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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              20     299
NP_976241                                                              17    2528
NP_998754                                                              17    2528
XP_005246837                                                           17    2528
XP_005246836                                                           17    2528
XP_006712758                                                           17    2528
XP_005246834                                                           17    2528
NP_001240756                                                           17    4312
NP_055612                                                              17    4312
NP_001157785                                                           17    4312
XP_005265948                                                           17    4312
NP_001265209                                                           16    5631
NP_060916                                                              16    5631
NP_001265210                                                           16    5631
NP_690909                                                              16    5631
NP_001010983                                                           16    5631
NP_919226                                                              16    5631
XP_006713323                                                           16    5631
NP_000060                                                              16    7355
NP_291025                                                              16    7355
XP_005245535                                                           16    7355
NP_064630                                                              15    9605
NP_001137434                                                           15    9605
NP_001269280                                                           15    9605
NP_065901                                                              15    9605
NP_001093254                                                           15    9605
NP_004727                                                              15    9605
NP_001129141                                                           15    9605
XP_006722081                                                           15    9605
XP_005256127                                                           15    9605
XP_005267114                                                           15    9605
NP_060644                                                              15    9605

>NP_443179
          Length = 2170

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DS VANKQP
Sbjct: 287 DSAVANKQP 295



>NP_976241
          Length = 644

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 607 DSGVSDTQP 615



>NP_998754
          Length = 1250

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 555 DSGVSDTQP 563



>XP_005246837
          Length = 1277

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 582 DSGVSDTQP 590



>XP_005246836
          Length = 1302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 607 DSGVSDTQP 615



>XP_006712758
          Length = 1302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 607 DSGVSDTQP 615



>XP_005246834
          Length = 1302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSGVANKQP 9
           DSGV++ QP
Sbjct: 607 DSGVSDTQP 615



>NP_001240756
          Length = 532

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  DSGVANKQP 9
          DSG+++ QP
Sbjct: 16 DSGLSSSQP 24



>NP_055612
          Length = 697

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSGVANKQ 8
           DSGV N+Q
Sbjct: 203 DSGVLNEQ 210



>NP_001157785
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSGVANKQ 8
           DSGV N+Q
Sbjct: 203 DSGVLNEQ 210



>XP_005265948
          Length = 273

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   VANKQP 9
           VANKQP
Sbjct: 183 VANKQP 188



>NP_001265209
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_060916
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_001265210
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_690909
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_001010983
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_919226
          Length = 1209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    DSGVANKQP 9
            +SG+ N QP
Sbjct: 995  NSGILNTQP 1003



>XP_006713323
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSG+   QP
Sbjct: 39 DSGIVGPQP 47



>NP_000060
          Length = 1873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          D G+  KQP
Sbjct: 8  DEGLRKKQP 16



>NP_291025
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SGVANKQ 8
           SGV NKQ
Sbjct: 712 SGVENKQ 718



>XP_005245535
          Length = 1854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          D G+  KQP
Sbjct: 8  DEGLRKKQP 16



>NP_064630
          Length = 1543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VANKQP 9
            +ANKQP
Sbjct: 1467 MANKQP 1472



>NP_001137434
          Length = 703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          DSGV  K P
Sbjct: 41 DSGVLFKDP 49



>NP_001269280
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SGVANKQP 9
           SGV  +QP
Sbjct: 166 SGVVRRQP 173



>NP_065901
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1  DSGVANKQP 9
          D G  N QP
Sbjct: 7  DPGAGNPQP 15



>NP_001093254
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   SGVANKQP 9
           SGV  +QP
Sbjct: 478 SGVVRRQP 485



>NP_004727
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DSGVANKQ 8
           D GV N+Q
Sbjct: 649 DDGVRNRQ 656



>NP_001129141
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   DSGVANKQ 8
           D GV N+Q
Sbjct: 584 DDGVRNRQ 591



>XP_006722081
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  DSGVANKQP 9
          D+G A  QP
Sbjct: 7  DNGTAQPQP 15



>XP_005256127
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1  DSGVANKQP 9
          D G  N QP
Sbjct: 7  DPGAGNPQP 15



>XP_005267114
          Length = 1543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    VANKQP 9
            +ANKQP
Sbjct: 1467 MANKQP 1472



>NP_060644
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   GVANKQP 9
           GVA K+P
Sbjct: 500 GVARKEP 506



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.119    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 608,876
Number of extensions: 1326
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)