Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_078966                                                              17    3301
NP_055325                                                              17    3301
NP_149015                                                              17    3301
XP_006715989                                                           17    3301
NP_570853                                                              17    4312
NP_570854                                                              17    4312
NP_000453                                                              17    4312
XP_005268328                                                           17    4312
XP_006720739                                                           17    4312
XP_005268327                                                           17    4312
XP_005268326                                                           17    4312
XP_005268324                                                           17    4312
XP_005268325                                                           17    4312
XP_006720738                                                           17    4312
XP_006720737                                                           17    4312
XP_006720736                                                           17    4312
NP_064448                                                              17    4312
NP_061928                                                              16    5631
XP_005271654                                                           16    5631
XP_005271653                                                           16    5631
XP_006718924                                                           16    5631
NP_055446                                                              16    7355
NP_115665                                                              16    7355
XP_005270355                                                           16    7355
XP_006718143                                                           16    7355
XP_005270354                                                           16    7355
XP_005270352                                                           16    7355
XP_005270351                                                           16    7355
XP_006718142                                                           16    7355
XP_006714864                                                           16    7355
NP_001243092                                                           15    9605
NP_001243095                                                           15    9605
NP_001157                                                              15    9605
NP_055928                                                              15    9605
NP_001274685                                                           15    9605
NP_001274679                                                           15    9605
NP_001274678                                                           15    9605
NP_001274680                                                           15    9605
NP_001274672                                                           15    9605
NP_001274673                                                           15    9605
NP_001274674                                                           15    9605
NP_004453                                                              15    9605
NP_001274677                                                           15    9605
NP_001274671                                                           15    9605
NP_001274676                                                           15    9605
NP_067652                                                              15    9605
NP_620636                                                              15    9605
NP_001157915                                                           15    9605
NP_071442                                                              15    9605
NP_003062                                                              15    9605
NP_056381                                                              15    9605
XP_006726897                                                           15    9605
XP_006724471                                                           15    9605
XP_005256619                                                           15    9605
XP_006721549                                                           15    9605
XP_006721548                                                           15    9605
XP_005256618                                                           15    9605
XP_005256617                                                           15    9605
XP_006716310                                                           15    9605
XP_005248537                                                           15    9605
XP_005248536                                                           15    9605
XP_005247781                                                           15    9605
XP_005271152                                                           15    9605
XP_005271151                                                           15    9605
XP_006710181                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3439 SEISSSRT 3446
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3455 SEISSSRT 3462
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            SEISSSRT
Sbjct: 3456 SEISSSRT 3463
>NP_078966
          Length = 14507

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    SEISSSRT 9
            +EISSSRT
Sbjct: 5522 TEISSSRT 5529
>NP_055325
          Length = 4935

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    DSEISSSR 8
            DSE+SS+R
Sbjct: 3836 DSEVSSTR 3843
>NP_149015
          Length = 5142

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    DSEISSSR 8
            DSE+SS+R
Sbjct: 3836 DSEVSSTR 3843
>XP_006715989
          Length = 5148

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    DSEISSSR 8
            DSE+SS+R
Sbjct: 3836 DSEVSSTR 3843
>NP_570853
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>NP_570854
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 203 DSEASSSR 210
>NP_000453
          Length = 875

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 206 DSEASSSR 213
>XP_005268328
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_006720739
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_005268327
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_005268326
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_005268324
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_005268325
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_006720738
          Length = 852

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 183 DSEASSSR 190
>XP_006720737
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 203 DSEASSSR 210
>XP_006720736
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSSR
Sbjct: 203 DSEASSSR 210
>NP_064448
          Length = 327

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           D EISSSR
Sbjct: 161 DREISSSR 168
>NP_061928
          Length = 1007

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ISS R+
Sbjct: 982 DSQISSQRS 990
>XP_005271654
          Length = 862

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ISS R+
Sbjct: 837 DSQISSQRS 845
>XP_005271653
          Length = 862

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ISS R+
Sbjct: 837 DSQISSQRS 845
>XP_006718924
          Length = 969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ISS R+
Sbjct: 944 DSQISSQRS 952
>NP_055446
          Length = 1105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 229 DSDINTSKT 237
>NP_115665
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DSEISSS 7
           DSE+SSS
Sbjct: 286 DSELSSS 292
>XP_005270355
          Length = 968

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  DSEISSSRT 9
          DS+I++S+T
Sbjct: 64 DSDINTSKT 72
>XP_006718143
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 95  DSDINTSKT 103
>XP_005270354
          Length = 1014

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 110 DSDINTSKT 118
>XP_005270352
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 214 DSDINTSKT 222
>XP_005270351
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 229 DSDINTSKT 237
>XP_006718142
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   DSEISSSRT 9
           DS+I++S+T
Sbjct: 260 DSDINTSKT 268
>XP_006714864
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   DSEISSS 7
           DSE+SSS
Sbjct: 286 DSELSSS 292
>NP_001243092
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EISSSRT 9
           +ISSSRT
Sbjct: 168 DISSSRT 174
>NP_001243095
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EISSSRT 9
           +ISSSRT
Sbjct: 119 DISSSRT 125
>NP_001157
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EISSSRT 9
           +ISSSRT
Sbjct: 168 DISSSRT 174
>NP_055928
          Length = 2961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSEISSSR 8
            DSE+SS +
Sbjct: 2059 DSEVSSQK 2066
>NP_001274685
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 184 DSDPSSSKT 192
>NP_001274679
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 410 DSDPSSSKT 418
>NP_001274678
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 287 DSDPSSSKT 295
>NP_001274680
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 266 DSDPSSSKT 274
>NP_001274672
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 351 DSDPSSSKT 359
>NP_001274673
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 287 DSDPSSSKT 295
>NP_001274674
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 287 DSDPSSSKT 295
>NP_004453
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 351 DSDPSSSKT 359
>NP_001274677
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 287 DSDPSSSKT 295
>NP_001274671
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 351 DSDPSSSKT 359
>NP_001274676
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 287 DSDPSSSKT 295
>NP_067652
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           D+E SSS T
Sbjct: 459 DTETSSSET 467
>NP_620636
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SEISSSR 8
           SE+SSSR
Sbjct: 378 SELSSSR 384
>NP_001157915
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    DSEISSS 7
            DS+ISSS
Sbjct: 1667 DSQISSS 1673
>NP_071442
          Length = 690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SEISSSRT 9
           SEI S+RT
Sbjct: 453 SEIQSTRT 460
>NP_003062
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SEISSSR 8
           SE+SSSR
Sbjct: 378 SELSSSR 384
>NP_056381
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSS+
Sbjct: 344 DSEFSSSQ 351
>XP_006726897
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           DSE+  S+T
Sbjct: 142 DSEVPQSKT 150
>XP_006724471
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           DSE+  S+T
Sbjct: 142 DSEVPQSKT 150
>XP_005256619
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE+SS +
Sbjct: 675 DSEVSSQK 682
>XP_006721549
          Length = 1581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE+SS +
Sbjct: 675 DSEVSSQK 682
>XP_006721548
          Length = 1886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE+SS +
Sbjct: 980 DSEVSSQK 987
>XP_005256618
          Length = 2962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSEISSSR 8
            DSE+SS +
Sbjct: 2060 DSEVSSQK 2067
>XP_005256617
          Length = 2966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    DSEISSSR 8
            DSE+SS +
Sbjct: 2060 DSEVSSQK 2067
>XP_006716310
          Length = 358

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSEISSSRT 9
           DS+ SSS+T
Sbjct: 292 DSDPSSSKT 300
>XP_005248537
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSS+
Sbjct: 344 DSEFSSSQ 351
>XP_005248536
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSEISSSR 8
           DSE SSS+
Sbjct: 406 DSEFSSSQ 413
>XP_005247781
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SEISSSR 8
           SE+SSSR
Sbjct: 378 SELSSSR 384
>XP_005271152
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           D+E SSS T
Sbjct: 459 DTETSSSET 467
>XP_005271151
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           D+E SSS T
Sbjct: 459 DTETSSSET 467
>XP_006710181
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   DSEISSSRT 9
           DSE+  S+T
Sbjct: 142 DSEVPQSKT 150
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0974    0.209 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 424,782
Number of extensions: 785
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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