Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_892006                                                              16    5631
NP_149062                                                              16    5631
XP_006715488                                                           16    5631
XP_006715487                                                           16    5631
XP_006715486                                                           16    5631
XP_006715485                                                           16    5631
XP_006715484                                                           16    5631
XP_006715483                                                           16    5631
XP_006715482                                                           16    5631
XP_006715481                                                           16    5631
XP_006715480                                                           16    5631
XP_006715479                                                           16    5631
XP_006715478                                                           16    5631
XP_006715477                                                           16    5631
XP_006715476                                                           16    5631
XP_006715475                                                           16    5631
XP_006715474                                                           16    5631
XP_006715473                                                           16    5631
XP_006715472                                                           16    5631
XP_006715471                                                           16    5631
XP_006715470                                                           16    5631
NP_055797                                                              16    7355
XP_005267484                                                           16    7355
XP_005267483                                                           16    7355
XP_005267482                                                           16    7355
XP_005267481                                                           16    7355
XP_005267480                                                           16    7355
XP_005267479                                                           16    7355
XP_005267478                                                           16    7355
XP_005267477                                                           16    7355
NP_057240                                                              15    9605
>NP_892006
          Length = 8797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5970 DSLQSISTK 5978
>NP_149062
          Length = 8749

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5899 DSLQSISTK 5907
>XP_006715488
          Length = 8721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715487
          Length = 8744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715486
          Length = 8758

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715485
          Length = 8793

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5924 DSLQSISTK 5932
>XP_006715484
          Length = 8794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5925 DSLQSISTK 5933
>XP_006715483
          Length = 8795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5930 DSLQSISTK 5938
>XP_006715482
          Length = 8797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5970 DSLQSISTK 5978
>XP_006715481
          Length = 8799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5930 DSLQSISTK 5938
>XP_006715480
          Length = 8799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5930 DSLQSISTK 5938
>XP_006715479
          Length = 8804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715478
          Length = 8809

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715477
          Length = 8822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5953 DSLQSISTK 5961
>XP_006715476
          Length = 8823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715475
          Length = 8827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715474
          Length = 8829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5960 DSLQSISTK 5968
>XP_006715473
          Length = 8832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715472
          Length = 8839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5970 DSLQSISTK 5978
>XP_006715471
          Length = 8842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>XP_006715470
          Length = 8846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSVQSASTR 9
            DS+QS ST+
Sbjct: 5977 DSLQSISTK 5985
>NP_055797
          Length = 2341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267484
          Length = 1515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267483
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267482
          Length = 2243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267481
          Length = 2293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 313 DSLRSLSTR 321
>XP_005267480
          Length = 2336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267479
          Length = 2344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267478
          Length = 2348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>XP_005267477
          Length = 2349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSVQSASTR 9
           DS++S STR
Sbjct: 369 DSLRSLSTR 377
>NP_057240
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  DSVQSAST 8
          DS+ SAST
Sbjct: 23 DSLSSAST 30
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289   0.0963    0.213 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 188,687
Number of extensions: 148
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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