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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           20     509
NP_000170                                                              20     509
NP_001268422                                                           20     509
NP_001268423                                                           20     509
XP_005264328                                                           20     509
NP_694984                                                              16    5631
XP_006724701                                                           16    5631
XP_005262172                                                           16    5631
XP_005262170                                                           16    5631
NP_001191330                                                           16    7355
NP_001158                                                              16    7355
NP_003244                                                              16    7355
NP_115984                                                              16    7355
NP_003146                                                              16    7355
XP_006724817                                                           16    7355
XP_005261096                                                           16    7355
XP_005261095                                                           16    7355
XP_005261094                                                           16    7355
NP_005436                                                              15    9605
NP_877439                                                              15    9605
NP_690007                                                              15    9605
NP_060439                                                              15    9605
NP_690008                                                              15    9605
NP_071907                                                              15    9605
XP_006726589                                                           15    9605
XP_005259213                                                           15    9605
XP_005259212                                                           15    9605
XP_005259211                                                           15    9605
XP_006723388                                                           15    9605
XP_005259210                                                           15    9605
XP_006723387                                                           15    9605
XP_005259209                                                           15    9605
XP_006718462                                                           15    9605
XP_006712689                                                           15    9605
XP_005263764                                                           15    9605
XP_006710010                                                           15    9605
NP_690009                                                              15    9605

>NP_001268421
          Length = 1230

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           DSD VSTTR
Sbjct: 583 DSDTVSTTR 591



>NP_000170
          Length = 1360

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           DSD VSTTR
Sbjct: 713 DSDTVSTTR 721



>NP_001268422
          Length = 1058

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           DSD VSTTR
Sbjct: 411 DSDTVSTTR 419



>NP_001268423
          Length = 1058

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           DSD VSTTR
Sbjct: 411 DSDTVSTTR 419



>XP_005264328
          Length = 1261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           DSD VSTTR
Sbjct: 614 DSDTVSTTR 622



>NP_694984
          Length = 1802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSDAVSTTR 9
            DSD+ ST+R
Sbjct: 1622 DSDSESTSR 1630



>XP_006724701
          Length = 1398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSDAVSTTR 9
            DSD+ ST+R
Sbjct: 1218 DSDSESTSR 1226



>XP_005262172
          Length = 1631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSDAVSTTR 9
            DSD+ ST+R
Sbjct: 1451 DSDSESTSR 1459



>XP_005262170
          Length = 1752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    DSDAVSTTR 9
            DSD+ ST+R
Sbjct: 1572 DSDSESTSR 1580



>NP_001191330
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           +SDAVS+ R
Sbjct: 240 ESDAVSSDR 248



>NP_001158
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           +SDAVS+ R
Sbjct: 240 ESDAVSSDR 248



>NP_003244
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DSDAVSTT 8
            DSDAVS +
Sbjct: 1458 DSDAVSAS 1465



>NP_115984
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   DSDAVSTT 8
           D+DAVS T
Sbjct: 200 DADAVSPT 207



>NP_003146
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   DSDAVSTTR 9
           D D VST R
Sbjct: 171 DEDTVSTIR 179



>XP_006724817
          Length = 497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   DSDAVSTTR 9
           +SDAVS+ R
Sbjct: 240 ESDAVSSDR 248



>XP_005261096
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DSDAVSTT 8
            DSDAVS +
Sbjct: 1458 DSDAVSAS 1465



>XP_005261095
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DSDAVSTT 8
            DSDAVS +
Sbjct: 1458 DSDAVSAS 1465



>XP_005261094
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    DSDAVSTT 8
            DSDAVS +
Sbjct: 1458 DSDAVSAS 1465



>NP_005436
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   DSDAVST 7
           DSD VST
Sbjct: 564 DSDEVST 570



>NP_877439
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SDAVSTTR 9
           SD+V TTR
Sbjct: 626 SDSVFTTR 633



>NP_690007
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 280 DSDAVS 285



>NP_060439
          Length = 819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 421 DSDAVS 426



>NP_690008
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 282 DSDAVS 287



>NP_071907
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 213 DSDAVS 218



>XP_006726589
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DSDAVSTT 8
           DSD  STT
Sbjct: 110 DSDCPSTT 117



>XP_005259213
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 326 DSDAVS 331



>XP_005259212
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 326 DSDAVS 331



>XP_005259211
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 213 DSDAVS 218



>XP_006723388
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 213 DSDAVS 218



>XP_005259210
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 231 DSDAVS 236



>XP_006723387
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 280 DSDAVS 285



>XP_005259209
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 326 DSDAVS 331



>XP_006718462
          Length = 4966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    DSDAVSTT 8
            DSD  STT
Sbjct: 4135 DSDCPSTT 4142



>XP_006712689
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 426 DSDAVS 431



>XP_005263764
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 426 DSDAVS 431



>XP_006710010
          Length = 1103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   DSDAVSTT 8
           DSD  STT
Sbjct: 331 DSDCPSTT 338



>NP_690009
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   DSDAVS 6
           DSDAVS
Sbjct: 213 DSDAVS 218



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.106    0.255 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 371,291
Number of extensions: 468
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)