSTS 9
          DT ALLS +
Sbjct: 11 DTQALLSAT 19
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.112    0.266 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,584
Number of extensions: 676
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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