Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              20     509
NP_689856                                                              17    3301
NP_006314                                                              17    4312
NP_001036199                                                           17    4312
XP_005262748                                                           17    4312
XP_005262746                                                           17    4312
XP_005262745                                                           17    4312
NP_031392                                                              16    5631
NP_001007268                                                           16    5631
NP_001182570                                                           16    5631
NP_055080                                                              16    5631
NP_002215                                                              16    5631
NP_004237                                                              16    5631
XP_005256918                                                           16    5631
XP_006716338                                                           16    5631
XP_005273438                                                           16    5631
XP_005273435                                                           16    5631
XP_006716336                                                           16    5631
XP_006715155                                                           16    5631
XP_006715154                                                           16    5631
XP_005246450                                                           16    5631
XP_005246449                                                           16    5631
NP_783864                                                              16    7355
NP_009115                                                              16    7355
NP_001017423                                                           16    7355
NP_002851                                                              16    7355
NP_115492                                                              16    7355
NP_005236                                                              16    7355
NP_001014402                                                           16    7355
NP_001127923                                                           16    7355
NP_001127922                                                           16    7355
NP_690877                                                              16    7355
XP_005266631                                                           16    7355
XP_006717996                                                           16    7355
XP_006714202                                                           16    7355
XP_005262892                                                           16    7355
XP_005262891                                                           16    7355
XP_005262701                                                           16    7355
XP_006713018                                                           16    7355
XP_005264896                                                           16    7355
XP_006711845                                                           16    7355
XP_006711211                                                           16    7355
NP_443197                                                              16    7355
NP_001364                                                              15    9605
NP_009121                                                              15    9605
NP_694996                                                              15    9605
NP_001277251                                                           15    9605
NP_005500                                                              15    9605
NP_001277250                                                           15    9605
NP_056127                                                              15    9605
NP_001265227                                                           15    9605
XP_005269527                                                           15    9605
XP_005269526                                                           15    9605
XP_006714623                                                           15    9605
XP_005271970                                                           15    9605
XP_005271969                                                           15    9605
XP_005271967                                                           15    9605
XP_005271966                                                           15    9605
XP_006714407                                                           15    9605
XP_006714406                                                           15    9605
XP_006714405                                                           15    9605
XP_005263349                                                           15    9605
XP_005263348                                                           15    9605
XP_005263347                                                           15    9605
XP_005263346                                                           15    9605
XP_005263345                                                           15    9605
XP_005263344                                                           15    9605
XP_005263343                                                           15    9605
XP_005263342                                                           15    9605
XP_005263341                                                           15    9605
XP_005263340                                                           15    9605
XP_005263339                                                           15    9605
XP_006713727                                                           15    9605
XP_006711798                                                           15    9605
NP_795713                                                              15    9605
>NP_000312
          Length = 928

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DS IVFYNS
Sbjct: 750 DSIIVFYNS 758
>NP_689856
          Length = 1749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SSIVFYN 8
            SS++FYN
Sbjct: 1230 SSLIFYN 1236
>NP_006314
          Length = 1268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS+I FYN
Sbjct: 724 DSTIHFYN 731
>NP_001036199
          Length = 1233

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS+I FYN
Sbjct: 689 DSTIHFYN 696
>XP_005262748
          Length = 1263

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS+I FYN
Sbjct: 719 DSTIHFYN 726
>XP_005262746
          Length = 1298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS+I FYN
Sbjct: 754 DSTIHFYN 761
>XP_005262745
          Length = 1299

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS+I FYN
Sbjct: 755 DSTIHFYN 762
>NP_031392
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DSS++F N
Sbjct: 455 DSSVIFTN 462
>NP_001007268
          Length = 1324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DSS++F N
Sbjct: 455 DSSVIFTN 462
>NP_001182570
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DSS++F N
Sbjct: 455 DSSVIFTN 462
>NP_055080
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DSS+VF+ S
Sbjct: 658 DSSVVFHFS 666
>NP_002215
          Length = 2671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DSSIVFYN 8
            D  +VFYN
Sbjct: 1330 DDVVVFYN 1337
>NP_004237
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IVFYNS 9
           +VFYNS
Sbjct: 233 VVFYNS 238
>XP_005256918
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  IVFYNS 9
          +VFYNS
Sbjct: 80 VVFYNS 85
>XP_006716338
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DSS+VF+ S
Sbjct: 568 DSSVVFHFS 576
>XP_005273438
          Length = 732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DSS+VF+ S
Sbjct: 658 DSSVVFHFS 666
>XP_005273435
          Length = 754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DSS+VF+ S
Sbjct: 658 DSSVVFHFS 666
>XP_006716336
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DSS+VF+ S
Sbjct: 658 DSSVVFHFS 666
>XP_006715155
          Length = 1850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DSSIVFYN 8
            D  +VFYN
Sbjct: 1359 DDVVVFYN 1366
>XP_006715154
          Length = 2700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    DSSIVFYN 8
            D  +VFYN
Sbjct: 1359 DDVVVFYN 1366
>XP_005246450
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DSS++F N
Sbjct: 455 DSSVIFTN 462
>XP_005246449
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DSS++F N
Sbjct: 455 DSSVIFTN 462
>NP_783864
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSIVFYN 8
           SSI FYN
Sbjct: 953 SSIQFYN 959
>NP_009115
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SSIVFYNS 9
            SS+VFY +
Sbjct: 1164 SSVVFYQT 1171
>NP_001017423
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DS+ VF+N+
Sbjct: 713 DSACVFWNA 721
>NP_002851
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DS+ VF+N+
Sbjct: 715 DSACVFWNA 723
>NP_115492
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DSSIVFY 7
          DSS+V+Y
Sbjct: 23 DSSMVYY 29
>NP_005236
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>NP_001014402
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DSSIVFY 7
          DSS+V+Y
Sbjct: 23 DSSMVYY 29
>NP_001127923
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  DSSIVFYN 8
          + S+V+YN
Sbjct: 88 EDSVVYYN 95
>NP_001127922
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           + S+V+YN
Sbjct: 190 EDSVVYYN 197
>NP_690877
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           + S+V+YN
Sbjct: 190 EDSVVYYN 197
>XP_005266631
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  DSSIVFY 7
          DSS+V+Y
Sbjct: 23 DSSMVYY 29
>XP_006717996
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           DS+ VF+N+
Sbjct: 715 DSACVFWNA 723
>XP_006714202
          Length = 4588

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_005262892
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_005262891
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++F NS
Sbjct: 734 SSVIFMNS 741
>XP_005262701
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SSIVFYN 8
           SSI FYN
Sbjct: 944 SSIQFYN 950
>XP_006713018
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS+VFY +
Sbjct: 658 SSVVFYQT 665
>XP_005264896
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS+VFY +
Sbjct: 773 SSVVFYQT 780
>XP_006711845
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSSIVFYNS 9
           +SSIVF N+
Sbjct: 429 NSSIVFVNT 437
>XP_006711211
          Length = 183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DSSIVFY 7
           DS+IV+Y
Sbjct: 147 DSTIVYY 153
>NP_443197
          Length = 171

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DSSIVFY 7
           DS+IV+Y
Sbjct: 147 DSTIVYY 153
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            S I+FYN
Sbjct: 1402 SQIMFYN 1408
>NP_009121
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IVFYNS 9
           I+FYNS
Sbjct: 539 ILFYNS 544
>NP_694996
          Length = 2526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DSSIVFY 7
           DSS+VF+
Sbjct: 777 DSSLVFH 783
>NP_001277251
          Length = 2854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSSIVFYN 8
           DS++V YN
Sbjct: 940 DSNLVAYN 947
>NP_005500
          Length = 3027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>NP_001277250
          Length = 3048

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>NP_056127
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>NP_001265227
          Length = 2614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   DSSIVFY 7
           DSS+VF+
Sbjct: 777 DSSLVFH 783
>XP_005269527
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IVFYNS 9
           I+FYNS
Sbjct: 492 ILFYNS 497
>XP_005269526
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IVFYNS 9
           I+FYNS
Sbjct: 539 ILFYNS 544
>XP_006714623
          Length = 1625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>XP_005271970
          Length = 2931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>XP_005271969
          Length = 3020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1047 DSNLVAYN 1054
>XP_005271967
          Length = 3065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>XP_005271966
          Length = 3086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSSIVFYN 8
            DS++V YN
Sbjct: 1113 DSNLVAYN 1120
>XP_006714407
          Length = 5004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2345 SSVSFYN 2351
>XP_006714406
          Length = 3680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_006714405
          Length = 4103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 1423 SSVSFYN 1429
>XP_005263349
          Length = 4410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 1730 SSVSFYN 1736
>XP_005263348
          Length = 4443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 1763 SSVSFYN 1769
>XP_005263347
          Length = 4640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263346
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2303 SSVSFYN 2309
>XP_005263345
          Length = 4991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263344
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263343
          Length = 5009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263342
          Length = 5025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2345 SSVSFYN 2351
>XP_005263341
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263340
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_005263339
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            SS+ FYN
Sbjct: 2346 SSVSFYN 2352
>XP_006713727
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++FY +
Sbjct: 119 SSVIFYET 126
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    SSIVFYN 8
            S I+FYN
Sbjct: 1419 SQIMFYN 1425
>NP_795713
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   SSIVFYNS 9
           SS++FY +
Sbjct: 119 SSVIFYET 126
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.128    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 472,512
Number of extensions: 933
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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